Circadian periodicity of cerebral blood flow revealed by laser-Doppler flowmetry in awake rats: Relation to blood pressure and activity

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 289, Issue 4 58-4, 2005, Pages

  Wauschkuhn, C A ^a,c   Witte, K ^a,d   Gorbey, S ^a   Lemmer, B ^a   Schilling, L ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c MARIENHOSPITAL STUTTGART   (Germany)

^d Solvay Pharmaceuticals GmbH   (Germany)

Author keywords

Arterial blood pressure; Cerebral perfusion; Circadian rhythm; Locomotor activity; Radiotelemetry

Indexed keywords

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; BRAIN BLOOD FLOW; CEREBROVASCULAR DISEASE; CIRCADIAN RHYTHM; FLOW; HEART RATE; HYPERTENSION; LASER DOPPLER FLOW; LASER DOPPLER FLOWMETRY; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TELEMETRY; TRANSGENIC ANIMAL; TRANSGENIC RAT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD PRESSURE; CEREBROVASCULAR CIRCULATION; CIRCADIAN RHYTHM; LASER-DOPPLER FLOWMETRY; MONITORING, PHYSIOLOGIC; MOTOR ACTIVITY; PERIODICITY; RATS; RATS, SPRAGUE-DAWLEY; TELEMETRY; WAKEFULNESS;

EID: 25444529669     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01242.2004     Document Type: Article

References (49)

1. Ashkar E. Twenty-four-hour pattern of circulation by radiotelemetry in the unrestrained dog. Am J Physiol Regul Integr Comp Physiol 236: R231-R236, 1979.
2. Betz E. Local heat clearance from the brain as a measure of blood flow in acute and chronic experiments. Acta Neurol Scand Suppl 14: 29-37, 1965.
3. Birzis L and Tachibana S. Local cerebral impedance and blood flow during sleep and arousal. Exp Neurol 9: 269-285, 1964.
4. Caspary L, Nordbruch S, Lange R, and Creutzig A. Circadian variation of skin perfusion in arterial occlusive disease. Vasa 26: 194-198, 1997.
5. Chaturvedi S, Adams HP, and Woolson RF. Circadian variation in ischemic stroke subtypes. Stroke 30: 1792-1795, 1999.
6. Cugini P, Di Palma L, Di Simone S, Lucia P, Battisti P, Coppola A, and Leone G. Circadian rhythm of cardiac output, peripheral vascular resistance, and related variables by a beat-to-beat monitoring. Chronobiol Int 10: 73-78, 1993.
7. Delp MD, Manning RO, Bruckner JV, and Armstrong RB. Distribution of cardiac output during diurnal changes of activity in rats. Am J Physiol Heart Circ Physiol 261: H1487-H1493, 1991.
8. Diamant M, Harms MP, Immink RV, van Lieshout JJ, and van Montfrans GA. Twenty-four-hour non-invasive monitoring of systemic haemodynamics and cerebral blood flow velocity in healthy humans. Acta Physiol Scand 175: 1-9, 2002.
9. Elherik K, Khan F, McLaren M, Kennedy G, and Belch JJ. Circadian variation in vascular tone and endothelial cell function in normal males. Clin Sci (Lond) 102: 547-552, 2002.
10. Elliott WJ. Cyclic and circadian variations in cardiovascular events. Am J Hypertens 14: 291S-295S, 2001.
11. Endo Y, Jinnai K, Endo M, Fujita K, and Kimura F. Diurnal variation of cerebral blood flow in rat hippocampus. Stroke 21: 1464-1469, 1990.
12. Fogelholm RR, Turjanmaa VM, Nuutila MT, Murros KE, and Sarna S. Diurnal blood pressure variations and onset of subarachnoid haemorrhage: a population-based study. J Hypertens 13: 495-498, 1995.
13. Fujita M and Franklin D. Diurnal changes in coronary blood flow in conscious dogs. Circulation 76: 488-491, 1987.
14. Fukuda O, Endo S, Kuwayama N, Harada J, and Takaku A. The characteristics of laser-Doppler flowmetry for the measurement of regional cerebral blood flow. Neurosurgery 36: 358-364, 1995.
15. Gallerani M, Portaluppi F, Maida G, Chieregato A, Calzolari F, Trapella G, and Manfredini R. Circadian and circannual rhythmicity in the occurrence of subarachnoid hemorrhage. Stroke 27: 1793-1797, 1996.
16. Gerashchenko D and Matsumura H. Continuous recordings of brain regional circulation during sleep/wake state transitions in rats. Am J Physiol Regul Integr Comp Physiol 270: R855-R863, 1996.
17. Gu W, Jiang W, and Wester P. Real-time cortical cerebral blood flow follow-up in conscious, freely moving rats by laser Doppler flowmetry. Methods 30: 172-177, 2003.
18. Gu WG, Jiang W, Brännström T, and Wester P. Long-term cortical CBF recording by laser-Doppler flowmetry in awake freely moving rats subjected to reversible photothrombotic stroke. J Neurosci Methods 90: 23-32, 1999.
19. Gush RJ and King TA. Investigation and improved performance of optical fibre probes in laser Doppler blood flow measurement. Med Biol Eng Comput 25: 391-396, 1987.
20. Haberl RL, Heizer ML, Marmarou A, and Ellis EF. Laser-Doppler assessment of brain microcirculation: effect of systemic alterations. Am J Physiol Heart Circ Physiol 256: H1247-H1254, 1989.
21. Houben AJHM, Slaaf DW, Huvers FC, de Leeuw PW, Nieuwenhuijzen Kruseman AC, and Schaper NC. Diurnal variations in total forearm and skin microcirculatory blood flow in man. Scand J Clin Lab Invest 54: 161-168, 1994.
22. Kirkeby OJ, Rise IR, Nordsletten L, Skjeldal S, Hall C, and Risöe C. Cerebral blood flow measured with intracerebral laser-Doppler flow probes and radioactive microspheres. J Appl Physiol 79: 1479-1486, 1995.
23. Kramer IC and Kinter LB. Evaluation and applications of radiotelemetry in small laboratory animals. Physiol Genomics 13: 197-205, 2003.
24. Lemmer B, Mattes A, Böhm M, and Ganten D. Circadian blood pressure variation in transgenic hypertensive rats. Hypertension 22: 97-101, 1993.
25. Lemmer B and Portaluppi F. Chronopharmacology of cardiovascular diseases. In: Physiology and Pharmacology of Biological Rhythms, edited by Redfern PH and Lemmer B. Berlin: Springer, 1987, p. 251-297.
26. Lemmer B, Witte K, Enzminger H, Schiffer S, and Hauptfleisch S. Transgenic TGR (mREN2)27 rats as a model for disturbed circadian organization at the level of the brain, the heart, and the kidneys. Chronobiol Int 20: 711-738, 2003.
27. Lenzi P, Cianci T, Guidalotti PL, Leonardi GS, and Franzini C. Brain circulation during sleep and its relation to extracerebral hemodynamics. Brain Res 415: 14-20, 1987.
28. Marler JR, Price TR, Clark GL, Muller JE, Robertson T, Mohr JP, Hier DB, Wolf PA, Caplan LR, and Foulkes MA. Morning increase in onset of ischemic stroke. Stroke 20: 473-476, 1989.
29. Muller JE, Stone PH, Turi ZG, Rutherford JD, Czeisler CA, Parker C, Poole WK, Passamani E, Roberts R, and Robertson T. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med 313: 1315-1322, 1985.
30. Newson TP, Obeid A, Wolton RS, Boggett D, and Rolfe P. Laser Doppler velocimetry: the problem of fibre movement artefact. J Biomed Eng 9: 169-172, 1987.
31. Nitzan M, Mahler Y, and Roberts VC. The transient thermal clearance method for regional blood flow measurement-the influence of tissue heat conduction. Clin Phys Physiol Meas 9: 339-346, 1988.
32. Nyquist PA, Brown RD, Wiebers DO, Crowson CS, and O'Fallon WM. Circadian and seasonal occurrence of subarachnoid and intracerebral hemorrhage. Neurology 56: 190-193, 2001.
33. Osborne PG. Hippocampal and striatal blood flow during behavior in rats: chronic laser Doppler flowmetry study. Physiol Behav 61: 485-492, 1997.
34. Otto ME, Svatikova A, Barretto RB, Santos S, Hoffmann M, Khandheria B, and Somers V. Early morning attenuation of endothelial function in healthy humans. Circulation 109: 2507-2510, 2004.
35. Panza JA, Epstein SE, and Quyyumi AA. Circadian variation in vascular tone and its relation to α-sympathetic vasoconstrictor activity. N Engl J Med 325: 986-990, 1991.
36. Pons M, Schnecke A, Witte K, Lemmer B, Waterhouse JM, and Cambar J. Circadian rhythms in renal function in hypertensive TGR(m-Ren-2)27 rats and their normotensive controls. Am J Physiol Regul Integr Comp Physiol 271: R1002-R1008, 1996.
37. Ricci S, Celani MG, Vitali R, La Rosa F, Righetti E, and Duca E. Diurnal and seasonal variations in the occurrence of stroke: a community-based study. Neuroepidemiology 11: 59-64, 1992.
38. Ringqvist A, Caidahl K, Petersson AS, and Wennmalm A. Diurnal variation of flow-mediated vasodilation in healthy premenopausal women. Am J Physiol Heart Circ Physiol 279: H2720-H2755, 2000.
39. Roussel B, Dittmar A, and Chouvet G. Internal temperature variations during the sleep-wake cycle in the rat. Waking Sleeping 4: 63-75, 1980.
40. Skarphedinsson JO, Harding H, and Thoren P. Repeated measurements of cerebral blood flow in rats: comparisons between the hydrogen clearance method and laser Doppler flowmetry. Acta Physiol Scand 134: 133-142, 1988.
41. Smith TL, Coleman TG, Stanek KA, and Murphy WR. Hemodynamic monitoring for 24 h in unanesthetized rats. Am J Physiol Heart Circ Physiol 253: H1335-H1341, 1987.
42. Smolensky MH and Haus E. Circadian rhythms and clinical medicine with applications to hypertension. Am J Hypertens 14: 280S-290S, 2001.
43. Strike PC and Steptoe A. New insights into the mechanisms of temporal variation in the incidence of acute coronary syndromes. Clin Cordial 26: 495-499, 2003.
44. Townsend RE, Prinz PN, and Obrist WD. Human cerebral blood flow during sleep and waking. J Appl Physiol 35: 620-625, 1973.
45. Van Dongen HP, Olofsen E, vanHartevelt JH, and Kruyt EW. Searching for biological rhythms: peak detection in the periodogram of unequally spaced data. J Biol Rhythms 14: 617-620, 1999.
46. Vermeer SE, Rinkel GJ, and Algra A. Circadian fluctuations in onset of subarachnoid hemorrhage. New data on aneurysmal and perimesencephalic hemorrhage and a systematic review. Stroke 28: 805-808, 1997.
47. Witte K, Hasenberg T, Rueff T, Hauptfleisch S, Schilling L, and Lemmer B. Day-night variation in the in vitro contractility of aorta and mesenteric and renal arteries in transgenic hypertensive rats. Chronobiol Int 18: 665-681, 2001.
48. Yosipovitch G, Sackett-Lundeen L, Goon A, Yiong Huak C, Leok Goh C, and Haus E. Circadian and ultradian (12 h) variations of skin blood flow and barrier function in non-irritated and irritated skin-effect of topical corticosteroids. J Invest Dermatol 122: 824-829, 2004.
49. Zuther P, Witte K, and Lemmer B. ABPM-FIT and CV-SORT: an easy-to-use software package for detailed analysis of data from ambulatory blood pressure monitoring. Blood Press Monit 1: 347-354, 1996.