Enhanced absorption of 3-O-methyl glucose following gastrointestinal injury induced by repeated oral administration of 5-FU in mice

Journal of Pharmaceutical Sciences

Volumn 94, Issue 8, 2005, Pages 1713-1722

  Hakata, Tomoko ^a   Ito, Kousei ^a   Horie, Toshiharu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

5 FU; Absorption; Glucose; Mice

Indexed keywords

3 METHYLGLUCOSE; FLUOROURACIL; GLUCOSE; GLUCOSE TRANSPORTER 2; MESSENGER RNA; PHLORETIN; SODIUM GLUCOSE COTRANSPORTER 1;

ANIMAL EXPERIMENT; ARTICLE; BASOLATERAL MEMBRANE; BRUSH BORDER; CONTROLLED STUDY; DIGESTIVE SYSTEM INJURY; DOSE RESPONSE; DRUG INHIBITION; GLUCOSE ABSORPTION; INTESTINE ABSORPTION; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; WEIGHT REDUCTION;

EID: 25444516223     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20388     Document Type: Article

References (38)

1. Stevens BR. 1992. Vertebrate intestine apical membrane mechanisms of organic nutrient transport. Am J Physiol 263:R458-R463.
2. Cheeseman C. 1992. Role of intestinal basolateral membrane in absorption of nutrients. Am J Physiol 263:R482-R488.
3. Mizuno M, Tamura M, Hashida M, Sezaki H. 1987. Effects of mitomycin C, 5-fluorouracil and cyclophosphamide on drug absorption, enzyme activities and mucosal lipid composition of intestine. J Pharmacobiodyn 10:321-329.
4. Rainsford KD, Stetsko PI, Sirko SP, Debski S. 2003. Gastrointestinal mucosal injury following repeated daily oral administration of conventional formulations of indometacin and other non-steroidal antiinflammatory drugs to pigs: A model for human gastrointestinal disease. J Pharm Pharmacol 55: 661-668.
5. Capel ID, Pinnock MH, Williams DC. 1979. An in vitro assessment of the effect of cytotoxic drugs upon the intestinal absorption of nutrients in rats. Eur J Cancer 15:127-131.
6. Lenzen S, Lortz S, Tiedge M. 1996. Effect of metformin on SGLT1, GLUT2, and GLUT5 hexose transporter gene expression in small intestine from rats. Biochem Pharmacol 51:893-896.
7. Roche AC, Bognel JC, Bognel C, Bernier JJ. 1970. Correlation between the histological changes and glucose intestinal absorption following a single dose of 5 fluorouracil. Digestion 3:195-212.
8. Yoshida A, Takata K, Kasahara T, Aoyagi T, Saito S, Hirano H. 1995. Immunohistochemical localization of Na(+)-dependent glucose transporter in the rat digestive tract. Histochem J 27:420-426.
9. Blakemore SJ, Aledo JC, James J, Campbell FC, Lucocq JM, Hundal HS. 1995. The GLUT5 hexose transporter is also localized to the basolateral membrane of the human jejunum. Biochem J 309: 7-12.
10. +/glucose cotransporter from rat jejunum. Biosci Biotechnol Biochem 61:979-983.
11. Lee WS, Kanai Y, Wells RG, Hediger MA. 1994. The high affinity Na+/glucose cotransporter. Reevaluation of function and distribution of expression. J Biol Chem 269:12032-12039.
12. +/glucose cotransporter. Nature 350:354-356.
13. Gould GW, Thomas HM, Jess TJ, Bell GI. 1991. Expression of human glucose transporters in Xenopus oocytes: Kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms. Biochemistry 30:5139-5145.
14. Mueckler M. 1994. Facultative glucose transporters. Eur J Biochem 219:713-725.
15. Parrilli G, Cuomo R, Nardone G, Maio G, Izzo CM, Budillon G. 1987. Investigation of intestine function during acute viral hepatitis using combined sugar oral loads. Gut 28:1439-1444.
16. Tavakkolizadeh A, Berger UV, Shen KR, Levitsky LL, Zinner MJ, Hediger MA, Ashley SW, Whang EE, Rhoads DB. 2001. Diurnal rhythmicity in intestinal SGLT-1 function, V(max), and mRNA expression topography. Am J Physiol Gastrointest Liver Physiol 280:G209-G215.
17. Tomimatsu T, Horie T. 2000. Enhanced absorption of 3-O-methyl-D-glucose through the small intestine of rats administered retinyl palmitate. Res Commun Mol Pathol Pharmacol 107:349-360.
18. Vinardell MP, Lopera MT. 1987. Jejunal and cecal 3-oxy-methyl-D-glucose absorption in chicken using a perfusion system in vivo. Comp Biochem Physiol A 86:625-627.
19. Fedorak RN, Thomson AB, Porter VM. 1991. Adaptation of intestinal glucose transport in rats with diabetes mellitus occurs independent of hyperphagia. Can J Physiol Pharmacol 69:1143-1148.
20. Levin RJ. 1968. Anatomical and functional changes of the small intestine induced by 5-fluorouracil. J Physiol 197:73P-74P.
21. Burns ER, Beland SS. 1984. Effect of biological time on the determination of the LD50 of 5-fluorouracil in mice. Pharmacology 28:296-300.
22. Gardner ML, Samson RR, Heading RC. 1978. Changes in absorptive and peptide hydrolase activities in rat small intestine after administration of 5-fluorouracil. Clin Sci Mol Med 54:411-418.
23. Hirata K, Horie T. 1999. Changes in intestinal absorption of 5-fluorouracil-treated rats. Pharmacol Toxicol 85:33-36.
24. Nakamaru M, Masubuchi Y, Narimatsu S, Awazu S, Horie T. 1998. Evaluation of damaged small intestine of mouse following methotrexate administration. Cancer Chemother Pharmacol 41:98-102.
25. Cheeseman CI, O'Neill D. 1998. Basolateral D-glucose transport activity along the crypt-villus axis in rat jejunum and upregulation induced by gastric inhibitory peptide and glucagon-like peptide-2. Exp Physiol 83:605-616.
26. Niinuma K, Takenaka O, Horie T, Kobayashi K, Kato Y, Suzuki H, Sugiyama Y. 1997. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: Comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3- pyridylmethyl)benzothiazole glucuronide. J Pharmacol Exp Ther 282:866-872.
27. +-ATPase: Molar and specific activity, protein determination. Methods Enzymol 156:105-115.
28. +-independent D-glucose transporter in the enterocyte basolateral membrane: Orientation and cytochalasin B binding characteristics. J Membr Biol 97: 259-266.
29. Tanii H, Horie T. 1999. Enhancement of glucose transport in small intestinal brush border membrane of retinol administered rat. Life Sci 64:1259-1264.
30. Uhing MR, Kimura RE. 1995. Active transport of 3-O-methyl-glucose by the small intestine in chronically catheterized rats. J Clin Invest 95:2799-2805.
31. Gouyon F, Caillaud L, Carriere V, Klein C, Dalet V, Citadelle D, Kellett GL, Thorens B, Leturque A, Brot-Laroche E. 2003. Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: A study in GLUT2-null mice. J Physiol 552:823-832.
32. Corpe CP, Basaleh MM, Affleck J, Gould G, Jess TJ, Kellett GL. 1996. The regulation of GLUT5 and GLUT2 activity in the adaptation of intestinal brush-border fructose transport in diabetes. Pflugers Arch 432:192-201.
33. +/glucose cotransporter by insulin. Biochem Mol Biol Int 37:33-38.
34. +/glucose cotransporter 1 mRNA levels is transcriptionally regulated. J Biol Chem 273:9510-9516.
35. Ferraris RP. 2001. Dietary and developmental regulation of intestinal sugar transport. Biochem J 360:265-276.
36. Burns ER, Beland SS. 1983. Induction by 5-fluorouracil of a major phase difference in the circadian profiles of DNA synthesis between the Ehrlich ascites carcinoma and five normal organs. Cancer Lett 20:235-239.
37. Miyamoto K, Hase K, Takagi T, Fujii T, Taketani Y, Minami H, Oka T, Nakabou Y. 1993. Differential responses of intestinal glucose transporter mRNA transcripts to levels of dietary sugars. Biochem J 295:211-215.
38. Miyamoto K, Hase K, Taketani Y, Minami H, Oka T, Nakabou Y, Hagihira H. 1991. Diabetes and glucose transporter gene expression in rat small intestine. Biochem Biophys Res Commun 181:1110-1117.