Wang-aldehyde resin as a recyclable support for the synthesis of α,α-disubstituted amino acid derivatives

Organic and Biomolecular Chemistry

Volumn 3, Issue 17, 2005, Pages 3188-3193

  Guinó, Meritxell ^a   Hii, King Kuok ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ALDEHYDES; ALKYLATION; AMINO ACIDS; ESTERS; IRRADIATION; MICROWAVES; REACTION KINETICS;

CYCLIC AMINO ACID ESTERS; HYDROXYBENZALDEHYDE; MERRIFIELD RESIN; MICROWAVE IRRADIATION;

RESINS;

ALDEHYDE; AMINO ACID; ESTER; RESIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; MICROWAVE RADIATION; RADIATION EXPOSURE; SYNTHESIS;

ALDEHYDES; AMINO ACIDS; ESTERS; MICROWAVES; MOLECULAR STRUCTURE; RESINS, SYNTHETIC;

EID: 25444504515     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b505881c     Document Type: Article

References (8)

1. M. J. O'Donnell, Acc. Chem. Res., 2004, 37. 506 and references therein.
2. M. J. O'Donnell, Aldrichimica Acta, 2001, 34, 3 and references therein.
3. B. Sauvagnat, K., Kulig, F. Lamaty, R. Lazaro and J. Martinez, J. Comb. Chem., 2000, 2, 134.
4. M. Guinó, E. Brule and Y. R. da Miguel, J. Comb. Chem., 2003, 5, 161.
5. H.-G. Park, M.-J. Kim, M.-K. Park, H.-J. Jung, J. Lee, Y.-J. Lee, B.-S. Jeong, J.-H. Lee, M. S. Yoo, J.-M. Ku and S.-S. Jew, Tetrahedron Lett., 2005, 46, 93.
6. H.-G. Park, M.-J. Kim, M.-K. Park, H.-J. Jung, J. Lee, Y.-J. Lee, S. Choi, Y.-J. Lee, B.-S. Jeong, J.-H. Lee, M.-S. Yoo, J.-M. Ku and S.-S. Jew, J. Org. Chem., 2005, 70, 1904.
7. Commercial samples of Wang-aldehyde resins (Novabiochem) were found to contain unspecified amounts of impurities and up to 0.8% of Cl (elemental analysis), which gave rise to unidentifiable side-products in the alkylation reactions.
8. D. L. Griffith, M. J. O'Donnell, R. S. Pottorf, W. L. Scott and J. A. Porco, Tetrahedron Lett., 1997, 38, 8821.