Changes in the expression of NO synthase isoforms after ozone: The effects of allergen exposure

Respiratory Research

Volumn 5, Issue , 2004, Pages

  Jang, An Soo ^a   Choi, Inseon S ^b   Lee, Jong Un ^b   Park, Sung Woo ^a   Lee, June Hyuk ^a   Park, Choon Sik ^a  

^a Soonchunhyang University College of Medicine   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Asthma; Nitric oxide synthase; Ozone

Indexed keywords

ALLERGEN; BIOLOGICAL MARKER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE SYNTHASE; NITRITE; OVALBUMIN; OZONE; SODIUM CHLORIDE; ISOPROTEIN;

AIR SAMPLING; AIRWAY OBSTRUCTION; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; LUNG FUNCTION TEST; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SENSITIZATION; UPREGULATION; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; BRONCHOSPASM; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYMOLOGY; LUNG; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ALLERGENS; ANIMALS; ASTHMA; BRONCHOCONSTRICTION; ENVIRONMENTAL EXPOSURE; FEMALE; LUNG; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE; OVALBUMIN; OZONE; PROTEIN ISOFORMS;

EID: 25444490106     PISSN: 1465993X     EISSN: None     Source Type: Journal    
DOI: 10.1186/1465-9921-5-5     Document Type: Article

References (28)

1. Arm JP, Lee TH: The pathobiology of bronchial asthma. Adv Immunol 1992, 51:323-382.
2. Moncada S, Palmer RMJ, Higgs EA: Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication. Biochem Pharmacol 1989, 11:1709-1715.
3. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991, 143:109-142.
4. Jang AS, Choi IS, Lee S, Seo JP, Yang SW, Park KO, Lee KY, Lee JU, Park CS, Park HS: Nitric oxide metabolites in induced sputum: a marker of airway inflammation in asthmatic subjects. Clin Exp Allergy 1999, 29:1136-1142.
5. Jang AS, Choi IS: Nitric oxide metabolites in patients with asthma: Induced sputum versus blood. Resp Med 1999, 93:912-918.
6. Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society: Health effects of outdoor air pollution. Am J Respir Crit Care Med 1996, 153:3-50.
7. Holtzman MJ, Fabbri LM, O'Byrne PM, Gold BD, Aizawa H, Walters EH, Alpert SE, Nadel JA: Importance of airway inflammation for hyperresponsiveness induced by ozone in dogs. Am Rev Respir Dis 1983, 127:686-690.
8. Murlas CG, Roum JH: Sequence of pathologic changes in the airway mucosa of guinea pigs during ozone-induced bronchial hyperreactivity. Am Rev Respir Dis 1985, 131:314-320.
9. Basha MA, Gross KB, Gwizdala CJ, Haidar AH, Popovich J: Bronchoalveolar lavage neutrophilia in asthmatic and healthy volunteers after controlled exposure to ozone and filtered purified air. Chest 1994, 106:1757-1765.
10. Seltzer J, Bigby BG, Stulbarg M, Holtzman MJ, Nadel JA, Ueki IF, Leikauf GD, Goetzl EJ, Boushey HA: O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol 1986, 60:1321-1326.
11. Koren HS, Devlin RB, Graham DE, Mann R, McGee MP, Horstman DH, Kozumbo WJ, Becker S, House DE, McDonnell WF: Ozone-induced inflammation in the lower airways of human subjects. Am Rev Respir Dis 1989, 139:407-415.
12. Jang AS, Choi IS, Lee JU: Neuronal nitric oxide synthase is associated with airway obstruction in BALB/c mice exposed to ozone. Respiration 2003, 70:95-9.
13. Brusselle GG, Kips JC, Tavernier JH, van der Heyden JG, Cuvelier CA, Pauwels RA, Bluethmann H: Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin Exp Allergy 1994, 24:73-80.
14. Jang AS, Choi IS, Kim SW, Song BC, Yeum CH, Jung JY: Airway obstruction after acute ozone exposure in BALB/c mice using barometric plethysmography. Kor J Intern Med 2003, 18:1-5.
15. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW: Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 1997, 156:766-775.
16. Johanson WG Jr, Pierce AK: A noninvasive technique for measurement of airway conductance in small animals. J Appl Physiol 1971, 30:146-150.
17. Pennock BE, Cox CP, Rogers RM, Cain WA, Wells JH: A noninvasive technique for measurement of changes in specific airway resistance. J Appl Physiol 1979, 46:399-406.
18. Brusselle GG, Kips JC, Tavernier JH, Van der Heyden JG, Cuvelier CA, Pauwels RA, Bluethmann H: Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin Exp Allergy 1994, 24:73-80.
19. Greenberg SS, Xie J, Spitzer JJ, Wang J, Lancaster J, Grishham MB, Powers DR, Giles TD: Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite. Life Sciences 1995, 57:1949-1961.
20. Gaston B, Drazen JM, Loscalzo J, Stamier JS: The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 1994, 149:538-551.
21. Barnes PJ: Nitric oxide and airways. Eur Respir J 1993, 6:163-165.
22. Haddad EB, Liu SF, Salmon M, Robichaud A, Barnes PJ, Chung KF: Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone. Eur J Pharmacol 1995, 293:287-290.
23. Chiba Y, Arimoto T, Yoshikawa T, Misawa M: Elevated nitric oxide synthase activity concurrent with antigen-induced airway hyperresponsiveness in rats. Exp Lung Res 2000, 26:535-549.
24. Liu SF, Haddad EB, Adcock I, Salmon M, Koto H, Gilbey T, Barnes PJ, Chung KF: Inducible nitric oxide synthase after sensitization and allergen challenge of Brown Norway rat lung. Br J Pharmacol 1997, 121:1241-1246.
25. Haddad EB, Liu SF, Salmon M, Robichaud A, Barnes PJ, Chung KF: Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone. Eur J Pharmacol 1995, 293:287-290.
26. Kobayashi H, Hataishi R, Mitsufuji H, Tanaka M, Jacobson M, Tomita T, Zapol WM, Jones RC: Antiinflammatory properties of inducible nitric oxide synthase in acute hyperoxic lung injury. Am J Respir Cell Mol Biol 2001, 24:390-397.
27. Fagan KA, Morrissey B, Fouty BW, Sato K, Harral JW, Morris KG Jr, Hoedt-Miller M, Vidmar S, McMurtry IF, Rodman DM: Upregulation of nitric oxide synthase in mice with severe hypoxia-induced pulmonary hypertension. Respir Res 2001, 2:306-313.
28. Barnes PJ: Nitric oxide and airway disease. Ann Med 1995, 27:389-393.