TELAML1-positive ALL. A discordant genotype

Cell Cycle

Volumn 4, Issue 8, 2005, Pages 997-998

  Den Boer, Monique L ^a   Evans, William E ^b   Pieters, Rob ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Childhood ALL; Drug resistance; Gene expression profiling; L asparaginase; TELAML1

Indexed keywords

ASPARAGINASE; ASPARTATE AMMONIA LIGASE; DAUNORUBICIN; PREDNISOLONE; PROTEIN; PROTEIN TELAM 1; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE LYMPHOCYTIC LEUKEMIA; CROSS RESISTANCE; DRUG SENSITIVITY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC CODE; GENOTYPE; NOTE; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

EID: 25444487701     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.8.1860     Document Type: Note

References (8)

1. Lugthart, S., Cheok, M.H., Den Boer, M.L., Yang, W., Holleman, A., Cheng, C., Pui, C.H., Relling, M.V., Janka-Schaub, G.E., Pieters, R., and Evans, W.E. (2005). Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. Cancer Cell 7, 375-386.
2. Ramakers-van Woerden, N.L., Pieters, R., Loonen, A.H., Hubeek, I., van Drunen, E., Beverloo, H.B., Slater, R.M., Harbott, J., Seyfarth, J., van Wering, E.R., Hahlen, K., Schmiegelow, K., Janka-Schaub, G.E., and Veerman, A.J.P. (2000). TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia. Blood 96, 1094-1099.
3. Stams, W.A.G., Den Boer, M.L., Beverloo, H.B., Meijerink, J.P.P., Stigter, R.L., van Wering, E.R., Janka-Schaub, G.E., Slater, R., and Pieters, R. (2003). Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL. Blood 101, 2743-2747.
4. Kaspers, G.J.L., Veerman, A.J.P., Pieters, R., Van Zantwijk, C.H., Smets, L.A., Van Wering, E.R., and Van der Does-van den Berg, A. (1997). In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia. Blood 90, 2723-2729.
5. Krejci, O., Starkova, J., Otova, B., Madzo, J., Kalinova, M., Hrusak, O., and Trka, J. (2004). Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells. Leukemia 18, 434-441.
6. Stams, W.A.G., Den Boer, M.L., Holleman, A., appel, I.M., Beverloo, H.B., van Wering, E.R., Janka-Schaub, G.E., Evans, WE., and Pieters, R. (2005). Asparagine synthetase expression is linked with L-asparaginase resistance in TELAML1 negative, but not in TELAML1 positive pediatric acute lymphoblastic leukemia. Blood 105, 4223-4225.
7. Fine, B.M., Kaspers, G.J., Ho, M., Loonen, A.H., and Boxer, L.M. (2005). A genome-wide view of the in vitro response to L-asparaginase in acute lymphoblastic leukemia. Cancer Res 65, 291-299.
8. Holleman, A., Cheok, M.H., Den Boer, M.L., Yang, W., Veerman, A.J.P., Kazemier, K.M., Pei, D., Cheng, C., Pui, C.H., Relling, M.V., Janka-Schaub, G.E., Pieters, R., and Evans, W.E. (2004). Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. N Engl J Med 351, 533-542.