Sequence motif upstream of the Hendra virus fusion protein cleavage site is not sufficient to promote efficient proteolytic processing

Virology

Volumn 341, Issue 1, 2005, Pages 130-140

  Craft Jr , Willie Warren ^a   Dutch, Rebecca Ellis ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cleavage; Fusion protein; Hendra; Henipavirus; Paramyxovirus; Post translational modifications

Indexed keywords

ALANINE; FURIN; MUTANT PROTEIN; VIRUS FUSION PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL SURFACE; CHIMERA; DNA FLANKING REGION; HENDRA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SUBSTITUTION REACTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; CRICETINAE; HENDRA VIRUS; MUTAGENESIS, SITE-DIRECTED; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION; TRYPSIN; VERO CELLS; VIRAL FUSION PROTEINS;

HENDRA VIRUS; HENIPAVIRUS; PARAMYXOVIRIDAE;

EID: 25444472562     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2005.07.004     Document Type: Article

References (40)

1. E.D. Anderson, L. Thomas, J.S. Hayflick, and G. Thomas Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant J. Biol. Chem. 268 33 1993 24887 24891
2. G. Bolt, and I.R. Pedersen The role of subtilisin-like proprotein convertases for cleavage of the measles virus fusion glycoprotein in different cell types Virology 252 2 1998 387 398
3. K.N. Bossart, L.F. Wang, B.T. Eaton, and C.C. Broder Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus Virology 290 1 2001 121 135
4. J.R. Carter, C.T. Pager, S.D. Fowler, and R.E. Dutch Role of N-linked glycosylation of the Hendra virus fusion protein J. Virol. 79 12 2005 7922 7925
5. K.B. Chua, W.J. Bellini, P.A. Rota, B.H. Harcourt, A. Tamin, S.K. Lam, T.G. Ksiazek, P.E. Rollin, S.R. Zaki, W. Shieh, C.S. Goldsmith, D.J. Gulber, J.T. Roehrig, B. Eaton, A.R. Gould, J. Olson, H. Field, R. Daniels, A.E. Ling, C.J. Peters, L.J. Anderson, and B.W. Mahy Nipah virus: a recently emergent deadly paramyxovirus Science 288 2000 1432 1435
6. K.B. Chua, C.L. Koh, P.S. Hooi, K.F. Wee, J.H. Khong, B.H. Chua, Y.P. Chan, M.E. Lim, and S.K. Lam Isolation of Nipah virus from Malaysian Island flying-foxes Microbes Infect. 4 2 2002 145 151
7. J.W. Dubay, S.R. Dubay, H.-J. Shin, and E. Hunter Analysis of the cleavage site of the human immunodeficiency virus type 1 glycoprotein: requirement of precursor cleavage for glycoprotein incorporation J. Virol. 69 1995 4675 4682
8. W. Garten, S. Hallenberger, D. Ortmann, W. Schafer, M. Vey, H. Angliker, E. Shaw, and H.D. Klenk Processing of viral glycoproteins by the substilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones Biochimie 76 1994 217 225
9. R.L. Glickman, R.J. Syddall, R.M. Iorio, J.P. Sheehan, and M.A. Bratt Quantitative basic residue requirements in the cleavage-activation site of the fusion glycoprotein as a determinant of virulence for Newcastle disease virus J. Virol. 62 1988 354 356
10. S. Hallenberger, V. Bosch, H. Angliker, E. Shaw, H.D. Klenk, and W. Garten Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160 Nature 360 6402 1992 358 361
11. B.H. Harcourt, A. Tamin, T.g. Ksiazek, P.E. Rollin, L.J. Anderson, W.J. Bellini, and P.A. Rota Molecular characterization of Nipah virus, a newly emergent paramxyovirus Virology 271 2000 334 349
12. M. Homma Trypsin action on the growth of Sendai virus in tissue culture cells: I. Restoration of the infectivity for L cells by direct action of trypsin on L cell-borne Sendai virus J. Virol. 8 5 1971 619 629
13. M. Homma, and S. Tamagawa Restoration of the fusion activity of L cell-borne Sendai virus by trypsin J. Gen. Virol. 19 1973 423 426
14. H. Kido, Y. Yokogoshi, K. Sakai, M. Tashiro, Y. Kishino, A. Fukutomi, and N. Katunuma Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells J. Biol. Chem. 267 1992 13573 13579
15. W.B. Klimstra, H.W. Heidner, and R.E. Johnston The furin protease cleavage recognition sequence of Sindbis Virus PE2 can mediate virion attachment to cell surface heparan sulfate J. Virol. 73 8 1999 6299 6306
16. R.A. Lamb Paramyxovirus fusion: a hypothesis for changes Virology 197 1993 1 11
17. R.A. Lamb, and D. Kolakofsky Paramyxoviridae: the viruses and their replication D.M. Knipe P.M. Howley Fields Virology 4th ed. 2001 Lippincott-Raven Press New York 1305 1340
18. Z. Li, T. Sergel, E. Razvi, and T. Morrison Effect of cleavage mutants on syncytium formation directed by the wild-type fusion protein of Newcastle disease virus J. Virol. 72 1998 3789 3795
19. W.P. Michalski, G. Crameri, L. Wang, B.J. Shiell, and B. Eaton The cleavage activation and sites of glycosylation in the fusion protein of Hendra virus Virus Res. 69 2 2000 83 93
20. M. Moll, S. Diederich, H.D. Klenk, M. Czub, and A. Maisner Ubiquitous activation of the Nipah virus fusion protein does not require a basic amino acid at the cleavage site J. Virol. 78 2004 9705 9712
21. K. Murray, P. Selleck, P. Hooper, A. Hyatt, A. Gould, L. Gleeson, H. Westbury, and L.e.a. Hiley A morbillivirus that caused fatal disease in horses and humans Science 268 1995 94 97
22. Y. Nagai, and H.-D. Klenk Activation of precursors to both glycoproteins of Newcastle disease virus by proteolytic cleavage Virology 77 1977 125 134
23. H. Niwa, K. Yamamura, and J. Miyazaki Efficient selection for high-expression transfectants by a novel eukaryotic vector Gene 108 1991 193 200
24. J.D. O'Sullivan, A.M. Allworth, D.L. Paterson, T.M. Snow, R. Boots, L.J. Gleeson, A.R. Gould, A.D. Hyatt, and J. Bradfield Fatal encephalitis due to novel paramyxovirus transmitted from horses Lancet 349 9045 1997 93 95
25. Pager, C.T., Dutch, R.E., in press. Cathepsin L is involved in proteolytic processing of the Hendra virus fusion protein. J. Virol.
26. C.T. Pager, M.A. Wurth, and R.E. Dutch Subcellular localization and calcium and pH requirements for proteolytic processing of the Hendra virus fusion protein J. Virol. 78 17 2004 9154 9163
27. R.G. Paterson, and R.A. Lamb Ability of the hydrophobic fusion-related external domain of a paramyxovirus F protein to act as a membrane anchor Cell 48 1987 441 452
28. R.G. Paterson, and R.A. Lamb The molecular biology of influenza viruses and paramyxoviruses A. Davidson R.M. Elliott Molecular Virology: A Practical Approach 1993 IRL Oxford Univ. Press Oxford 35 73
29. R.G. Paterson, M.A. Shaughnessy, and R.A. Lamb Analysis of the relationship between cleavability of a paramyxovirus fusion protein and length of the connecting peptide J. Virol. 63 1989 1293 1301
30. R.G. Paterson, S.M. Thomas, and R.A. Lamb Specific nontemplated nucleotide addition to a simian virus 5 mRNA: prediction of a common mechanism by which unrecognized hybrid P-cysteine-rich proteins are encoded by paramyxovirus "P" genes D. Kolakofsky B.W.J. Mahy Genetics and Pathogenicity of Negative Strand Viruses 1989 Elsevier London 232 245
31. R. Rott, H. Klenk, Y. Nagai, and M. Tashiro Influenza viruses, cell enzyme, and pathogenicity Am. J. Respir. Crit. Care Med. 152 1995 S16 S19
32. K. Sakai, T. Kohri, M. Tashiro, Y. Kishino, and H. Kido Sendai virus infection changes the subcellular localization of tryptase Clara in rat bronchiolar epithelial cells Eur. Respir. J. 7 1994 686 692
33. A. Scheid, and P.W. Choppin Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus Virology 57 1974 475 490
34. D. Senne, B. Panigrahg, Y. Kawahira, J. Pearson, J. Suss, M. Lipkind, H. Kida, and R. Webster Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avain influenza viruses; amino aicd sequence at the HA cleavage site as a marker of pathogenicity potential Avian Dis. 40 2 1996 425 437
35. R.J. Sugrue, C. Brown, G. Brown, J. Aitken, and H.W.M. Rixon Furin cleavage of the respiratory syncytial virus fusion protein is not a requirement for its transport to the surface of virus-infected cells J. Gen. Virol. 82 2001 1019 1026
36. M. Tashiro, J.T. Seto, S. Choosakul, H. Hegemann, H.-D. Klenk, and R. Rott Changes in specific cleavability of the Sendai virus fusion protein: implications for pathogenicity in mice J. Gen. Virol. 73 1992 1575 1579
37. V.E. Volchkov, H. Feldmann, V.A. Volchkova, and H.D. Klenk Processing of the Ebola virus glycoprotein by the proprotein convertase furin Proc. Natl. Acad. Sci. U.S.A. 95 10 1998 5762 5767
38. L.F. Wang, M. Yu, E. Hansson, L.I. Pritchard, B. Shiell, W.P. Michalski, and B.T. Eaton The exceptionally large genome of Hendra virus: support for creation of a new genus within the family Paramyxoviridae J. Virol. 74 21 2000 9972 9979
39. G. Yamshchikov, R. GD, M. Vey, and R.W. Compans Assembly of SIV virus-like particles containing envelope proteins using a baculovirus expression system Virology 214 1 1995 50 58
40. P.L. Young, K. Halpin, P.W. Selleck, H. Field, J.L. Gravel, M.A. Kelly, and J.S. Mackenzie Serologic evidence for the presence in Pteropus bats of a paramyxovirus related to equine morbillivirus Emerg. Infect Dis. 2 3 1996 239 240