1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines: Synthesis and in vitro antiamoebic activities

European Journal of Medicinal Chemistry

Volumn 40, Issue 9, 2005, Pages 935-942

  Abid, Mohammad ^a   Azam, Amir ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

Entamoeba histolytica; Mannich base; Pyrazoline; Thiocarbamoyl; Thiosemicarbazide

Indexed keywords

1 [(3 PHENYL 4,5 DIHYDRO 1H PYRAZOL 1 YL)THIOCARBAMOYL] 4 (PHENYLMETHYL)PIPERAZINE; 1 [[3 (3 BROMOPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 (PHENYLMETHYL)PIPERAZINE; 1 [[3 (3 BROMOPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 METHYLPIPERIDINE; 1 [[3 (3 BROMOPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 PHENYLPIPERAZINE; 1 [[3 (3 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 (PHENYLMETHYL)PIPERAZINE; 1 [[3 (3 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 METHYLPIPERIDINE; 1 [[3 (3 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]THIOCARBAMOYL] 4 PHENYLPIPERAZINE; 3 (3 BROMOPHENYL) N [(2 CHLOROPHENYL)METHYL] 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 BROMOPHENYL) N CYCLOHEXYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 BROMOPHENYL) N CYCLOOCTYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 BROMOPHENYL) N CYCLOPENTYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 CHLOROPHENYL) N [(2 CHLOROPHENYL)METHYL] 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 CHLOROPHENYL) N CYCLOHEXYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 CHLOROPHENYL) N CYCLOOCTYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 3 (3 CHLOROPHENYL) N CYCLOPENTYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; 4 METHYL 1 [(3 PHENYL 4,5 DIHYDRO 1H PYRAZOL 1 YL)THIOCARBAMOYL]PIPERIDINE; 4 PHENYL 1 [(3 PHENYL 4,5 DIHYDRO 1H PYRAZOL 1 YL)THIOCARBAMOYL]PIPERAZINE; ANTIAMEBIC AGENT; MANNICH BASE; METRONIDAZOLE; N [(2 CHLOROPHENYL)METHYL] 3 PHENYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; N CYCLOHEXYL 3 PHENYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; N CYCLOOCTYL 3 PHENYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; N CYCLOPENTYL 3 PHENYL 4,5 DIHYDRO 1H PYRAZOLE 1 THIOCARBOXAMIDE; PHENYL GROUP; PYRAZOLINE DERIVATIVE; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; MANNICH REACTION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; ANTIPROTOZOAL AGENTS; ENTAMOEBA HISTOLYTICA; MAGNETIC RESONANCE SPECTROSCOPY; METRONIDAZOLE; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PYRAZOLES; SPECTROPHOTOMETRY, INFRARED;

EID: 25444451854     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.03.015     Document Type: Article

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