Safety features of budesonide inhalation suspension in the long-term treatment of asthma in young children

Advances in Therapy

Volumn 22, Issue 3, 2005, Pages 198-207

  Leflein, Jeffrey G ^a,e   Baker, James W ^b   Eigen, Howard ^c   Lyzell, Ewa ^d   McDermott, Lawrence ^d  

^a Allergy and Immunology Associates of Ann Arbor PC   (United States)

^b Allergy Associates PC   (United States)

^c RILEY HOSPITAL FOR CHILDREN   (United States)

^d ASTRAZENECA   (United Kingdom)

^e NONE   (United States)

Author keywords

Budesonide inhalation suspension; Long term safety; Pediatric asthma

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; CROMOGLYCATE DISODIUM; FLUTICASONE PROPIONATE; IPRATROPIUM BROMIDE; METHYLXANTHINE DERIVATIVE; SALMETEROL XINAFOATE;

ARTICLE; ASTHMA; BACTERIAL INFECTION; BRONCHITIS; BRONCHOSPASM; CHOLELITHIASIS; CLINICAL TRIAL; CONJUNCTIVITIS; DEHYDRATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FEVER; HEADACHE; HUMAN; INJURY; LONG TERM CARE; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OPEN STUDY; OTITIS MEDIA; PHARYNGITIS; PHYSICAL EXAMINATION; PNEUMONIA; PRESCHOOL CHILD; RASH; RESPIRATORY TRACT INFECTION; RHINITIS; SCHOOL CHILD; SINUSITIS; SUSPENSION; VIRUS INFECTION; VOMITING;

EID: 25444433618     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02849929     Document Type: Article

References (13)

1. National Asthma Education and Prevention Program. Expert panel report: guidelines for the diagnosis and management of asthma. Update on selected topics - 2002. J Allergy Clin Immunol. 2002;110(5 suppl):S141-S219.
2. Agertoft L, Pedersen S. Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med. 1994;88:373-381.
3. Leone FT, Fish JE, Szefler SJ, West SL for the Expert Panel on Corticosteroid Use. Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma. Chest. 2003;124:2329-2340.
4. American Academy of Allergy, Asthma, and Immunology, National Heart, Lung, and Blood Institute, National Asthma Education and Prevention Program, and American Academy of Pediatrics. Pediatric Asthma: Promoting Best Practice. Guide for Managing Asthma in Children. Milwaukee, Wis: American Academy of Allergy, Asthma, and Immunology, 2004.
5. Pulmicort Respules® (budesonide inhalation suspension) Product Information. AstraZeneca LP, Wilmington, Del, 2003.
6. Leflein JG, Gawchik SM, Galant SP, et al. Safety of budesonide inhalation suspension (Pulmicort Respules) after up to 52 weeks of treatment in infants and young children with persistent asthma. Allergy Asthma Proc. 2001;22:359-366.
7. Scott MB, Skoner DP. Short-term and long-term safety of budesonide inhalation suspension in infants and young children with persistent asthma. J Allergy Clin Immunol. 1999;104:200-209.
8. Leflein JG, Szefler SJ, Murphy KR, et al. Nebulized budesonide inhalation suspension compared with cromolyn sodium nebulizer solution for asthma in young children: results of a randomized outcomes trial. Pediatrics. 2002;109:866-872.
9. Baker JW, Mellon M, Wald J, Welch M, Cruz-Rivera M, Walton-Bowen K. A multiple-dosing, placebo-controlled study of budesonide inhalation suspension given once or twice daily for treatment of persistent asthma in young children and infants. Pediatrics. 1999;103:414-421.
10. Kemp JP, Skoner DP, Szefler SJ, Walton-Bowen K, Cruz-Rivera M, Smith JA. Once-daily budesonide inhalation suspension for the treatment of persistent asthma in infants and young children. Ann Allergy Asthma Immunol. 1999;83:231-239.
11. Shapiro G, Mendelson L, Kraemer MJ, Cruz-Rivera M, Walton-Bowen K, Smith JA. Efficacy and safety of budesonide inhalation suspension (Pulmicort Respules) in young children with inhaled steroid-dependent, persistent asthma. J Allergy Clin Immunol. 1998;102:789-796.
12. Agertoft L, Pedersen S. Effect of long-term treatment with inhaled budesonide on adult height in children with asthma. N Engl J Med. 2000;343:1064-1069.
13. Childhood Asthma Management Program Research Group. Long term effects of budesonide or nedocromil in children with asthma. N Engl J Med. 2000;343:1054-1063.