Virtual screening for inhibitors of human aldose reductase

Proteins: Structure, Function and Genetics

Volumn 55, Issue 4, 2004, Pages 814-823

  Kraemer, Oliver ^a,c   Hazemann, Isabelle ^b   Podjarny, Alberto D ^b   Klebe, Gerhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

Author keywords

Diabetes; Docking; DrugScore; Pharmacophore

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; BTB 02809; IDD 594; JFD 00882; UNCLASSIFIED DRUG; ZOPOLRESTAT;

ARTICLE; COMPUTER ANALYSIS; CONCENTRATION RESPONSE; CRYSTAL STRUCTURE; DRUG SCREENING; ENZYME INHIBITOR INTERACTION; INHIBITION KINETICS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DATABASE; STRUCTURE ACTIVITY RELATION;

ACETATES; ALDEHYDE REDUCTASE; ANIONS; BINDING SITES; COMPUTER SIMULATION; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PROTEIN BINDING; THIOCARBAMATES;

EID: 2542631937     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20057     Document Type: Article

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