The Lipopeptide, Pam3Cys-Ser-(Lys)4: An Alternative Adjuvant to Freund's Adjuvant for the Immunisation of Chicken to Produce Egg Yolk Antibodies

Alternatives to Laboratory Animals

Volumn 25, Issue 2, 1997, Pages 173-181

  Erhard, Michael H ^a   Schmidt, Peter ^a   Hofmann, Andrea ^a   Bergmann, Josefine ^a   Mittermeier, Peter ^a   Kaufmann, Pia ^a   Wiesmüller, Karl Heinz ^b   Bessler, Wolfgang G ^c   Lösch, Uli ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Adjuvant; Antibody titre; Chicken egg yolk antibodies; Freund's adjuvant; Histopathology; IgY levels; Immunoglobulin Y (IgY); Lipopeptide

Indexed keywords

ANIMALIA; CORONAVIRUS; ESCHERICHIA COLI; GALLUS GALLUS; ROTAVIRUS;

EID: 2542571188     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Bar-Joseph, M. & Malkinson, M. (1980). Hen egg yolk as a source of antiviral antibodies in the enzyme-linked immunosorbent assay (ELISA); a comparison of two plant viruses. Journal of Virological Methods 1, 179-183.
2. Gottstein, B. & Hemmeler, E. (1985). Egg yolk immunoglobulin Y as an alternative antibody in the serology of ecchinococcosis. Zeitschrift für Parasitenkunde 71, 273-276.
3. Larsson, A., Karlsson-Parra, A. & Sjöquist, J. (1991). Use of chicken antibodies in enzyme immunoassays to avoid interference by rheumatoid factors. Clinical Chemistry 37, 411-414.
4. Ntakarutimana, V., Demedts, P. & van Sande, M. (1992). A simple and economical strategy for downstream processing of specific antibodies to human transferrin from egg yolk. Journal of Immunological Methods 153, 133-140.
5. Sturmer, A.M., Driscoll, D.P. & Jackson-Matthews, D.E. (1992). A quantitative immunoassay usíng chicken antibodies for detection of native and recombinant α-amidating enzyme. Journal of Immunological Methods 146, 105-110.
6. Larsson, A. & Lindahl, T. (1993). Chicken antiprotein G for the detection of small amounts of protein G. Hybridoma 12, 143-147.
7. Wiedemann, V., Linckh, E., Kühlmann, R., Schmidt, P. & Losch, U. (1991). Chicken egg antibodies for prophylaxis and therapy of infectious intestinal diseases. V. In vivo studies on protective effects against Escherichia coli diarrhoea in pigs. Journal of Veterinary Medicine Series B 38, 283-291.
8. Ikemori, Y., Kuroki, M , Peralta, R & Yokoyama, Y. (1992) Protection of neonatal calves against fatal enteric colibacillosis by administration of egg powder from hens immunized with K99-pilated enterotoxic Escherichia coli. American Journal of Veterinary Research 53, 2005-2008.
9. Yokoyama, H.R., Peralta, R.C., Diaz, R., Sendo, S., Ikemori, Y. & Kodama, Y. (1992). Passive protection effect of chicken egg yolk immunoglobins against experimental enterotoxic Escherichia coli infection in neonatal piglets. Infectious Immunity 60, 998-1007.
10. Erhard, M.H., Kellner, J., Eichelberger, J. & Lösch, U, (1993). Neue Möglichkeiten in der oralen. Immunprophylaxe des Kalbes: ein Feldversuch mit spezifischen Eiantikörpern (New aspects in oral immunoprophylaxis for the prevention of infectious diarrhoea of newborn calves: a field study with specific antibodies). Berliner und Münchner Tierärztliche Wochenschrift 106, 383-387.
11. Kellner, J., Erhard, M.H., Renner, M. & Lösch, U. (1994). Therapeutischer Einsatz von spezifischen Eiantikorpern bei Saugferkeldurchfall: ein Feldversuch (A field trial of the treatment of diarrhoea in piglets with specific antibodies). Tierärztliche Unschau 49, 31-34.
12. Ozpinar, H., Erhard, M.H., Aytug, N., Ozpinar, A., Baklaci, C , Karamüptüglu, S., Hofmann, A. & Lösch, U. (1996). Dose-dependent effects of specific egg-yolk antibodies on diarrhoea of newborn calves. Preventive Veterinary Medicine 27, 67-73.
13. Erhard, M.H., Bergmann, J., Renner, M., Hofmann, A. & Heinrïtzi, K. (1996). Prophylaktische Wirkung von spezifischen Dotterantikörpern bei Escherichia coli K88 (F4)-bedingten Durchfallerkrankungen von Absatzferkeln (Prophylactic effect of specific egg yolk antibodies in diarrhoea of weaned piglets caused by Escherichia coli K88 [F4]). Journal of Veterinary Medicine Series A 43, 217-223.
14. Freund, J. & McDermott, K. (1942). Sensitisation to horse serum by means of adjuvants. Proceedings of the Society for Experimental Biology and Medicine 49, 548-553.
15. Hillemann, M.R. (1966). Critical appraisal of emulsified oil adjuvants applied to viral vaccines. Progress in Medical Virology 8, 131-182.
16. Murray, R , Cohen, P. & Hardegree, M C (1972). Mineral oil adjuvants: biological and chemical studies. Annals of Allergy 30, 146-151
17. Altmann, A. & Dixon, F.J. (1989). Immunomodifiers in vaccines. Advanced Veterinary Science of Comparative Medicine 33, 301-343
18. Wiedemann, F., Link, R., Pumpe, K., Jacobshagen, U., Schaefer, H.E., Wiesmüller, K-H., Hummel, R-P., Jung, G, Bessler, W.G. & Böltz, T. (1991). Histopathological studies on the local reactions induced by complete Freund's adjuvant (CFA), bacterial lipopolysaccharide (LPS), and synthetic lipopeptide (P3C) conjugates. Journal of Pathology 164, 265-271.
19. Wanke, R., Schmidt, P., Erhard, M.H., Sprick-Sanjose Messing, A., Stangassinger, M., Schmahl, W. & Hermanns, W. (1996). Freundsches komplettes Adjuvans beim Huhn: effiziente Immunstimulation bei gravierender lokaler inflammatorischer Reaktion (Freunds complete adjuvant in the chicken: efficient immunostimulation but severe local inflammation). Journal of Veterinary Medicine Series A 43, 243-253.
20. Wiesmüller, K-H., Bessler, W.G. & Jung, G. (1983). Synthesis of the mitogenic S-(2,3-bis[palmitolyloxy]propyl)N-palmitoyl-pentapeptide from Escherichia coli lipoprotein. Zeitschrift für Physiologische Chemie, Hoppe-Seyler 364, 593-606.
21. Reitermann, A., Metzger, J., Wiesmüller, K-H., Jung, G. & Bessler, W.G. (1989). Lipopeptide derivates of bacterial lipoprotein constitute potent immune adjuvants combined or covalently coupled to antigen or hapten. Biological Chemistry, Hoppe-Seyler 370, 343-352.
22. Kellner, J., Erhard, M.H., Schranner, I. & Lösch, U. (1992). The influence of various adjuvants on antibody synthesis following immunization with an hapten. Biological Chemistry, Hoppe-Seyler 373, 51-55.
23. Suttnar, J., Hrkal, Z. & Vodrazka, Z. (1977). Affinity chromatography of serum haemopexin. Journal of Chromatography 131, 453-457.
24. Suter, M. (1982). A modified ELISA technique for anti-hapten antibodies. Journal of Immunological Methods 78, 173-190.
25. Schmidt, P., Kühlmann, R. & Lösch, U. (1988). A competitive enzyme immunoassay for detection and quantification of organophosphorus compounds. Zeitschrift für Naturforschung 46, C167-C172.
26. Erhard, MH., Von Quistorp, I., Schranner, I., Jüngling, A., Kaspers, B., Schmidt, P. & Kühlmann, R (1992). Development of specific enzyme-linked immunosorbent antibody systems for the detection of chicken immunoglobulins G, M and A using monoclonal antibodies. Poultry Science 71, 302-310.
27. Kowalczyk, K., Daiss, J , Halpern, J. & Roth, T.F. (1985). Quantification of maternal-fetal IgG transport in the chicken. Immunology 54, 755-762.
28. Schade, R., Staak, C., Hendriksen, C., Erhard, M.H., Hugl, H., Koch, G., Larsson, A., Pollmann, W., van Regenmortel, M., Rijke, E., Spielmann, H., Steinbusch, H. & Straughan, D. (1996). The production of avian (egg yolk) antibodies: IgY. The report and recommendations of ECVAM workshop 21. ATLA 24, 925-934.