Synthesis of 2-N-acylamino-4-arylthiazole-5-acetic acids/esters for their anti-inflammatory and analgesic activities

Asian Journal of Chemistry

Volumn 16, Issue 1, 2004, Pages 179-182

  Attimarad, Mahesh ^a   Somasekhar, Vanita ^a,b   Mohan, S ^a,b  

^a AL AMEEN COLLEGE OF PHARMACY   (India)

^b PES COLLEGE OF PHARMACY   (India)

Author keywords

Anti inflammatory and Analgesic Activity; Synthesis; Thiazole acetic acids

Indexed keywords

4 (2 THIENYL) 2 AMINOTHIAZOLE 5 ACETIC ACID; ACETIC ACID DERIVATIVE; ACETIC ANHYDRIDE; ETHYL 2 ACETYLAMINO 4 (2 THIENYL)THIAZOLE 5 ACETATE; ETHYL 2 SUCCINOYLAMINO 4 (2 THIENYL)THIAZOLE 5 ACETATE; ETHYL 4 (2 THIENYL) 2 AMINOTHIAZOLE 5 ACETATE; SUCCINIC ANHYDRIDE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RAT;

EID: 2542554961     PISSN: 09707077     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. C.S. Lakshmeesha and G. Bagavant, "Synthesis and pharmacological activity of potential anti - inflammatory agents-succinamic acid derivatives", M. Pharm. Thesis, Bangalore University (1997).
2. Chem. Abstr., 122, 188044g (1995).
3. M. Attimarad and G. Bagavant, Indian J. Pharm. Sci., 61, 152 (1999).
4. W. Hepworth, B.B. Newbould, D.S. Platt and G.J. Stacey, Nature, 221, 582 (1969).
5. A. Muresan, M. Coman, M. Kori and L. Smithi, Clujul Med., 59, 262 (1986) ; Chem. Abstr., 106, 149101y (1987).
6. A. Muresan, M. Coman, M. Kori and L. Smithi, Clujul Med., 59, 262 (1986) ; Chem. Abstr., 106, 149101y (1987).
7. S.A. Pafil and G. Bagavant, J. Indian Chem. Soc., 71, 205 (1994).
8. C.A. Winter, E.P. Riley and G.W. Nass, Proc. Soc. Expt. Biol. Med., 111, 554 (1962).
9. P.S. Prem, Y.S. Ajit, Seshagiri Rao, K.V. Ravindra and R.S. Dilbag, Expt. Clin. Pharmacol., 5, 60 (1985).