Synthetic peptide derived from α-fetoprotein inhibits growth of human breast cancer: Investigation of the pharmacophore and synthesis optimization

Journal of Peptide Research

Volumn 63, Issue 5, 2004, Pages 409-419

  DeFreest, L A ^a   Mesfin, F B ^a   Joseph, L ^a   McLeod, D J ^a   Stallmer, A ^a   Reddy, S ^a   Balulad, S S ^a   Jacobson, H I ^b   Andersen, T T ^a   Bennett, J A ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b ALBANY MEDICAL CENTER   (United States)

Author keywords

fetoprotein; Breast cancer; Estrogen; Head to tail cyclization; Synthetic peptide

Indexed keywords

ALANINE; ALPHA FETOPROTEIN; AMINO ACID; ANTIESTROGEN; ASPARAGINE; ASPARTIC ACID; ESTROGEN; ESTROGEN RECEPTOR; GLUTAMIC ACID; GLUTAMINE; HYDROXYPROLINE; IMINO ACID; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; PROLINE; SERINE; SYNTHETIC PEPTIDE; THREONINE; TYROSINE; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOM; BINDING SITE; BIOASSAY; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG PURIFICATION; DRUG SAFETY; DRUG SCREENING; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; FEMALE; HUMAN; INHIBITION KINETICS; MOLECULAR DYNAMICS; MOLECULE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PHARMACOPHORE; PREGNANCY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SOLID; STIMULATION; TUMOR XENOGRAFT; UTERUS GROWTH;

ALPHA-FETOPROTEINS; AMINO ACID SEQUENCE; ANIMALS; BREAST NEOPLASMS; FEMALE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; RECEPTORS, ESTROGEN; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 2542553376     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2004.00139.x     Document Type: Article

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