Protective role of interleukin-6 during Yersinia enterocolitica infection is mediated through the modulation of inflammatory cytokines

Infection and Immunity

Volumn 72, Issue 6, 2004, Pages 3561-3570

  Dube, Peter H ^a   Handley, Scott A ^a,b   Lewis, James ^a   Miller, Virginia L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; IMMUNOMODULATION; INFLAMMATION; NONHUMAN; PERITONEUM MACROPHAGE; PHENOTYPE; PRIORITY JOURNAL; TH1 CELL; YERSINIA ENTEROCOLITICA; YERSINIOSIS;

ANIMALS; CYTOKINES; GENE EXPRESSION REGULATION; INFLAMMATION; INTERLEUKIN-6; LIVER; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; PANCREAS; VIRULENCE; YERSINIA ENTEROCOLITICA; YERSINIA INFECTIONS;

EID: 2542552037     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.6.3561-3570.2004     Document Type: Article

References (31)

1. Autenrieth, I. B., M. Beer, E. Bohn, S. H. E. Kaufmann, and J. Heesemann. 1994. Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: an essential role for gamma interferon. Infect. Immun. 62:2590-2599.
2. Autenrieth, I. B., and J. Heesemann. 1992. In vivo neutralization of tumor necrosis factor-alpha and interferon-gamma abrogates resistance to Yersinia enterocolitica infection in mice. Med. Microbiol. Immunol. 181:333-338.
3. Autenrieth, I. B., V. Kempf, T. Sprinz, S. Preger, and A. Schnell. 1996. Defense mechanisms in Peyer's patches and mesenteric lymph nodes against Yersinia enterocolitica involve integrins and cytokines. Infect. Immun. 64: 1357-1368.
4. Autenrieth, I. B., A. Tingle, A. Reske-Kunz, and J. Heesemann. 1992. T lymphocytes mediate protection against Yersinia enterocolitica in mice: characterization of murine T-cell clones specific for Y. enterocolitica. Infect. Immun. 60:1140-1149.
5. Beuscher, H. U., U. P. Rausch, I. G. Otterness, and M. Röllinghoff. 1992. Transition from interleukin 1β (IL-1β) to IL-1α production during maturation of inflammatory macrophages in vivo. J. Exp. Med. 175:1793-1797.
6. Bottone, E. J. 1997. Yersinia enterocolitica: the charisma continues. Clin. Microbiol. Rev. 10:257-276.
7. Buzoni-Gatel, D., H. Debbabi, V. Martin, A. C. LePage, J. D. Schwartzman, and L. H. Kasper. 2001. Murine ileitis after intracellular parasite infection is controlled by TGF-β producing intraepithelial lymphocytes. Gastroenterology 120:914-924.
8. Carter, P. B. 1975. Oral Yersinia enterocolitica infection of mice. Am. J. Pathol. 81:703-705.
9. Carter, P. B. 1975. Pathogenicity of Yersinia enterocolitica for mice. Infect. Immun. 11:164-170.
10. Carter, P. B., and F. M. Collins. 1974. Experimental Yersinia enterocolitica infection in mice: kinetics of growth. Infect. Immun. 9:851-857.
11. Carter, P. B., and F. M. Collins. 1974. The route of enteric infection in normal mice. J. Exp. Med. 139:1189-1203.
12. Dalrymple, S. A., L. A. Lucian, R. Slattery, T. McNeil, D. M. Aud, S. Fuchino, F. Lee, and R. Murray. 1995. Interleukin-6 deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia. Infect. Immun. 63:2262-2268.
13. Diehl, S., J. Anguita, A. Hoffmeyer, T. Zapton, J. N. Ihle, E. Fikrig, and M. Rincon. 2000. Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity 13:805-815.
14. Dube, P. H., P. A. Revell, D. D. Chaplin, R. G. Lorenz, and V. L. Miller. 2001. A role for IL-1α in inducing pathologic inflammation during bacterial infection. Proc. Natl. Acad. Sci. USA 98:10880-10885.
15. Hein, J., A. Sing, M. S. Di Genaro, and I. B. Autenrieth. 2001. Interleukin-12 and interleukin-18 are indispensable for protective immunity against enteropathogenic Yersinia. Microb. Pathog. 4:195-199.
16. Hurst, S. M., T. S. Wilkinson, R. M. McLoughlin, S. Jones, S. Horiuchi, N. Yamamoto, S. Rose-John, G. M. Fuller, N. Topely, and S. A. Jones. 2001. IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14:705-714.
17. Jordan, M., I. Otterness, R. Ng, A. Gessner, M. Rollinghoff, and H. U. Beuscher. 1995. Neutralization of endogenous IL-6 suppresses induction of IL-1 receptor antagonist. J. Immunol. 154:4081-4090.
18. Kampik, D., R. Schulte, and I. B. Autenrieth. 2000. Yersinia enterocolitica Invasin protein triggers differential production of interleukin-1, interleukin-8, monocyte chemoattractant protein 1, granulocyte-macrophage colony stimulating factor, and tumor necrosis factor alpha in epithelial cells: implications for understanding the early cytokine networks in Yersinia infections. Infect. Immun. 68:2484-2492.
19. + mutant. Gene 136:271-275.
20. Kishimoto, T. 1987. The biology of interleukin-6. Blood 74:1-10.
21. Koj, A. 1985. The acute phase response to injury and infection, p. 139-144. Elsevier, Amsterdam, The Netherlands.
22. Kopf, M., H. Baumann, G. Freer, M. Freudenberg, M. Lamers, T. Kishimoto, R. Zinkernagel, H. Bleuthmann, and G. Kohler. 1994. Impaired immune and acute-phase responses in interleukin-6 deficient mice. Nature 368:339-342.
23. Ladel, C. H., C. Blum, A. Dreher, K. Reifenberg, M. Kopf, and S. H. E. Kaufmann. 1997. Lethal tuberculosis in interleukin-6-deficient mice. Infect. Immun. 65:4843-4849.
24. Letterio, J. J., and A. B. Roberts. 1998. Regulation of immune responses by TGF-β. Annu. Rev. Immunol. 16:137-161.
25. Perry, R. D., and J. D. Fetherston. 1997. Yersinia pestis: etiologic agent of plague. Clin. Microbiol. Rev. 10:35-66.
26. Reed, L. J., and H. Muench. 1938. A simple method for estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
27. Schindler, R., J. Mancilla, S. Endres, R. Ghorbani, S. C. Clark, and C. A. Dinarello. 1990. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 75:40-44.
28. Shull, M. M., I. Ormsby, A. B. Kier, S. Pawlowski, R. J. Diebold, M. Yin, and A. C. Sidman. 1992. Targeted disruption of the mouse transforming growth factor beta 1 gene results in multifocal inflammatory disease. Nature 359: 693-699.
29. Sing, A., A. Roggenkamp, A. Geiger, M., and J. Heesemann. 2002. Yersinia enterocolitica evasion of the host innate immune response by V antigen-induced IL-10 production of macrophages is abrogated in IL-10-deficient mice. J. Immunol. 168:1315-1321.
30. Van-Snick, J. 1989. Interleukin-6: an overview. Annu. Rev. Immunol. 8:253-278.
31. West, A. 1997. Yersiniosis, p. 917-925. In D. Conner, F. Chandler, H. Manz, K. Baird, D. Schwartz, E. Lack, and J. Utz (ed.), Pathology of infectious diseases. Appleton and Lange, Stamford, Conn.