Increased chemical purity using a hydrate

Crystal Growth and Design

Volumn 4, Issue 3, 2004, Pages 539-544

  Black, Simon N ^a   Cuthbert, Murray W ^a   Roberts, Ron J ^a   Stensland, Birgitta ^b  

^a ASTRAZENECA   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PIPERIDINE;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; PURIFICATION;

EID: 2542519098     PISSN: 15287483     EISSN: None     Source Type: Journal    
DOI: 10.1021/cg034222v     Document Type: Article

References (10)

1. Davey, R. J.; Garside, J. From Molecules to Crystallisers: An Introduction to Crystallisation, Oxford Chemistry Primers No 86; Oxford University Press: UK, 2000.
2. Dorset, D. L. Macromolecules 1990, 23, 623-633.
3. Davey, R. J.; Black, S. N.; Logan, D.; Maginn, S. J.; Fairbrother, J. E.; Grant, D. J. W. J. Chem Soc. Faraday Trans. 1992, 88, 3461-3466.
4. Byrn, S. R.; Pfeiffer, R. R.; Stowell, J. G. Solid State Chemistry of Drugs, 2nd ed.; SSCI Inc.: West Lafayette, IN, 1999.
5. Chemburkar, S. J.; Bauer, J.; Deming, K.; Spiwek, H.; Patel, K.; Morris, J.; Henry, R.; Spanton, S.; Dziki, W. P.; Quick, J.; Bauer, P.; Donaubauer, J.; Narayanan, B.A.; Soldani, M.; Riley, D.; McFarland, K. Org. Proc. Res. Dev. 2000, 4, 413-417.
6. Bernstein, J. Polymorphism in Molecular Crystals; Oxford Clarendon Press: New York, 2002.
7. Davey, R. J.; Blagden, N.; Potts, G. D.; Docherty, R. J. Am Chem. Soc. 1997, 119, 1767-1772.
8. Weissbuch, I.; Leiserowitz, L.; Lahav, M. Adv. Mater. 1994, 6, 952-956.
9. Levin, D.; Howells, G. E.; Cuthbert, M. W. Patent Application WO 02/096890 A2, 2002.
10. Zhu, H.; Yuen, C.; Grant, D. J. W. Int. J. Pharm. 1996, 135, 151-160.