Simulated influence of osteoporosis and disc degeneration on the load transfer in a lumbar functional spinal unit

Journal of Biomechanics

Volumn 37, Issue 7, 2004, Pages 1061-1069

  Polikeit, Anne ^a   Nolte, Lutz P ^a   Ferguson, Stephen J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Disc degeneration; Finite element analysis; Lumbar spine; Osteoporosis; Strain distribution

Indexed keywords

BONE; COMPUTER SIMULATION; FINITE ELEMENT METHOD; FRACTURE; HEALTH CARE;

BONE QUALITY; LOAD TRANSFER;

BIOMECHANICS;

ARTICLE; CANCELLOUS BONE; COMPRESSION; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; INTERVERTEBRAL DISK DEGENERATION; LUMBAR SPINE; OSTEOPOROSIS; PRIORITY JOURNAL; RIGIDITY; STRESS STRAIN RELATIONSHIP; WEIGHT BEARING;

BONE DENSITY; HUMANS; INTERVERTEBRAL DISK; LUMBAR VERTEBRAE; MODELS, BIOLOGICAL; OSTEOPOROSIS; WEIGHT-BEARING;

EID: 2542504431     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2003.11.018     Document Type: Article

References (38)

1. Adams M., McNally D., Dolan P. 'stress' distributions inside intervertebral discs. The effects of age and degeneration. Journal of Bone and Joint Surgery, British Volume. 78:1996;965-972
2. Andresen R., Haidekker M.A., Radmer S., Banzer D. CT determination of bone mineral density and structural investigations on the axial skeleton for estimating the osteoporosis-related fracture risk by means of a risk score. British Journal of Radiology. 72:1999;569-578
3. Andresen R., Werner H.J., Schober H.C. Contribution of the cortical shell of vertebrae to mechanical behaviour of the lumbar vertebrae with implications for predicting fracture risk. British Journal of Radiology. 71:1998;759-765
4. Antonacci M.D., Hanson D.S., Leblanc A., Heggeness M.H. Regional variation in vertebral bone density and trabecular architecture are influenced by osteoarthritic change and osteoporosis. Spine. 22:1997;2393-2401
5. Augat P., Link T., Lang T.F., Lin J.C., Majumdar S., Genant H.K. Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations. Medical Engineering & Physics. 20:1998;124-131
6. Borah B., Gross G.J., Dufresne T.E., Smith T.S., Cockman M.D., Chmielewski P.A., Lundy M.W., Hartke J.R., Sod E.W. Three-dimensional microimaging (MRmicroI and microCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis. The Anatomical Record. 265:2001;101-110
7. Brown M.D., Holmes D.C., Heiner A.D. Measurement of cadaver lumbar spine motion segment stiffness. Spine. 27:2002;918-922
8. Brown M.D., Holmes D.C., Heiner A.D., Wehman K.F. Intraoperative measurement of lumbar spine motion segment stiffness. Spine. 27:2002;954-958
9. Buckwalter J.A. Aging and degeneration of the human intervertebral disc. Spine. 20:1995;1307-1314
10. Dai L. The relationship between vertebral body deformity and disc degeneration in lumbar spine of the senile. European Spine Journal. 7:1998;40-44
11. Dougherty G. The peak CT number of profiles perpendicular to the vertebral cortical shell may be a useful indicator of the integrity of the cortical shell. Medical Engineering & Physics. 22:2000;487-491
12. Frei H., Oxland T.R., Rathonyi G.C., Nolte L.P. The effect of nucleotomy on lumbar spine mechanics in compression and shear loading. Spine. 26:2001;2080-2089
13. Harada A., Okuizumi H., Miyagi N., Genda E. Correlation between bone mineral density and intervertebral disc degeneration. Spine. 23:1998;857-862
14. Homminga J., Weinans H., Gowin W., Felsenberg D., Huiskes R. Osteoporosis changes the amount of vertebral trabecular bone at risk of fracture but not the vertebral load distribution. Spine. 26:2001;1555-1561
15. Iatridis J., Kumar S., Foster R., Weidenbaum M., Mow V.C. Shear mechanical properties of human lumbar annulus fibrosus. Journal of Orthopaedic Research. 17:1999;732-737
16. Kanis J., Melton L., Christiansen C., Johnston C., Khaltaev N. The diagnosis of osteoporosis. Journal of Bone and Mineral Research. 9:1994;1137-1141
17. Keller T.S., Holm S., Hansson T., Spengler D.M. The dependence of intervertebral disc mechanical properties on physiologic conditions. 1990 Volvo Award in experimental studies. Spine. 15:1990;751-761
18. Lang T., Augat P., Majumdar S., Ouyang X., Genant H.K. Noninvasive assessment of bone density and structure using computed tomography and magnetic resonance. Bone. 22:1998;149S-153S
19. Marchand F., Ahmed A. Investigation of the laminate structure of lumbar disc anulus fibrosus. Spine. 15:1990;402-410
20. Margulies J., Payzer A., Nyska M., Neuwirth M., Floman Y., Robin G. The relationship between degenerative changes and osteoporosis in the lumbar spine. Clinical Orthopaedics. 324:1996;145-152
21. Millard J., Augat P., Link T., Kothari M., Newitt D., Genant H., Majumdar S. Power spectral analysis of vertebral trabecular bone structure from radiographs. orientation dependence and correlation with bone mineral density and mechanical properties Calcified Tissue International. 63:1998;482-489
22. Mosekilde L. Vertebral structure and strength in vivo and in vitro. Calcified Tissue International. 53:1993;S121-S125. (S126 discussion)
23. Muller R., Ruegsegger P. Analysis of mechanical properties of cancellous bone under conditions of simulated bone atrophy. Journal of Biomechanics. 29:1996;1053-1060
24. Nicholson P.H., Cheng X.G., Lowet G., Boonen S., Davie M.W., Dequeker J., Van der Perre G. Structural and material mechanical properties of human vertebral cancellous bone. Medical Engineering & Physics. 19:1997;729-737
25. Oxland T., Lund T., Jost B., Cripton P., Lippuner K., Jaeger P., Nolte L.-P. The relative importance of vertebral bone density and disc degeneration in spinal flexibility and interbody implant performance. Spine. 21:1996;2558-2569
26. Polikeit, A., 2002. Finite element analysis of the lumbar spine: clinical applications. Ph.D. thesis, University of Bern, Bern.
27. Polikeit A., Ferguson S., Nolte L., Orr T. Factors influencing stresses in the lumbar spine after the insertion of intervertebral cages. finite element analysis European Spine Journal. 12:2003;413-420
28. Polikeit A., Nolte L., Ferguson S. The effect of cement augmentation on the load transfer in an osteoporotic functional spinal unit, finite element analysis. Spine. 28:2003;991-996
29. Rice J., Cowin S., Bowman J. On the dependence of the elasticity and strength of cancellous bone on apparent density. Journal of Biomechanics. 21:1988;155-168
30. Ritzel H., Amling M., Hahn M., Maas R., Delling G. Quantitative morphology of vertebral body cortical bone. Building block for noninvasive calculation of fracture threshold in osteoporosis. Radiologe. 38:1998;315-320
31. Ritzel H., Amling M., Posl M., Hahn M., Delling G. The thickness of human vertebral cortical bone and its changes in aging and osteoporosis. a histomorphometric analysis of the complete spinal column from thirty-seven autopsy specimens Journal of Bone and Mineral Research. 12:1997;89-95
32. Schaffler M., Burr D. Stiffness of compact bone. effects of porosity and density Journal of Biomechanics. 21:1988;13-16
33. Shirado O., Kaneda K., Tadano S., Ishikawa H., McAfee P.C., Warden K.E. Influence of disc degeneration on mechanism of thoracolumbar burst fractures. Spine. 17:1992;286-292
34. Shirazi-Adl S.A., Shrivastava S.C., Ahmed A.M. Stress analysis of the lumbar disc-body unit in compression. A three-dimensional nonlinear finite element study. Spine. 9:1984;120-134
35. Steffen T., Tsantrizos A., Aebi M. Effect of implant design and endplate preparation on the compressive strength of interbody fusion constructs. Spine. 25:2000;1077-1084
36. Tsurusaki K., Ito M., Hayashi K. Differential effects of menopause and metabolic disease on trabecular and cortical bone assessed by peripheral quantitative computed tomography (pQCT). British Journal of Radiology. 73:2000;14-22
37. Twomey L., Taylor J., Furniss B. Age changes in the bone density and structure of the lumbar vertebral column. Journal of Anatomy. 136(Part 1):1983;15-25
38. Van Rietbergen, B., Eckstein, F., Koller, B., Huiskes, R., Baaijens, F., Ruegsegger, P., 2000. Trabecular bone tissue strains in the healthy and osteoporotic human femur. In: Proceedings of the 46th Annual Meeting of the Orthopaedic Research Society, Orlando, FL, USA.