Pediatric myocardial protection: A cardioplegic strategy is the "Solution"

Pediatric Cardiac Surgery Annual

Volumn 7, Issue 1, 2004, Pages 141-154

  Allen, Bradley S ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cardioplegia; Pediatric myocardial protection

Indexed keywords

ASPARTIC ACID; CALCIUM; CITRIC ACID; GLUCOSE; GLUTAMIC ACID; MAGNESIUM; MAGNESIUM SULFATE; MANNITOL; PHOSPHATE; POTASSIUM CHLORIDE; TROMETAMOL;

ARTICLE; BLOOD; CARDIOPLEGIA; CLINICAL PRACTICE; CRYSTALLOID; CYANOSIS; DOSE RESPONSE; HEART ARREST; HEART DEVELOPMENT; HEART HYPERTROPHY; HEART INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE OVERLOAD; HEART VENTRICLE PRESSURE; HIGH RISK PATIENT; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; INTRAOPERATIVE PERIOD; MORBIDITY; PEDIATRIC SURGERY; PERFUSION PRESSURE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; RISK FACTOR; SAFETY; SURGICAL APPROACH; SURGICAL MORTALITY; TREATMENT OUTCOME; TREATMENT PLANNING; WARMING;

EID: 2542503677     PISSN: 10929126     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.pcsu.2004.02.001     Document Type: Article

References (61)

1. Buckberg GD, Allen BS: Myocardial protection management during adult cardiac operations, in Baue AE, Geha AS, Hammond GL, et al (eds): Glenn's Thorac and Cardiovasc Surgery. East Norwalk, CT, Appleton and Lange, 1995, pp 1653-1687
2. Castaneda AR, Jonas RA, Mayer JE Jr, et al: Myocardial preservation in the immature heart, in Castaneda AR, Jonas RA, Mayer JE Jr, et al (eds): Cardiac Surgery of the Neonate and Infant. Philadelphia, PA, Saunders, 1994, pp 41-54
3. Hammon JW Jr: Myocardial protection in the immature heart. Ann Thorac Surg 60:839-842, 1995
4. Romero TE, Friedman WF: Limited left vcntricular response to volume overload in the neonatal period. Pediatr Res 13:910-915, 1979
5. Barth MJ, Ilbawi MN, Allen BS: Pediatric myocardial protection: An overview. Semin Thorac Cardiovasc Surg 13:56-72, 2001
6. Julia P, Kofsy ER, Buckberg GD, et al: Studies of myocardial protection in the immature heart. I. Enhanced tolerance of immature versus adult myocardium to global ischemia with reference to metabolic differences. J Thorac Cardiovasc Surg 100:879-887, 1990
7. Del Nido PJ, Mickle DAG, Wilson GJ, et al: Inadequate myocardial protection with cold cardioplegic arrest during repair of Tetralogy of Fallot. J Thorac Cardiovasc Surg 95:223-229, 1988
8. Silverman N, Kohler J, Levitsky S, et al: Chronic hypoxemia depresses global ventricular function and predisposes to depletion of high energy phosphates during cardioplegic arrest. Ann Thorac Surg 37:304-308, 1984
9. Wittnich C, Maitland A, Vincente W, et al: Not all neonatal hearts are equally protected from ischemic damage during hypothermia. Ann Thorac Surg 52:1000-1004, 1991
10. Friedman WF: The intrinsic physiologic properties of the developing heart. Prog Cardiovasc Dis 15:87-111, 1972
11. Sink JD, Pellom GL, Currie WD, et al: Response of hypertrophied myocardium to ischemia. J Thorac Cardiovasc Surg 81:865-872, 1981
12. Peyton RB, Jones RB, Attarian D, et al: Depressed high-energy phosphate content in hypertrophied ventricles of animal and man. Ann Thorac Surg 196:278-284, 1982
13. Graham TP Jr, Erath HG Jr, Buckspan GS, et al: Myocardial anaerobic metabolism during isoprenaline infusion in a cyanotic animal model: possible cause of myocardial dysfunction in cyanotic congenital heart disease. Cardiovas Res 13:401-406, 1979
14. Fujiwara T, Kurtts T, Anderson W, et al: Myocardial protection in cyanotic neonatal limbs. J Thorac Cardiovasc Surg 96:700-710, 1988
15. Bolling KS, Allen BS, Raham SK, et al: Prevention of the hypoxic/reoxygenation injury using a leukocyte depleting filter. J Thorac Cardiovasc Surg 113:1081-1090, 1997
16. Bolling KS, Allen BS, Ramon S, et al: Myocardial protection in normal and hypoxically stressed neonatal hearts: The superiority of hypocalcemic versus normocalcemic blood cardioplegia. J Thorac Cardiovasc Surg 112:1193-1201, 1996
17. Bolling KS, Allen BS, Wang T, et al: Myocardial protection in normal and hypoxically stressed neonatal hearts: The superiority of blood versus crystalloid cardioplegia. J Thorac Cardiovasc Surg 113:994-1005, 1997
18. Allen BS, Ilbawai MN: Hypoxia, reoxygenation and the role of systemic leukodepletion in pediatric heart surgery. Perfusion 16:19-29, 2001
19. Teoh KH, Mickle DAG, Weisel RD, et al: Effect of oxygen tension and cardiovascular operations on the myocardial antioxidant enzyme activities in patients with tetralogy of Fallot and aorta-coronary bypass. J Thorac Cardiovasc Surg 104:159-164, 1992
20. Del Nido PJ, Mickle DAG, Wilson G, et al: Evidence of myocardial free radical injury during elective repair of tetralogy of Fallot. Circulation 76:174-179, 1987
21. Allen BS: Hypoxia, reoxygenation and the role of leukodepletion in the intraoperative management of congenital heart disease, in Mathesis G, Mortiz A, Sholz M (eds): Leukocyte Depletion in Cardiac Surgery and Cardiology. Basel, Switzerland, Karger, 2002, pp 111-134
22. Toyoda Y, Yamaguchi M, Yoshimura N, et al: Cardioprotective effects and the mechanisms of terminal warm blood cardioplegia in pediatric cardiac surgery. J Thorac Cardiovasc Surg 125:1242-1251, 2003
23. Corno AF, Bethancourt DM, Laks H, et al: Myocardial protection in the neonatal heart: A comparison of topical hypothermia and crystalloid and blood cardioplegic solutions. J Thorac Cardiovasc Surg 93:163-172, 1987
24. Fujiwara T, Heinle J, Britton L, et al: Myocardial preservation in neonatal and blood cardioplegia. J Thorac Cardiovasc Surg 101:703-712, 1991
25. Buckberg GD, Coghlan HC, Hoffman JIE, et al: The structure and function of the helical heart and its buttress wrapping. VII. Critical importance of the septum for right ventricular function. Semin Thorac Cardiovasc Surg 13:402-416, 2001
26. Kronon M, Allen BS, Bolling KS, et al: The role of cardioplegic induction temperature and amino acid enrichment in neonatal myocardial protection. Ann Thorac Surg 3:756-764, 2000
27. Hearse DJ, Stewart DA, Braimbridge MV: Myocardial protection during ischemic cardiac arrest-The importance of magnesium in cardioplegic infusates. J Thorac Cardiovasc Surg 75:877-885, 1978
28. Aoki M, Nomura F, Kawata H, et al: Effect of calcium and preischemic hypothermia on recovery of myocardial function after cardioplegic ischemia in neonatal lambs. J Thorac Cardiovasc Surg 105:207-213, 1993
29. Kronon M, Allen BS, Raham SK, et al: The relationship between calcium and magnesium in pediatric myocardial protection. J Thorac Cardiovasc Surg 114:1010-1019, 1997
30. Boland R, Martonosi A, Tillack TW: Developmental changes in the composition and function of sarcoplasmic reticulum. J Biol Chem 249:612-623, 1974
31. Lareau S, Boyle AJ, Stewart LC, et al: The role of magnesium in myocardial preservation. Magnes Res 8:85-97, 1995
32. Sha Kerinia T, Ali IM, Sullivan JA: Magnesium in cardioplegia: Is it necessary? Can J Surg 39:397-400, 1996
33. Bouceck RJ Jr, Kasselberg AG, Boerth RC, et al: Myocardial injury in infants with congenital heart disease: Evaluation by creatine kinase MB isoenzyme analysis. Am J Cardiol 50:129-135, 1982
34. Kronon M, Allen BS, Hernan J, et al: Superiority of magnesium cardioplegia in neonatal myocardial protection. Ann Thorac Surg 68:2285-2295, 1999
35. Hearse D, Humphrey S, Bullock G: The oxygen paradox and the calcium paradox: two facets of the same problem? J Mol Cell Cardiol 10:641-668, 1978
36. Tsukube T, McCully JD, Federman M, et al: Developmental differences in cytosolic calcium accumulation associated with surgically induced global ischemia: Optimization of cardioplegic protection and mechanism of action. J Thorac Cardiovasc Surg 112:175-184, 1996
37. Allen BS, Rosenkranz ER, Buckberg GD: Studies of prolonged regional ischemia. VI: Myocardial infraction with left ventricular power failure: a medical/surgical emergency requiring urgent revascularization with maximal protection of remote muscle. J Thorac Cardiovasc Surg 98:691-703, 1989
38. Kirklin J, Barrat-Boyes B: Myocardial management during cardiac surgery with cardiopulmonary bypass, in Kirklin J, Barrat-Boyes B (eds): Cardiac Surgery. New York, NY, Churchill Livingstone, 1993, pp 129-166
39. Ihnken K, Morita K, Buckberg GD, et al: Studies of hypoxemic/reoxygenation injury: Without aortic clamping III. Comparison of the magnitude and damage by hypoxemia/reoxygenation versus ischemia/reperfusion. J Thorac Cardiovasc Surg 110:1182-1189, 1995
40. Boyle EM Jr, Pohlman TH, Cornejo CJ, et al: Ischemia-reperfusion injury. Ann Thorac Surg 64:S24-S30, 1997
41. Follette D, Fey K, buckberg GD, et al: Reducing post-ischemic damage by temporary modifications of reperfusate calcium, potassium, pH, and osmolarity. J Thorac Cardiovasc Surg 82:221-238, 1981
42. Allen BS, Okamoto F, Buckberg GD, et al: Studies of controlled reperfusion after ischemia XV: Immediate functional recovery after 6 hours of regional ischemia by careful control of conditions of reperfusion and composition of reperfusate. J Thorac Cardiovasc Surg 92:621-635, 1986
43. Teoh KH, Christakis GT, Weisel RD, et al: Accelerated myocardial metabolic recovery with terminal warm blood cardioplegia. J Thorac Cardiovasc Surg 91:888-895, 1986
44. Kronon M, Allen BS, Halldorsson A, et al: L-arginine, prostaglandin, and white cell filtration equally improve myocardial protection in stressed neonatal hearts. J Thorac Cardiovasc Surg 118:665-673, 1999
45. Kronon M, Allen BS, Raham SK, et al: Reducing post-ischemic reperfusion damage in neonates using a terminal warm substrate enriched blood cardioplegic reperfusate. Ann Thorac Surg 70:765-770, 2000
46. Taggart DP, Hadjinikolas L, Hooper J, et al: Effects of age and ischemic times on biochemical evidence of myocardial injury after pediatric cardiac operations. J Thorac Cardiovasc Surg 113:728-735, 1997
47. Chaturvedi R, Lincoln C, Gothard J, et al: Left ventricular dysfunction after open repair of simple congenital heart defects in infants and children: Quantitation with the use of a conductance catheter immediately after bypass. J Thorac Cardiovasc Surg 115:77-83, 1998
48. Allen BS, Winkelmann JW, Hanafy HM, et al: Retrograde cardioplegia does not perfuse the right ventricle. J Thorac Cardiovasc Surg 109:1116-1126, 1995
49. Allen BS, Evans-Murcia D, Hartz RS: Integrated cardioplegia allows complex valve repairs in all patients. Ann Thorac Surg 62:23-30, 1996
50. Partington MT, Acar C, Buckberg GD, et al: Studies of retrograde cardioplegia II: Nutritive blood flow distribution in normal and jeopardized myocardium. J Thorac Surg 97:613-622, 1989
51. Gates RN, Laks H, Drinkwater DC, et al: The microvascular distribution of cardioplegic solution in the piglet heart-retrograde vs. antegrade delivery. J Thorac Cardiovasc Surg 105:845-853, 1993
52. Buckberg GD, Beyersdorf F, Kato NS: Technical considerations and logic of antegrade and retrograde blood cardioplegic delivery. Semin Thorac Cardiovasc Surg 5:125-133, 1993
53. Buckberg GD, Allen BS, Beyersdorf F: Ischemia-reperfusion in cardiac surgery, in Piper HM, Preusse CJ (eds): Blood Cardioplegic Strategics During Adult Cardiac Operaations. Kluwer Academic, 1993, pp 181-227
54. Buckberg GD, Beyersdorf F, Allen BS, et al: Integrated myocardial management: Background and initial application. J Cardiac Surg 10:68-89, 1995
55. Kronon M, Bolling KS, Allen BS, et al: The importance of monitoring cardioplegia infusion pressure in neonatal myocardial protection. Ann Thorac Surg 66:1358-1364, 1998
56. Kronon MT, Allen BS, Halldorsson A, et al: Delivery of a nonpotassium modified maintenance solution to enhance myocardial protection in stressed neonatal hearts: A new approach. J Thorac Cardiovasc Surg 23:119-129, 2001
57. Rebeyka I, Hanan SA, Borges MR, et al: Rapid cooling contracture of the myocardium. J Thorac Cardiovasc Surg 100:240-249, 1990
58. Landymore RW, Marvle AE, Mac Aulay MA, et al: Oxygenated cardioplegia ameliorates the adverse effects of small amplitude electrical recording of activity on myocardial, metabolic and functional recovery. Eur J Cardiothorac Surg 5:37-40, 1991
59. Mizuno BR, Buckberg GD, Young HH: Hypocalcemia in piglets reduces cardiac and pulmonary vascular disturbance after hypoxemia and reoxygenation during cardiopulmonary bypass. J Thorac Cardiovasc Surg 47:302-310, 1999
60. Sharikabad MN, Ostbye KM, Brors O: Increased [Mg 2+] 0 reduces influx and disruption of mitochondrial membrane potential during reoxygenation. Am J Physiol Heart Circ Physiol 281:H2113-H2123, 2001
61. Caspi J, Rudis E, Bar I, et al: Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg 59:942-947, 1995