In vivo role of heme oxygenase in ischemic coronary vasodilation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 6 55-6, 2004, Pages

  Nishikawa, Yasuhiro ^a   Stepp, David W ^b   Merkus, Daphne ^a   Jones, Deron ^a   Chilian, William M ^c  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon monoxide; Hypoperfusion; Ischemia; Microcirculation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; BILIVERDIN; CARBON MONOXIDE; CYCLIC GMP; CYTOCHROME P450; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; HEME ARGINATE; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; HEMOPROTEIN; INDOMETACIN; MESOPORPHYRIN TIN; MYOGLOBIN; N(G) METHYLARGININE; NITRIC OXIDE; POTASSIUM CHLORIDE; PROSTAGLANDIN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DOG; ENZYME ACTIVATION; FLUORESCENCE ANGIOGRAPHY; HEART MUSCLE ISCHEMIA; MICROANGIOGRAPHY; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROBOSCOPIC FLUORESCENCE MICROANGIOGRAPHY; STROBOSCOPY; VASODILATATION;

ANIMALS; CARBON MONOXIDE; CORONARY CIRCULATION; CYCLIC GMP; CYCLOOXYGENASE INHIBITORS; DOGS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HEME OXYGENASE (DECYCLIZING); INDOMETHACIN; MICROCIRCULATION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; OMEGA-N-METHYLARGININE; POTASSIUM CHANNELS; POTASSIUM CHLORIDE; VASODILATION;

EID: 2542497841     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00671.2003     Document Type: Article

References (49)

1. Abraham NG, Pinto A, Levere RD, and Mullane K. Identification of heme oxygenase and cytochrome P-450 in the rabbit heart. J Mol Cell Cardiol 19: 73-81, 1987.
2. Appleton SD, Marks GS, Nakatsu K, Brien JF, Smith GN, and Graham CH. Heme oxygenase activity in placenta: direct dependence on oxygen availability. Am J Physiol Heart Circ Physiol 282: H2055-H2059, 2002.
3. Bassenge E. Endothelium-mediated regulation of coronary tone. Basic Res Cardiol 86: 69-76, 1991.
4. Bolli R, Triana F, and Jeroudi MO. Postischemic mechanical and vascular dysfunction (myocardial "stunning" and microvascular "stunning") and the effects of calcium-channel blockers on ischemia/reperfusion injury. Clin Cardiol 12: III16-III25, 1989.
5. Bolli R, Triana JF, and Jeroudi MO. Prolonged impairment of coronary vasodilation after reversible ischemia. Evidence for microvascular "stunning." Circ Res 67: 332-343, 1990.
6. Caudill TK, Resta TC, Kanagy NL, and Walker BR. Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. Am J Physiol Regul Integr Comp Physiol 275: R1025-R1030, 1998.
7. Chan EC and Woodman OL. Enhanced role for the opening of potassium channels in relaxant responses to acetylcholine after myocardial ischemia and reperfusion in dog coronary arteries. Br J Pharmacol 126: 925-932, 1999.
8. Chilian WM and Layne SM. Coronary microvascular responses to reductions in perfusion pressure. Evidence for persistent arteriolar vasomotor tone during coronary hypoperfusion. Circ Res 66: 1227-1238, 1990.
9. Christova T, Diankova Z, and Setchenska M. Heme oxygenase-carbon monoxide signaling pathway as a physiological regulator of vascular smooth muscle cells. Acta Physiol Pharmacol Bulg 25: 9-17, 2000.
10. Clark JE, Foresti R, Sarathchandra P, Kaur H, Green CJ, and Motterlini R. Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction. Am J Physiol Heart Circ Physiol 278: H643-H651, 2000.
11. Dart C and Standen NB. Adenosine-activated potassium current in smooth muscle cells isolated from the pig coronary artery. J Physiol 471: 767-786, 1993.
12. Daut J, Maier-Rudolph W, von Beckerath N, Mehrke G, Gunther K, and Goedel-Meinen L. Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science 247: 1341-1344, 1990.
13. Durante W and Schafer AI. Carbon monoxide and vascular cell function (Review). Int J Mol Med 2: 255-262, 1998.
14. Epstein SE, Cannon RO 3rd, and Talbot TL. Hemodynamic principles in the control of coronary blood flow. Am J Cardiol 56: 4E-10E, 1985.
15. Feigl EO. Coronary physiology. Physiol Rev 63: 1-205, 1983.
16. Fernandez M, Lambrecht RW, and Bonkovsky HL. Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity. J Hepatol 34: 812-817, 2001.
17. Foresti R, Goatly H, Green CJ, and Motterlini R. Role of heme oxygenase-1 in hypoxia-reoxygenation: requirement of substrate heme to promote cardioprotection. Am J Physiol Heart Circ Physiol 281: H1976-H1984, 2001.
18. Gagou H, Kadinov B, Hristou K, Boeu K, Dimiter I, Boltan T, and Duridanova D. Role of constitutively expressed heme oxygenase-2 in the regulation of guinea pig coronary artery tone. Pflügers Arch 446: 412-421, 2003.
19. Gallagher KP. Transmural steal with isoproterenol and exercise in post-stenotic myocardium. Basic Res Cardiol 85, Suppl 1: 145-155, 1990.
20. Gryglewski RJ, Chlopicki S, and Niezabitowski P. Endothelial control of coronary flow in perfused guinea pig heart. Basic Res Cardiol 90: 119-124, 1995.
21. Hintze TH and Kaley G. Prostaglandins and the control of blood flow in the canine myocardium. Circ Res 40: 313-320, 1977.
22. Johnson FK, Teran FJ, Prieto-Carrasquero M, and Johnson RA. Vascular effects of a heme oxygenase inhibitor are enhanced in the absence of nitric oxide. Am J Hypertens 15: 1074-1080, 2002.
23. Johnson RA, Kozma F, and Colombari E. Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions. Braz J Med Biol Res 32: 1-14, 1999.
24. Johnson RA, Lavesa M, DeSeyn K, Scholer MJ, and Nasjletti A. Heme oxygenase substrates acutely lower blood pressure in hypertensive rats. Am J Physiol Heart Circ Physiol 271: H1132-H1138, 1996.
25. Kappas A, Drummond GS, and Valaes T. A single dose of Sn-mesoporphyrin prevents development of severe hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns. Pediatrics 108: 25-30, 2001.
26. Kim YD, Fomsgaard JS, Heim KF, Ramwell PW, Thomas G, Kagan E, Moore SP, Coughlin SS, Kuwahara M, and Analouei A. Brief ischemia-reperfusion induces stunning of endothelium in canine coronary artery. Circulation 85: 1473-1482, 1992.
27. Komaru T, Lamping KG, Eastham CL, and Dellsperger KC. Role of ATP-sensitive potassium channels in coronary microvascular autoregulatory responses. Circ Res 69: 1146-1151, 1991.
28. Kostic MM and Schrader J. Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res 70: 208-212, 1992.
29. Kozma F, Johnson RA, and Nasjletti A. Role of carbon monoxide in heme-induced vasodilation. Eur J Pharmacol 323: R1-R2, 1997.
30. Kozma F, Johnson RA, Zhang F, Yu C, Tong X, and Nasjletti A. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am J Physiol Regul Integr Comp Physiol 276: R1087-R1094, 1999.
31. Leffler CW, Nasjletti Yu C A, Johnson RA, Fedinec AL, and Walker N. Carbon monoxide and cerebral microvascular tone in newborn pigs. Am J Physiol Heart Circ Physiol 276: H1641-H1646, 1999.
32. Maseri A. Coronary blood flow, and myocardial perfusion in humans: mechanisms of acute transient myocardial ischemia. J Cardiovasc Pharmacol 8: S17-S20, 1986.
33. Maulik N, Engelman DT, Watanabe M, Engelman RM, Rousou JA, Flack JE 3rd, Deaton DW, Gorbunov NV, Elsayed NM, Kagan VE, and Das DK. Nitric oxide/carbon monoxide. A molecular switch for myocardial preservation during ischemia. Circulation 94: 11398-11406, 1996.
34. Morita T, Perrella MA, Lee ME, and Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92: 1475-1479, 1995.
35. Motterlini R, Foresti R, Bassi R, Calabrese V, Clark JE, and Green CJ. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J Biol Chem 275: 13613-13620, 2000.
36. Nakayama M, Takahashi K, Kitamuro T, Yasumoto K, Katayose D, Shirato K, Fujii-Kuriyama Y, and Shibahara S. Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells. Biochem Biophys Res Commun 271: 665-671, 2000.
37. + channel blocker, inhibits coronary autoregulation in anesthetized dogs. Circ Res 73: 771-776, 1993.
38. Nellis SH and Whitesell L. Phasic pressures and diameters in small epicardial veins of the unrestrained heart. Am J Physiol Heart Circ Physiol 257: H1056-H1061, 1989.
39. Nishikawa Y, Stepp DW, and Chilian WM. In vivo location and mechanism of EDHF-mediated vasodilation in canine coronary microcirculation. Am J Physiol Heart Circ Physiol 277: H1252-H1259, 1999.
40. Nishikawa Y, Stepp DW, and Chilian WM. Nitric oxide exerts feedback inhibition on EDHF-induced coronary arteriolar dilation in vivo. Am J Physiol Heart Circ Physiol 279: H459-H465, 2000.
41. Node KM, Kitakaze M, Kosaka H, Komamura K, Minamino T, Tada M, Inoue M, Hori M, and Kamada T. Plasma nitric oxide end products are increased in the ischemic canine heart. Biochem Biophys Res Commun 211: 370-374, 1995.
42. + channels in the protective effect of ACE inhibition against ischemic myocardial injury. Hypertension 31: 1290-1298, 1998.
43. Smith TP Jr and Canty JM Jr. Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flow-dependent resistance adjustments in conscious dogs. Circ Res 73: 232-240, 1993.
44. Stepp DW, Nishikawa Y, and Chilian WM. Regulation of shear stress in the canine coronary microcirculation. Circulation 100: 1555-1561, 1999.
45. Turner CP, Bergeron M, Matz P, Zegna A, Noble LJ, Panter SS, and Sharp FR. Heme oxygenase-1 is induced in glia throughout brain by subarachnoid hemoglobin. J Cereb Blood Flow Metab 18: 257-273, 1998.
46. Vreman HJ, Ekstrand BC, and Stevenson DK. Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photo reactivity. Pediatr Res 33: 195-200, 1993.
47. ca channels in vascular smooth muscle cells. Pflügers Arch 434: 285-291, 1997.
48. Yet SF, Pellacani A, Patterson C, Tan L, Folta SC, Foster L, Lee WS, Hsieh CM, and Perrella MA. Induction of heme oxygenase-1 expression in vascular smooth muscle cells. A link to endotoxic shock. J Biol Chem 272: 4295-4301, 1997.
49. Zhang F, Kaide J, Wei Y, Jiang H, Yu C, Balazy M, Abraham NG, Wang W, and Nasjletti A. Carbon monoxide produced by isolated arterioles attenuates pressure-induced vasoconstriction. Am J Physiol Heart Circ Physiol 281: H350-H358, 2001.