Experimental models to study the physiology, pathophysiology, and pharmacology of the lower urinary tract

Journal of Pharmacological and Toxicological Methods

Volumn 49, Issue 3, 2004, Pages 201-210

  Fry, C H ^a  

^a Institute of Urology   (United Kingdom)

Author keywords

Bladder denervation; Bladder obstruction; Cultured cells; Electromyography; Electrophysiology; Intracellular ions; Isolated cells; Isometric tension; Multicellular preparations

Indexed keywords

ACETYLCHOLINE; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; TETRODOTOXIN;

ARTICLE; BLADDER DYSFUNCTION; BLADDER FUNCTION; BLADDER OBSTRUCTION; CELL CULTURE; CELL ISOLATION; CELL TYPE; CONCENTRATION (PARAMETERS); ELECTROMYOGRAPHY; ELECTROPHYSIOLOGY; EXPERIMENTAL MODEL; FUNCTIONAL DISEASE; HUMAN; IMPLANT; MUSCLE CONTRACTILITY; NONHUMAN; OVERACTIVE BLADDER; SMOOTH MUSCLE FIBER; TENSION; URETHRA;

ANIMALS; CELLS, CULTURED; ELECTROMYOGRAPHY; ELECTROPHYSIOLOGY; HUMANS; ISOMETRIC CONTRACTION; MODELS, THEORETICAL; MUSCLE CONTRACTION; MUSCLE, SMOOTH; URINARY BLADDER; URINARY BLADDER DISEASES; URINARY TRACT; UROTHELIUM;

EID: 2542474062     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2004.03.002     Document Type: Article

References (54)

1. Atala A. Experimental and clinical experience with tissue engineering techniques for urethral reconstruction. Urology Clinics of North America. 29:2002;485-492
2. Athwal B., Berkley K.J., Hussain I., Brennan A., Craggs M., Sakakibara R., Frackowiak R.S., Fowler C.J. Brain responses to changes in bladder volume and urge to void in healthy men. Brain. 124:2001;369-377
3. Azadzoi K.M., Tarcan T., Kozlowski R., Krane R.J., Siroky M.B. Overactivity and structural changes in the chronically ischemic bladder. Journal of Urology. 162:1999;1768-1778
4. Azadzoi K.M., Tarcan T., Siroky M.B., Krane R.J. Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit. Journal of Urology. 161:1999;1626-1635
5. Ballaro A., Mundy A.R., Fry C.H., Craggs M.D. Electromyographic detection of purinergic activity in guinea pig detrusor smooth muscle. Journal of Urology. 169:2003;377-381
6. Ballaro A., Mundy A.R., Fry C.H., Craggs M.D. Bladder electrical activity: The elusive electromyogram. British Journal of Urology International. 92:2003;78-84
7. Bayliss M., Wu C., Newgreen D., Mundy A.R., Fry C.H. A quantitative study of atropine-resistant contractions in human detrusor smooth muscle, from stable, unstable and obstructed bladders. Journal of Urology. 162:1999;1833-1839
8. Braverman A.S., Luthin G.R., Ruggieri M.R. M2 muscarinic receptor contributes to contraction of the denervated rat urinary bladder. American Journal of Physiology. 275:1998;R1654-R1660
9. Buttyan R., Chen M.W., Levin R.M. Animal models of bladder outlet obstruction and molecular insights into the basis for the development of bladder dysfunction. European Urology. 32(S1):1997;32-39
10. 2+ signalling in cultured smooth muscle cells from human bladder. Experimental Physiology. 8:1996;553-564
11. Chuang Y.C., Fraser M.O., Yu Y., Chancellor M.B., de Groat W.C., Yoshimura N. The role of bladder afferent pathways in bladder hyperactivity induced by the intravesical administration of nerve growth factor. Journal of Urology. 165:2001;975-979
12. Craggs M.C. The elusive electromyogram: Fact vs artefact. Neurourology and Urodynamics. 17:1998;80-81
13. Cross W.R., Thomas D.F., Southgate J. Tissue engineering and stem cell research in urology. British Journal of Urology International. 92:2003;165-171
14. Damaser M.S., Arner A., Uvelius B. Partial outlet obstruction induces chronic distension and increased stiffness of rat urinary bladder. Neurourology and Urodynamics. 15:1996;650-665
15. de Filippo R.E., Yoo J.J., Atala A. Urethral replacement using cell seeded tubularized collagen matrices. Journal of Urology. 168:2002;1789-1792
16. de Groat W.C. Plasticity of bladder reflex pathways during postnatal development. Physiology & Behavior. 77:2002;689-692
17. de Groat W.C., Kawatani M. Reorganization of sympathetic preganglionic connections in cat bladder ganglia following parasympathetic denervation. Journal of Physiology. 409:1989;431-449
18. de Groat W.C., Yoshimura N. Pharmacology of the lower urinary tract. Annual Review of Pharmacology and Toxicology. 41:2001;691-721
19. Drake M.J., Harvey I.J., Gillespie J.I. Autonomous activity in the isolated guinea pig bladder. Experimental Physiology. 88:2003;19-30
20. Ekstrom J., Uvelius B. Length-tension relations of smooth muscle from normal and denervated rat urinary bladders. Acta Physiologica Scandinavica. 112:1981;443-447
21. Fry C.H. Detrusor smooth muscle physiology. Mundy A.R. The Scientific Basis of Urology. Oxford. 2004;. Chapter 15
22. Glerum J.J., van Mastrigt R. Mechanical properties of mammalian single smooth muscle cells: Evaluation of a modified technique for attachment of cells to the measurement apparatus. Journal of Muscle Research and Cell Motility. 11:1990;338-343
23. Gobet R., Park J.M., Nguyen H.T., Chang B., Cisek L.J., Peters C.A. Renal renin-angiotensin system dysregulation caused by partial bladder outlet obstruction in fetal sheep. Kidney International. 56:1999;1654-1661
24. Hawthorn M.H., Chapple C.R., Cock M., Chess-Williams R. Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro. British Journal of Pharmacology. 129:2000;416-419
25. Kato K., Wein A.J., Radzinski C., Longhurst P.A. Short term functional effects of bladder outlet obstruction in the cat. Journal of Urology. 143:1990;1020-1025
26. Liston T.G., Palfrey E.L.H., Raimbach S.J., Fry C.H. The effects of pH on human and ferret detrusor muscle function. Journal of Physiology. 432:1991;1-21
27. Nielsen K.K. Blood flow rate and total blood flow related to length density and total length of blood vessels in mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction. Neurourology and Urodynamics. 14:1995;177-186
28. Nielsen K.K., Andersen C.B., Petersen L.K., Oxlund H., Nordling J. Morphological, stereological, and biochemical analysis of the mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction. Neurourology and Urodynamics. 14:1995;269-284
29. Nyirady P., Thiruchelvam N., Fry C.H., Godley M.L., Winyard P.J., Peebles D.M., Woolf A.S., Cuckow P.M. Effects of in utero bladder outflow obstruction on fetal sheep detrusor contractility, compliance and innervation. Journal of Urology. 168:2002;1615-1620
30. Oberpenning F., Meng J., Yoo J.J., Atala A. De novo reconstitution of a functional mammalian urinary bladder by tissue engineering. Nature Biotechnology. 17:1999;149-155
31. Pariente J.L., Kim B.S., Atala A. In vitro biocompatibility assessment of naturally derived and synthetic biomaterials using normal human urothelial cells. Journal of Biomedical Materials Research. 55:2001;33-39
32. Pariente J.L., Kim B.S., Atala A. In vitro biocompatibility evaluation of naturally derived and synthetic biomaterials using normal human bladder smooth muscle cells. Journal of Urology. 167:2002;1867-1871
33. Peters C.A., Vasavada S., Dator D., Carr M., Shapiro E., Lepor H., McConnell J., Retik A.B., Mandell J. The effect of obstruction on the developing bladder. Journal of Urology. 148:1992;491-496
34. Roe B., Doll H. Prevalence of urinary incontinence and its relationship with health status. Journal of Clinical Nursing. 9:2000;178-187
35. Rohrmann D., Zderic S.A., Duckett J.W., Levin R.M. Compliance of the obstructed fetal rabbit bladder. Neurourology and Urodynamics. 16:1997;179-189
36. Saito M., Gotoh M., Kato K., Kondo A. Denervation supersensitivity of the rabbit urinary bladder to calcium ion. Journal of Urology. 142:1989;418-421
37. Scheepe J.R., Wipfler G., Schumacher S., Bross S., Zendler S., Juneman K.P., Alken P. Smooth muscle electromyography of the urinary bladder. Neurourology and Urodynamics. 17:1998;71-76
38. Schroder A., Chichester P., Kogan B.A., Longhurst P.A., Lieb J., Das A.K., Levin R.M. Effect of chronic bladder outlet obstruction on blood flow of the rabbit bladder. Journal of Urology. 165:2001;640-646
39. Sibley G.N. A comparison of spontaneous and nerve-mediated activity in bladder muscle from man pig and rabbit. Journal of Physiology. 354:1984;431-443
40. 2+ current. Journal of Urology. 165:2001;621-626
41. Sui G.P., Wu C., Fry C.H. The electrophysiological properties of cultured and freshly isolated detrusor smooth muscle cells. Journal of Urology. 165:2001;627-631
42. Sui G.P., Rothery S., Dupont E., Fry C.H., Severs N.J. Gap junctions and connexin expression in human sub-urothelial interstitial cells. British Journal of Urology International. 90:2002;118-129
43. Sui G.P., Wu C., Fry C.H. Electrical characteristics of sub-urothelial cells isolated from the human bladder. Journal of Urology. 171:2004;938-943
44. Temml C., Haidinger G., Schmidbauer J., Schatzl G., Madersbacher S. Urinary incontinence in both sexes: Prevalence rates and impact on quality of life and sexual life. Neurourology and Urodynamics. 19:2000;259-271
45. Thiruchelvam N., Nyirady P., Peebles D.M., Fry C.H., Cuckow P.M., Woolf A.S. Urinary outflow obstruction increases apoptosis and deregulates Bcl-2 and Bax expression in the fetal ovine bladder. American Journal of Pathology. 162:2003;1271-1282
46. Thiruchelvam N., Wu C., David A., Woolf A.S., Cuckow P.M., Fry C.H. Neurotransmission and viscoelasticity in the ovine fetal bladder after in utero bladder outflow obstruction. American Journal of Physiology. 284:2003;R1296-R1305
47. van Mastrigt R., Koopal J.W., Hak J., van de Wetering J. Modelling the contractility of urinary bladder smooth muscle using isometric contractions. American Journal of Physiology. 251:1986;R978-R983
48. Visser A.J., van Mastrigt R. Intracellular recording of spontaneous electrical activity in human urinary bladder smooth muscle strips. Archives of Physiology and Biochemistry. 107:1999;257-270
49. Wagg A., Fry C.H. Visco-elastic properties of isolated detrusor smooth muscle. Scandinavian Journal of Urology and Nephrology. 201:1999;S12-S18
50. Wilson L., Brown J.S., Shin G.P., Luc K.O., Subak L.L. Annual direct cost of urinary incontinence. Obstetrics and Gynecology. 98:2001;398-406
51. Wood, D.N. (2003). The development and characterisation of bladder tissue implants. PhD thesis, University of London.
52. 2+] and the contractile phenotype of cultured human detrusor smooth muscle cells. Journal of Urology. 171:2004;938-943. (In Press)
53. 2+-sensitivity in alpha-toxin permeabilized guinea pig detrusor muscle. Journal of Urology. 154:1995;1921-1924
54. 2+ stores in guinea-pig detrusor smooth muscle. Journal of Physiology. 538:2002;357-369