Scientific rationale for a change in the composition of oral rehydration solution

JAMA

Volumn 291, Issue 21, 2004, Pages 2628-2631

  Duggan, Christopher ^a   Fontaine, Olivier ^b   Pierce, Nathaniel F ^c   Glass, Roger I ^d   Mahalanabis, Dilip ^e   Alam, Nur Haque ^f   Bhan, Maharaj K ^g   Santosham, Mathuram ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^e SOCIETY FOR APPLIED STUDIES   (India)

^f ICDDRB Clinical Sciences Division   (Bangladesh)

^g ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ORAL REHYDRATION SOLUTION; BICARBONATE; GLUCOSE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; WORLD HEALTH ORGANIZATION ORAL REHYDRATION SOLUTION;

CHEMICAL COMPOSITION; DEVELOPING COUNTRY; DIARRHEA; ELECTROLYTE BALANCE; GLUCOSE TRANSPORT; HYPERNATREMIA; INTESTINE EPITHELIUM; ORAL REHYDRATION THERAPY; OSMOLARITY; PRIORITY JOURNAL; REVIEW; RISK BENEFIT ANALYSIS; SODIUM TRANSPORT; STOMACH EPITHELIUM; VIBRIO CHOLERAE; ARTICLE; FLUID THERAPY; HUMAN;

BICARBONATES; DIARRHEA; FLUID THERAPY; GLUCOSE; HUMANS; OSMOLAR CONCENTRATION; POTASSIUM CHLORIDE; REHYDRATION SOLUTIONS; SODIUM CHLORIDE;

EID: 2542457431     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.291.21.2628     Document Type: Review

References (46)

1. Black RE, Morris SS, Bryce J. Where and why are 10 million children dying every year? Lancet. 2003;361:2226-2234.
2. Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ. 2003;81:197-204.
3. Parashar U, Hummelman E, Bresee J, Miller M, Glass R. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis. 2003;9:565-572.
4. King CK, Glass R, Bresee JS, Duggan C; Centers for Disease Control and Prevention. Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy. MMWR Morb Mortal Wkly Rep. 2003;52(RR-16):1-16.
5. Snyder JD, Merson MH. The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bull World Health Organ. 1982;60:605-613.
6. Hirschhorn N, Greenough WB 3rd. Progress in oral rehydration therapy. Sci Am. 1991;264:50-56.
7. Victora CG, Bryce J, Fontaine O, Monasch R. Reducing deaths from diarrhoea through oral rehydration therapy. Bull World Health Organ. 2000;78:1246-1255.
8. Water with sugar and salt [editorial]. Lancet. 1978;2:300-301.
9. Pierce N, Banwell J, Mitra R, et al. Effect of intragastric glucose-electrolyte infusion upon water and electrolyte balance in Asiatic cholera. Gastroenterology. 1968;55:333-342.
10. Hirschhorn N, Kinzie J, Sachar D, et al. Decrease in net stool output in cholera during intestinal perfusion with glucose-containing solutions. N Engl J Med. 1968;279:176-181.
11. Field M. Intestinal ion transport and the pathophysiology of diarrhea. J Clin Invest. 2003;111:931-943.
12. Mahalanabis D, Choudri A, Bagchi N, et al. Oral fluid therapy of cholera among Bangladesh refugees. Johns Hopkins Med J. 1973;132:197-205.
13. Hirschhorn N, Cash R, Woodward W, Spivey G. Oral therapy of Apache children with acute infectious diarrhea. Lancet. 1972;1:15-18.
14. Santosham M, Daum RS, Dillman L, et al. Oral rehydration therapy of infantile diarrhea: a controlled study of well-nourished children hospitalized in the United States and Panama. N Engl J Med. 1982;306:1070-1076.
15. Hirschhorn N. The treatment of acute diarrhea in children: an historical and physiological perspective. Am J Clin Nutr. 1980;33:637-663.
16. Avery M, Snyder J. Oral therapy for acute diarrhea: the underused simple solution. N Engl J Med. 1990;323:891-894.
17. Molla A, Rahaman M, Sarker S, et al. Stool electrolyte content and purging rates in diarrhea caused by rotavirus, enterotoxigenic E. coli and V. cholerae in children. J Pediatr. 1981;98:835-838.
18. Nichols B, Soriano H. A critique of oral therapy of dehydration due to diarrheal syndromes. Am J Clin Nutr. 1977;30:1457.
19. Fayad IM, Hirichhorn N, Abu-Zikry M, Kamel M. Hypernatraemia surveillance during a national diarrhoeal diseases control project in Egypt. Lancet. 1992;339:389-393.
20. Nalin DR, Cash RA, Rahman M, Yunus M. Effect of glycine and glucose on sodium and water adsorption in patients with cholera. Gut. 1970;11:768-772.
21. Ribeiro H Jr, Ribeiro T, Mattos A, et al. Treatment of acute diarrhea with oral rehydration solutions containing glutamine. J Am Coll Nutr. 1994;13:251-255.
22. Molla AM, Molla A, Nath SK, Khatun M. Food-based oral rehydration salt solution for acute childhood diarrhoea. Lancet. 1989;2:429-431.
23. Fontaine O, Gore SM, Pierce NF. Rice-based oral rehydration solution for treating diarrhoea. Cochrane Database Syst Rev. 2000(2);CD001264.
24. Bhan MK, Mahalanabis D, Fontaine O, Pierce NF. Clinical trials of improved oral rehydration salt formulations: a review. Bull World Health Organ. 1994;72;945-955.
25. Santosham M, Burns BA, Reid R, et al. Glycine-based oral rehydration solution: reassessment of safety and efficacy. J Pediatr. 1986;109:795-801.
26. Thillainayagam AV, Hunt JB, Farthing MJ. Enhancing clinical efficacy of oral rehydration therapy: is low osmolality the key? Gastroenterology. 1998;114:197-210.
27. Farthing MJ. Disease-related animal models for optimising oral rehydration solution composition. Acta Paediatr Scand Suppl. 1989;364:23-30.
28. Hunt JB, Thillainayagam AV, Carnaby S, Fairclough PD, Clark ML, Farthing MJ. Absorption of a hypotonic oral rehydration solution in a human model of cholera. Gut. 1994;35:211-214.
29. el-Mougi M, el-Akkad N, Hendawi A, et al. Is a low-osmolarity ORS solution more efficacious than standard WHO ORS solution? J Pediatr Gastroenterol Nutr. 1994;19:83-86.
30. Santosham M, Fayad I, Abu Zikri M, et al. A double-blind clinical trial comparing World Health Organization oral rehydration solution with a reduced osmolarity solution containing equal amounts of sodium and glucose. J Pediatr. 1996;128:45-51.
31. Hahn S, Kim Y, Garner P. Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review. BMJ. 2001;323:81-85.
32. Alam NH, Majumder RN, Fuchs GJ; CHOICE Study group. Efficacy and safety of oral rehydration solution with reduced osmolarity in adults with cholera: a randomised double-blind clinical trial. Lancet. 1999;354:296-299.
33. CHOICE Study Group. Multicenter, randomized, double-blind clinical trial to evaluate the efficacy and safety of a reduced osmolarity oral rehydration salts solution in children with acute watery diarrhea. Pediatrics. 2001;107:613-618.
34. World Health Organization. Reduced Osmolarity Oral Rehydration Salts (ORS) Formulation. New York, NY: UNICEF House; July 18, 2001 2001. WHO/FCH/CAH/01.22.
35. Cash R, Hirschhorn N, Nalin D. Oral rehydration and hyponatraemia. Lancet. 1999;354:1733-1734.
36. Hirschhorn N, Nalin DR, Cash RA, Greenough WB 3rd. Formulation of oral rehydration solution. Lancet. 2002;360:340-341.
37. Hirschhorn N, Nalin DR, Cash RA. CHOICE Study Group trial. Pediatrics. 2002;109(4):713-715.
38. Dutta D, Bhattacharya MK, Deb AK, et al. Evaluation of oral hypo-osmolar glucose-based and rice-based oral rehydration solutions in the treatment of cholera in children. Acta Paediatr. 2000;89:787-790.
39. Alam S, Afzal K, Maheshwari M, Shukla I. Controlled trial of hypo-osmalar versus World Health Organization oral rehydration solution. Indian Pediatr. 2000;37:952-960.
40. Santosham M, Foster S, Reid R, et al. Role of soy-based, lactose-free formula during treatment of acute diarrhea. Pediatrics. 1985;76:292-298.
41. Brown KH, Gastañaduy AS, Saavedra JM, et al. Effect of continued oral feeding on clinical and nutritional outcomes of acute diarrhea in children. J Pediatr. 1988;112:191-200.
42. American Academy of Pediatrics Provisional Committee on Quality Improvement Subcommittee on Acute Gastroenteritis. Practice parameter: the management of acute gastroenteritis in young children. Pediatrics. 1996;97:424-436.
43. Duggan C, Nurko S. "Feeding the gut": the scientific basis for continued enteral nutrition during acute diarrhea. J Pediatr. 1997;131:801-808.
44. Penny ME. Protein-energy malnutrition: pathophysiology, clinical consequences, and treatment. In: Walker W, Watkins JB, Duggan C, eds. Nutrition in Pediatrics: Basic Science and Clinical Applications. 3rd ed. Hamilton, Ontario: BC Decker; 2003:174-194.
45. Dutta P, Mitra U, Manna B, et al. Double blind, randomised controlled clinical trial of hypo-osmolar oral rehydration salt solution in dehydrating acute diarrhoea in severely malnourished (marasmic) children. Arch Dis Child. 2001;84:237-240.
46. Sarker SA, Mahalanabis D, Alam NH, Sharmin S, Khan AM, Fuchs GJ. Reduced osmolarity oral rehydration solution for persistent diarrhea in infants: a randomized controlled clinical trial. J Pediatr. 2001;138:532-538.