Improved synthesis of a [4.4]-spirolactam β-turn mimetic as surrogate of the didemnin side chain dipeptide Pro-N-Me-D-Leu

Tetrahedron

Volumn 60, Issue 24, 2004, Pages 5177-5183

  Gutiérrez Rodríguez, Marta ^a   García López, M Teresa ^a   Herranz, Rosario ^a  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

Author keywords

Didemnins; Hemiaminal reduction; Mitsunobu type reaction; Peptidomimetics; Spirolactams; Turn mimetics

Indexed keywords

DIPEPTIDE; ION; LACTAM DERIVATIVE; LEUCINE; N TERT BUTYLOXYCARBONYL 2 ALLYLPROLINE; PEPTIDE; PROLYL N METHIONYLLEUCINE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; METHODOLOGY; OXIDATION; PRIORITY JOURNAL; REDUCTION;

EID: 2542445492     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.04.052     Document Type: Article

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