ω-pyridiniumalkylethers of steroidal phenols: New compounds with potent antibacterial and antiproliferative activities

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 12, 2004, Pages 3357-3362

  Lange, C ^a   Holzhey, N ^a   Schonecker B ^a   Beckert, R ^a   Mollmann U ^b   Dahse, H M ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b HANS KNÖLL INSTITUTE   (Germany)

Author keywords

Antimicrobial activity; Hybrid molecules; Pyridiniumalkyl salts; Steroids

Indexed keywords

1 (10' BROMODECYLOXY) 4 METHYLESTRA 1,3,5(10) TRIEN 17 ONE; 1 (4' BROMOBUTYLOXY) 4 METHYLESTRA 1,3,5(10) TRIEN 17 ONE; 1 (6' BROMOHEXYLOXY) 4 METHYLESTRA 1,3,5(10) TRIEN 17 ONE; 1 (8' BROMOOCTYLOXY) 4 METHYLESTRA 1,3,5(10) TRIEN 17 ONE; 3 (10' BROMODECYLOXY)ESTRA 1,3,5(10) TRIEN 17 ONE; 3 (4' BROMOBUTYLOXY)ESTRA 1,3,5(10) TRIEN 17 ONE; 3 (6' BROMOBUTYLOXY)ESTRA 1,3,5(10) TRIEN 17 ONE; 3 (8' BROMOBUTYLOXY)ESTRA 1,3,5(10) TRIEN 17 ONE; ALKANE DERIVATIVE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CARBON; CETYLPYRIDINIUM SALT; CIPROFLOXACIN; ETHER DERIVATIVE; N 1' [(17 OXOESTRA 1,3,5(10) TRIEN 3 YLOXY)BUTYL]PYRIDINIUM BROMIDE; N 1' [(17 OXOESTRA 1,3,5(10) TRIEN 3 YLOXY)HEXYL]PYRIDINIUM BROMIDE; N 1' [(17 OXOESTRA 1,3,5(10) TRIEN 3 YLOXY)OCTYL]PYRIDINIUM BROMIDE; N 1' [(4 METHYL 17 OXOESTRA 1,3,5(10) TRIEN 1 YLOXY)BUTYL]PYRIDINIUM BROMIDE; N 1' [(4 METHYL 17 OXOESTRA 1,3,5(10) TRIEN 1 YLOXY)DECYL]PYRIDINIUM BROMIDE; N 1' [(4 METHYL 17 OXOESTRA 1,3,5(10) TRIEN 1 YLOXY)HEXYL]PYRIDINIUM BROMIDE; N 1' [(4 METHYL 17 OXOESTRA 1,3,5(10) TRIEN 1 YLOXY)OCTYL]PYRIDINIUM BROMIDE; PYRIDINIUM DERIVATIVE; STEROID; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CYTOTOXICITY; ENTEROCOCCUS FAECALIS; HUMAN; HUMAN CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MYCOBACTERIUM; NONHUMAN;

ANTI-BACTERIAL AGENTS; CELL PROLIFERATION; ENTEROCOCCUS; ETHERS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PHENAZOPYRIDINE; PHENOLS; STAPHYLOCOCCUS AUREUS; STEROIDS;

CORYNEBACTERINEAE; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 2542434110     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.046     Document Type: Article

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