Practical use of alpha blockade strategy in the management of hypoplastic left heart syndrome following stage one palliation with a Blalock-Taussig shunt

Pediatric Cardiac Surgery Annual

Volumn 7, Issue 1, 2004, Pages 11-15

  De Oliveira, Nilto C ^a,b   Van Arsdell, Glen S ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NONE   (Canada)

Author keywords

Hypoplastic left heart syndrome (HLHS); Phenoxybenzamine; Sudden death

Indexed keywords

ADRENALIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; DOPAMINE; INOTROPIC AGENT; MILRINONE; NORADRENALIN; PHENOXYBENZAMINE; VASOPRESSIN;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ARTICLE; BLALOCK TAUSSIG ANASTOMOSIS; CHILD; CLINICAL PROTOCOL; DRUG HALF LIFE; DRUG INFUSION; DRUG MEGADOSE; DRUG RESPONSE; HEART MUSCLE OXYGEN CONSUMPTION; HEART OUTPUT; HEART SURGERY; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; HYPOTENSION; LOW DRUG DOSE; MEAN ARTERIAL PRESSURE; PALLIATIVE THERAPY; POSTOPERATIVE CARE; SIDE EFFECT; SUDDEN DEATH; SURGICAL TECHNIQUE; SYSTEMIC CIRCULATION; SYSTEMIC VASCULAR RESISTANCE; VASODILATATION; VENOUS OXYGEN TENSION;

EID: 2542433356     PISSN: 10929126     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.pcsu.2004.02.018     Document Type: Article

References (11)

1. Norwood WI, Lang P, Hansen DD: Physiologic repair of aortic atresia - Hypoplastic left heart syndrome. N Engl J Med 45:87-91, 1983
2. Iannetoni MD, Bove EL, Mosca RS, et al: Improving results with first stage palliation for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 107:934-340, 1994
3. Poirier NC, Jonathan JDW, Kunikazu H, et al: Modified Norwood procedure with a high-flox cardiopulmonary bypass strategy results in low mortality without late arch obstruction. J Thorac Cardiovasc Surg 120:875-884, 2000
4. Tweddell JS, Hoffman GM, Mussatto KA, et al: Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: Lessons learned from 115 consecutive patients. Circulation 106(suppl I):I-82-I-89, 2002
5. Tweddell JS, Hoffman GM, Fedderly RT, et al: Phenoxybenzamine improves systemic oxygen delivery after the Norwood procedure. Ann Thorac Surg 67:161-168, 1999
6. Hoffman BB, Lefkowitz RJ: Adrenergic Receptor Antagonists. Goodman and Gilman's The Pharmacological Basis of Therapeutics. New York, NY, Pergamon Press, 1991
7. O'Blenes SB, Roy N, Kostantinov I, et al: Vasopressin reversal of phenoxybenzamine induced hypotension after the Norwood procedure. J Thorac Cardiovasc Surg 123: 1012-1013, 2002
8. Holmes CL, Patel BM, Russell JA, et al: Physiology of vasopressin relevant to management of septic shock. Chest 120:989-1002, 2001
9. Hammel JM, Van Natta TL, Wang LX, et al: Cardioplegic arrest causes greater myocardial apoptosis in neonatal than mature lambs. Circulation 106:658, 2002 (suppl III) (abstr A3245)
10. Katz AM: The Working Heart. Physiology of the Heart. New York, NY, Lippincott, Williams and Wilkins, 2000
11. O'Blenes SB, Jegatheeswaran A, Campbell A, et al: Phenoxybenzamine induced vasodilation after the Norwood procedure. A comparison of vasopressin vs norepinephrine. Can J Cardiol 18:223B, 2002 (suppl B) (abstr A401)