Regulation of cytokine production in carcinoembryonic antigen stimulated Kupffer cells by β-2 adrenergic receptors: Implications for hepatic metastasis

Cancer Letters

Volumn 209, Issue 2, 2004, Pages 251-257

  Thomas, Peter ^a   Hayashi, Hiroshi ^a   Zimmer, Regis ^a   Forse, R Armour ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

2 Adrenergic receptors; Carcinoembryonic antigen; Hepatic metastasis; Kupffer cells

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CARCINOEMBRYONIC ANTIGEN; COMPLEMENTARY DNA; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TERBUTALINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; KUPFFER CELL; LIVER METASTASIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR IMMUNOLOGY; UPREGULATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; CARCINOEMBRYONIC ANTIGEN; CYTOKINES; GENE EXPRESSION PROFILING; INTERLEUKIN-10; INTERLEUKIN-6; KUPFFER CELLS; LIVER NEOPLASMS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TERBUTALINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2542432339     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2003.12.027     Document Type: Article

References (29)

1. Jessup J.M., Giavazzi R., Campbell D., Cleary K.R., Morikawa K., Fidler I.J. Growth potential of human colorectal carcinomas in nude mice: association with preoperative serum concentrations of carcinoembryonic antigen in patients. Cancer Res. 48:1988;1689-1692
2. Hostetter R.B., Augustus L.B., Mankarious R., Chi K., Fan D., Toth C.A., et al. Carcinoembryonic antigen as a selective enhancer of colorectal cancer metastases. J. Natl Cancer Inst. 82:1990;380-385
3. Hashino J., Fukada Y., Oikawa S., Nakazato H., Nakanishi T. Metastatic potential of human colorectal carcinoma SW1222 cells transfected with cDNA encoding carcinoembryonic antigen. Clin. Exp. Metastasis. 12:1994;324-328
4. Thomas P., Gangopadhyay A., Steele G., Andrews C., Nakazato H., Oikawa S., Jessup J.M. The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101. Cancer Lett. 92:1995;59-66
5. Toth C.A., Thomas P., Broitman S.A., Zamcheck N. A new Kupffer cell receptor mediating plasma clearance of carcinoembryonic antigen by the rat. Biochem. J. 204:1982;377-381
6. Toth C.A., Thomas P., Broitman S.A., Zamcheck N. Receptor mediated endocytosis of carcinoembryonic antigen by rat liver Kupffer cells. Cancer Res. 45:1985;392-397
7. Datar K.V., Dreyfuss G., Swanson M.S. The human hnRNP proteins: Identification of a methionine/arginine rich repeat motif in ribonucleoproteins. Nucleic Acids Res. 21:1993;339-446
8. Kafasla P., Patrinou-Georgoula M., A A. Guialis The 72/74-kDa polypeptides of the 70-110 S large heterogeneous nuclear ribonucleoprotein complex (LH-nRNP) represent a discrete subset of the hnRNP M protein family. Biochem. J. 350:2000;495-503
9. Bajenova O., Zimmer R., Stolper E., Salisbury-Rowswell J., Nanji A., Thomas P. HnRNP M4 is a Receptor for Carcinoembryonic Antigen in Kupffer Cells. J. Biol. Chem. 276:2001;31067-31073
10. Gangopadhyay A., Thomas P. Receptor mediated endocytosis of carcinoembryonic antigen by Kupffer cells: recognition of a penta-peptide sequence. Arch. Biochem. Biophys. 334:1996;151-157
11. Zimmer R., Thomas P. Mutations in the carcinoembryonic antigen gene in colorectal cancer patients: implications on liver metastasis. Cancer Res. 61:2001;2822-2826
12. Gangopadhyay A., Bajenova O., Kelly T.M., Thomas P. Carcinoembryonic antigen induces cytokine expression in Kupffer cells; implications for hepatic metastasis from colon cancer. Cancer Res. 56:1996;4805-4810
13. Gangopadhyay A., Lazure D.A., Thomas P. Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells. Clin. Exp. Metastasis. 16:1998;703-712
14. Jessup J.M., Petrick A.T., Toth C.A., Ford R., Meterissian S., O'Hara C.J., et al. Carcinoembryonic antigen: Enhancement of liver colonization through retention of human colorectal carcinoma cells. Br. J. Cancer. 67:1993;464-470
15. Decker K. Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192:1990;245-261
16. Toth C.A., Thomas P. Hepatic Endocytosis and Kupffer Cells. Hepatology. 16:1992;255-266
17. Zhou M., Yang S., Koo D.J., Ornan D.A., Chaudry I.H., Wang P. The role of Kupffer cell alpha(2)-adrenoceptors in norepinephrine-induced TNF-alpha production. Biochim. Biophys. Acta. 1537:2001;49-57
18. Yoshimura T., Kurita C., Nagao T., Usami E., Nakao T., Watanabe S., et al. Inhibition of tumor necrosis factor-alpha and Interleukin-1 beta production by beta-adrenoceptor agonists from lipopolysaccharide stimulated human peripheral blood mononuclear cells. Pharmacology. 54:1997;144-152
19. Linden M. The effects of beta-2-adrenoceptor agonists and a corticosteroid, budesonide, on the secretion of inflammatory mediators from monocytes. Br. J. Pharmacol. 107:1992;156-160
20. Shichijo M., Inagaki N., Kimata M., Serizawa I., Saito H., Nagai H. Role of cyclic 3′, 5′-adenosine monophosphate in the regulation of chemical mediator release and cytokine production from cultured human mast cells. J. Allergy Clin. Immunol. 103:1999;S421-S428
21. Hayashi H., Thomas P., Forse R.A. Effects of beta agonists on cytokine production in Kupffer cells. Surg. Forum. 87:2001;155-156
22. Nakamura A., Imaizumi A., Yanagawa Y., Niimi R., Kohsaka T. Suppression of tumor necrosis factor-alpha by beta(2)-adrenoceptor activation: role of mitogen-activated protein kinases in renal mesangial cells. Inflamm. Res. 52:2003;26-31
23. Yoshimura T. Modulation of cytokine production from human mononuclear cells by several agents. J. Pharm. Soc. Japan. 120:2000;1277-1290
24. Wu C.C., Liao M.H., Chen S.J., Chou T.C., Chen A., Yen M.H. Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia. Shock. 14:2000;66-67
25. Thomas P., Bajenova O., Zimmer R., Hayashi H., Forse R.A., Ganguly A. Kupffer cell carcinoembryonic antigen (CEA) interactions. A mechanism to enhance liver metastasis from CEA producing cancers. Cells of the Hepatic Sinusoid. vol. 8:2001;The Kupffer Cell Foundation, Rijswijk, The Netherlands. pp. 155-158
26. Seelander M.C., Kazantzis M., Costa Rosa L.F. The effect of adrenaline and Walker-256 induced cachexia upon Kupffer cell metabolism. Cell Biochem. Func. 17:1999;151-156
27. Quinn L.A., Moore G.E., Morgan R.T., Woods L.K. Cell lines from human colon carcinoma with unusual cell products, double minutes and homogeneously staining regions. Cancer Res. 39:1979;4914-4924
28. Belluco C., Nitti D., Frantz M., Toppan P., Basso D., Plebani M., et al. Interleukin-6 blood level is associated with circulating carcinoembryonic antigen and prognosis in patients with colorectal cancer. Ann. Surg. Oncol. 7:2000;133-138
29. Jessup J.M., Battle P., Lee K.H., Franz K.M. Carcinoembryonic Antigen (CEA) facilitates colonization of liver by colorectal carcinoma (CRC) through an IL-10 dependant mechanism. Proc. Am. Assoc. Cancer Res. 41:2000;590