Hepatocellular carcinoma in a patient with liver cirrhosis associated with negative serum HCV tests but positive liver tissue HCV RNA

Internal Medicine

Volumn 43, Issue 4, 2004, Pages 279-282

  Esaki, Tomoka ^a   Suzuki, Norihisa ^a   Yokoyama, Keiji ^a   Iwata, Kaoru ^a   Irie, Makoto ^a   Anan, Akira ^a   Nakane, Hidetoshi ^a   Yoshikane, Makoto ^a   Nishizawa, Shinya ^a   Ueda, Syuichi ^a   Sohda, Tetsuro ^a   Watanabe, Hiroshi ^a   Sakisaka, Shotaro ^a  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

HCV RNA; Hepatocellular carcinoma

Indexed keywords

DNA POLYMERASE; HEPATITIS C ANTIBODY; VIRUS RNA;

AGED; ANTIBODY DETECTION; ARTICLE; ARTIFICIAL EMBOLISM; BLOOD ANALYSIS; CASE REPORT; CATHETER ABLATION; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; ECHOGRAPHY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DYSFUNCTION; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TUMOR VOLUME;

AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; HEPATITIS C; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER NEOPLASMS; RNA, VIRAL; TOMOGRAPHY, X-RAY COMPUTED;

EID: 2542432227     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.43.279     Document Type: Article

References (16)

1. Journal of Health and Welfare Statistics. Health and Welfare Statistics Association, Tokyo, 2002: 50.
2. Primary Liver Cancer in Japan 14th, 2000. Liver Cancer Study Group in Japan, Tokyo, 2002: 38.
3. Saldanha J, Minor P. Incidence of hepatitis C virus RNA in anti-HCV-negative plasma pools and blood products. Vox Sang 70: 232-234, 1996.
4. Januszkiewicz-Lewandowska D, Wysocki J, Jozwiak H, Lewandowski K, Rembowska J, Nowak J. Significance of molecular identification of hepatitis C virus RNA in diagnosis of cryptogenic hepatitis in children. Acta Virol 45: 257-260, 2001.
5. Alvarez F, Berg PA, Bianchi FB, et al. International autoimmune hepatitis group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 31: 929-938, 1999.
6. Lee LG, Connell CR, Bloch W. Allelic discrimination by nick-translation PCR with fluorogenic probes. Nucl Acids Res 6: 3761-3766, 1993.
7. Takeuchi T, Katsume A, Tanaka T, et al. Real-time detection system for quantification of hepatitis C virus genome. Gastroenterology 116: 636-642, 1999.
8. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate phenol-chloroform extraction. Ann Biochem 162: 156-159, 1987.
9. Colantoni A, De Maria N, Idilman R, Van Thiel DH. Polymerase chain reaction for the detection of HCV-RNA: cryoglobulinaermia as a cause for false negative results. Ital J Gastroenterol Hepatol 29: 273-274, 1997.
10. Schmidt WN, Wu P, Cederna J, Mitres FA, La Brecque DR, Stapleton JT. Surreptitious hepatitis C virus (HCV) infection detected in the majority of patients with cryptogenic chronic hepatitis and negative HCV antibody tests. J Infect Dis 176: 27-33, 1997.
11. Das U, Kar P, Gopalkrishna V, Sharma JK, Madan K, Das BC. Comparative evaluation of hepatitis C virus infection in serum and liver tissue of patients with chronic liver disease by reverse transcription-polymerase chain reaction. Clin Microbiol Infect 5: 256-261, 1999.
12. Feucht HH, Zollner B, Schroter M, et al. High rate of chronicity in HCV infection determined by antibody confirmatory assay and PCR in 4110 patients during long-term follow up. J Clin Virol 13: 43-51, 1999.
13. Okanoue T, Kiyosawa K. The Actual Circumstances of Liver Cirrhosis in Japan 1998. Chugai-Igaku, Co., Tokyo, 1990: 1-5.
14. Chan HL, Tsang SW, Leung NW, et al. Occult HBV infection in cryptogenic liver cirrhosis in an area with high prevalence of HBV infection. Am J Gastroenterol 97: 1211-1215, 2002.
15. Marrero JA, Fontana RJ, Su GL, Conjeevaram HS, Emick DM, Lok AS. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 36: 1349-1354, 2002.
16. Bugianesi E, Leone N, Vanni E, et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 123: 134-140, 2002.