Separation of Tröger's base enantiomers through a combination of simulated moving bed chromatography and crystallization

Adsorption

Volumn 11, Issue 1 SUPPL., 2005, Pages 893-897

  Amanullah, Mohammad ^a   Abel, Stefanie ^a   Mazzotti, Marco ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Crystallization; Hybrid process; Simulated moving bed; Tr ger's base

Indexed keywords

ADSORPTION ISOTHERMS; CELLULOSE; CHROMATOGRAPHIC ANALYSIS; CRYSTALLIZATION; ETHANOL; EVAPORATION; GENETIC ALGORITHMS; THERMODYNAMICS;

CELLULOSE TRIACETATE (CTA); ENANTIOMERS; EVAPORATIVE CRYSTALLIZATION; SIMULATED MOVING BED (SMB) CHROMATOGRAPHY;

SEPARATION;

ALGORITHMS; CELLULOSE; CHROMATOGRAPHY; CRYSTALLIZATION; ETHANOL; EVAPORATION; SEPARATION; THERMODYNAMICS;

EID: 25144524223     PISSN: 09295607     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10450-005-6042-0     Document Type: Conference Paper

References (8)

1. Jacques, J. and A. Collet, Enantiomers, Racemates and Resolution, Wiley & Sons, New York, 1981.
2. Juza, M., M. Mazzotti, and M. Morbidelli, "Simulated Moving-Bed Chromatography and its Application to Chirotechnology," Trends Biotechnol., 18, 108-118 (2000).
3. Lim, E.G., C.B. Ching, R.B.H. Tan, and S.C. Ng, "Recovery of (-)-Praziquantel from Racemic Mixtures by Continuous Chromatography and Crystallization," Chem. Eng. Sci., 50, 2289-2298 (1995).
4. Lorenz, H., P. Sheehan, and A. Seidel-Morgenstern, "Coupling of Simulated Moving Bed Chromatography and Fractional Crystallisation for Efficient Enantioseparation," J. Chromatogr. A, 908, 201-214 (2001).
5. Migliorini, C., M. Mazzotti, G. Zenoni, M.P. Pedeferri, and M. Morbidelli, "Modeling Chromatographic Chiral Separations under Nonlinear Competitive Conditions," AIChE J., 46, 1530-1540 (2000).
6. Pedeferri, M., G. Zenoni, M. Mazzotti, and M. Morbidelli, "Experimental Analysis of a Chiral Separation Through Simulated Moving Bed Chromatography," Chem. Eng. Sci., 54, 3735-3748 (1999).
7. Worlitschek, J., M. Bosco, M. Huber, V. Gramlich, and M. Mazzotti, "Solid-Liquid Equilibrium of Troger's Base Enantiomers in Ethanol: Experiments and Modelling," Helvetica Chimica Acta, 87, 279-291 (2004).
8. Zhang, Z., M. Mazzotti, and M. Morbidelli, "Multiobjective Optimization of Simulated Moving Bed and Varicol Processes using a Genetic Algorithm," J. Chromatogr. A, 989, 95-108 (2003).