Hange-koboku-to, a kampo medicine, modulates cerebral levels of 5-HT (5-hydroxytryptamine), NA (noradrenaline) and DA (dopamine) in mice

Phytotherapy Research

Volumn 19, Issue 6, 2005, Pages 491-495

  Kaneko, Akiyo ^a   Cho, Shigefumi ^a   Hirai, Koichi ^a   Okabe, Tetsuro ^a   Iwasaki, Koh ^b   Nanba, Yoshio ^a   Ouchi, Yasuyoshi ^a   Cyong, Jong Chol ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JUNTENDO UNIVERSITY   (Japan)

Author keywords

Antidepressant; Anxiety; Depression; Herbal medicine; Swallowing disturbance

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; BENZODIAZEPINE DERIVATIVE; DOPAMINE; HANGE KOBOKU TO; HOMOVANILLIC ACID; KAMPO; MONOAMINE; MONOAMINE OXIDASE INHIBITOR; NORADRENALIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DEPRESSION; DRUG EFFECT; DRUG EFFICACY; DYSPHAGIA; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS; MALE; MENTAL DISEASE; MONOAMINERGIC SYSTEM; MOUSE; NEUROLOGIC DISEASE; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; ANTI-ANXIETY AGENTS; DOPAMINE; DRUGS, CHINESE HERBAL; MALE; MEDICINE, KAMPO; MICE; MICE, INBRED C57BL; NOREPINEPHRINE; PHYTOTHERAPY; SEROTONIN; TELENCEPHALON;

EID: 25144500745     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1669     Document Type: Article

References (21)

1. Butterweck V, Bockers T, Korte B, Wittkowski W, Winterhoff H. 2002. Long-term effects of St. John's wort and hypericin on monoamine levels in rat hypothalamus and hippocampus. Brain Res 930: 21-29.
2. D'haenen HA, Bossuyt A. 1994. Dopamine D2 receptors in depression measured with single photon emission computed tomography. Biol Psychiatry 35(2): 128-132.
3. Hall LM, Anderson GM, Cohen DJ. 1995. Acute and chronic effects of fluoxetine and haloperidol on mouse brain serotonin and norepinephrine turnover. Life Sci 57: 791-801.
4. Hrdina PD. 1987. Regulation of high- and low-affinity [3H] imipramine recognition sites in rat brain by chronic treatment with antidepressants. Eur J Pharmacol 138: 159-168.
5. Hisanaga A, Itoh T, Hasegawa Y, et al. 2002. A case of sleep choking syndrome improved by the Kampo extract of Hangekoboku-to. Psychiatry Clin Neurosci 56: 325-327.
6. Iwasaki K, Wang Q, Nakagawa T, Suzuki T, Sasaki H. 1999. The traditional Chinese medicine Banxia Houpo Tang improves swallowing reflex. Phytomedicine 6: 103-106.
7. Iwasaki K, Wang Q, Seki H, et al. 2000. The effects of the traditional Chinese medicine, 'Banxia Houpo Tang (HangeKoboku-To)' on the swallowing reflex in Parkinson's disease. Phytomedicine 7: 259-263.
8. Karoum F, Korpi ER, Linnoila M, Chuang LW, Wyatt RJ. 1984. Reduced metabolism and turnover rates of rat brain dopamine, norepinephrine and serotonin by chronic desipramine and zimelidine treatments. Eur J Pharmacol 100(2): 137-144.
9. Kobayashi H, Nakagawa T, Sekizawa K, Arai H, Sasaki H. 1996. Levodopa and swallowing reflex. Lancet 348: 1320-1321.
10. Luo L, Wang JN, Kong LD, Jiang QG, Tan RX. 2000. Anti-depressant effects of Banxia Houpe decoction, a traditional Chinese medicinal empirical formula. J Ethnopharmacol 73: 277-281.
11. Mantani N, Hisanaga A, Kogure T, Kita T, Shimada Y, Terasawa K. 2002. Four cases of panic disorder successfully treated with Kampo (Japanese herbal) medicines: Kami-shoyo-san and Hange-koboku-to. Psychiatry Clin Neurosci 56: 617-620.
12. Maruyama Y, Kuribara H, Morita M, Tuzurihara M, Weintraub ST. 1998. Identification of magnolol and honokiol as anxiolytic agents in extracts of saiboku-to, an oriental herbal medicine. J Nat Prod 61: 135-138.
13. Meyer JM, Krüger S, Wilson AA, Christensen BK, Goulding VS, Schaffer A, Minifie C, Houle S, Hussey D, Kennedy SH. 2001. Lower dopamine transporter binding potential in striatum during depression. Neuroreport 12(18): 4121-4125.
14. Nakagawa T, Sekizawa K, Arai H, Kikuchi R, Manabe K, Sasaki H. 1997. High incidence of pneumonia in elderly patients with basal ganglia infarction. Arch Intern Med 157: 321-324.
15. Nakazawa T, Yasuda T, Ohsawa K. 2003a. Metabolites of orally administered Magnolia officinalis extract in rats and man and its antidepressant-like effects in mice. J Pharm Pharmacol 55: 1583-1591.
16. Nakazawa T, Yasuda T, Ueda J, Ohsawa K. 2003b. Antidepressant-like effects of apigenin and 2,4,5-trimethoxycinnamic acid from Perilla frutescens in the forced swimming test. Biol Pharm Bull 26: 474-480.
17. Rosloff BN, Davis JM. 1978. Decrease in brain NE turnover after chronic DMI treatment: No effect with iprindole. Psychopharmacology 56: 335-341.
18. Sugrue MF. 1980. Changes in rat brain monoamine turnover following chronic antidepressant administration. Life Sci 26: 423-429.
19. Takeda H, Tsuji M, Inazu M, Egashira T, Matsumiya T. 2002. Rosmarinic acid and caffeic acid produce antidepressive-like effect in forced swimming test in mice. Eur J Pharmacol 449: 261-267.
20. Takeichi M, Sato T. 1999. Studies on the psychosomatic functioning of ill-health according to Eastern and Western medicine. 3. Two treatment methods using kampo medication for stress-related and lifestyle diseases. Am J Chin Med 27: 315-329.
21. Trouvin JH, Gardier AM, Chanut E, Pages N, Jacquot C. 1993. Time course of brain serotonin metabolism after cessation of long-term fluoxetine treatment in the rat. Life Sci 52: 187-192.