Cutaneous periumbilical purpura in disseminated strongyloidiasis in cancer patients: A pathognomonic feature of potentially lethal disease?

Brazilian Journal of Infectious Diseases

Volumn 9, Issue 5, 2005, Pages 419-424

  Salluh, Jorge I F ^a,b,c   Bozza, Fernando A ^b   Pinto, Tatiana S ^a   Toscano, Luisa ^a   Weller, Peter F ^d   Soares, Marcio ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Hospital Barra D'Or   (Brazil)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cancer; Corticosteroids; Disseminated strongyloidiasis; Purpura; Sepsis

Indexed keywords

ALBENDAZOLE; ANTHELMINTIC AGENT; IVERMECTIN; STEROID; TIABENDAZOLE;

ACUTE RESPIRATORY FAILURE; ADULT; AGED; ARTICLE; CANCER; CANCER THERAPY; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; HUMAN; MALE; PROPHYLAXIS; PURPURA; SEPTIC SHOCK; STRONGYLOIDES; STRONGYLOIDIASIS;

EID: 25144491413     PISSN: 14138670     EISSN: 14138670     Source Type: Journal    
DOI: 10.1590/S1413-86702005000500010     Document Type: Article

References (22)

1. Siddiqui A.A., Berk S.L. Diagnosis of Strongyloides stercoralis infection. Clin Infect Dis 2001;33:1040-7.
2. Stone W.J., Schaffner W. Strongyloides infections in transplant recipients. Semin Respir Infect 1990;5:58-64.
3. Ly M.N., Bethel S.L., Usmani A.S., Lambert D.R. Cutaneous Strongyloides stercoralis infection: an unusual presentation. J Am Acad Dermatol 2003;49(Suppl 2):S157-160.
4. Purvis R.S., Beightler E.L., Diven D.G., et al. Strongyloides hyperinfection presenting with petechiae and purpura. Int J Dermatol 1992;31:169-71.
5. Reddy T.S. Syndrome of inappropriate secretion of antidiuretic hormone and nonpalpable purpura in a woman with Strongyloides stercoralis hyperinfection. Am J Med Sci 2003;325:288-91.
6. Ronan S.G., Reddy R.L., Manaligod J.R., et al. Disseminated strongyloidiasis presenting as purpura. J Am Acad Dermatol 1989;21:1123-5.
7. Kalb R.E., Grossman M.E. Periumbilical purpura in disseminated strongyloidiasis. JAMA 1986;256:1170-1.
8. von Kuster L.C., Genta R.M. Cutaneous manifestations of strongyloidiasis. Arch Dermatol 1988;124:1826-30.
9. Williams J., Nunley D., Dralle W., et al. Diagnosis of pulmonary strongyloidiasis by bronchoalveolar lavage. Chest 1988;94:643-4.
10. Mahmoud A.A.F. Strongyloidiasis. Clin Infect Dis 1996;23:949-52.
11. Genta R.M. Dysregulation of strongyloidiasis: a new hypothesis. Clin Microbiol Rev 1992;5:345-55.
12. Siddiqui A.A., Stanley C.S., Skelly P.J., Berk S.L. A cDNA encoding a nuclear hormone receptor of the steroid/thyroid hormone-receptor superfamily from the human parasitic nematode Strongyloides stercoralis. Parasitol Res 2000;86:24-9.
13. Liu L.X., Weller P.F. Strongyloidiasis and other intestinal nematode infections. Infect Dis Clin North Am 1993;7:655-82.
14. Portugal R., Schaffel R., Almeida L., et al. Thiabendazole for the prophylaxis of strongyloidiasis in immunosuppressed patients with hematological diseases: a randomized double-blind placebo-controlled study. Haematologica 2002;87:663-4.
15. Muenning P., Pallin D., Sell R.L., Chan M.-S. The cost effectiveness of strategies for the treatment of intestinal parasites in immigrants. New Engl J Med 1999;340:773-9.
16. Grove D.I. Treatment of strongyloidiasis with thiabendazole: an analysis of toxicity and effectiveness. Trans R Soc Trop Med Hyg 1982;76:114-8.
17. Gann P.H., Neva F.A., Gam A.A. A randomized trial of single- and two-dose ivermectin versus thiabendazole for treatment of strongyloidiasis. J Infect Dis 1994;169:1076-9.
18. Marti H., Haji H.J., Savioli L., et al. A comparative trial of a single-dose ivermectin versus three days of albendazole for treatment of Strongyloides stercoralis and other soil-transmitted helminth infections in children. Am J Trop Med Hyg 1996;55:477-81.
19. Liu L.X., Weller P.F. Antiparasitic drugs. N Engl J Med 1996;334:1178-84.
20. Keiser P.B., Nutman T.B. Strongyloides stercoralis in the immunocompromised population. Clin Microbiol Rev 2004;17:208-17.
21. Cimerman S., Cimerman B., Lewi D.S. Prevalence of intestinal parasitic infections in patients with acquired immunodeficiency syndrome in Brazil. Int J Infect Dis 1999;3:203-6.
22. Chiodini P.L., Reid A.J., Wiselka M.J., et al. Parenteral ivermectin in Strongyloides hyperinfection. Lancet 2000;355 43-4.