Insulin sensitivity derived from oral glucose tolerance testing in athletes: Disagreement between available indices

Journal of Sports Sciences

Volumn 23, Issue 10, 2005, Pages 1065-1073

  Niakaris, Konstantinos ^a   Magkos, Faidon ^b   Geladas, Nikos ^a   Sidossis, Labros S ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b HAROKOPIO UNIVERSITY   (Greece)

Author keywords

Athletes; Endurance; Glucose tolerance; Insulin sensitivity; Oral glucose tolerance test; Sprint

Indexed keywords

ADULT; ARTICLE; ATHLETE; BODY COMPOSITION; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; ENDURANCE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INSULINEMIA; MALE; ORAL GLUCOSE TOLERANCE TEST; PHYSICAL ACTIVITY; RUNNING; SPORT;

ADULT; ANALYSIS OF VARIANCE; GLUCOSE TOLERANCE TEST; HUMANS; MALE; PHYSICAL FITNESS; RUNNING; SENSITIVITY AND SPECIFICITY;

EID: 25144490030     PISSN: 02640414     EISSN: 1466447X     Source Type: Journal    
DOI: 10.1080/02640410400023241     Document Type: Article

References (30)

1. Avignon, A., Boegner, C., Mariano-Goulart, D., Colette, C., & Monnier, L. (1999). Assessment of insulin sensitivity from plasma insulin and glucose in the fasting or post oral glucose-load state. International Journal of Obesity and Related Metabolic Disorders, 23, 512-517.
2. Bjorntorp, P., Fahlen, M., Grimby, G., Gustafson, A., Holm, J., Renstrom, P. et al. (1972). Carbohydrate and lipid metabolism in middle-aged, physically well-trained men. Metabolism, 21, 1037-1044.
3. Borghouts, L. B., & Keizer, H. A. (2000). Exercise and insulin sensitivity: A review. International Journal of Sports Medicine, 21, 1-12.
4. DeFronzo, R. A., Tobin, J. D., & Andres, R. (1979). Glucose clamp technique: A method for quantifying insulin secretion and resistance. American Journal of Physiology, 237, E214-E223.
5. Duncan, G. E., Hutson, A. D., & Stacpoole, P. W. (2001). QUICKI does not accurately reflect changes in insulin sensitivity with exercise training. Journal of Clinical Endocrinology and Metabolism, 86, 4115-4119.
6. Duncan, G. E., Hutson, A. D., & Stacpoole, P. W. (2002). QUICKI is not a useful and accurate index of insulin sensitivity following exercise training. Journal of Clinical Endocrinology and Metabolism, 87, 950-951.
7. Eriksson, J., Tuominen, J., Valle, T., Sundberg, S., Sovijarvi, A., Lindholm, H. et al. (1998). Aerobic endurance exercise or circuit-type resistance training for individuals with impaired glucose tolerance? Hormone and Metabolic Research, 30, 37-41.
8. Fenicchia, L. M., Kanaley, J. A., Azevedo, J. L., Jr., Miller, C. S., Weinstock, R. S., Carhart, R. L. et al. (2004). Influence of resistance exercise training on glucose control in women with type 2 diabetes. Metabolism, 53, 284-289.
9. Fujitani, J., Higaki, Y., Kagawa, T., Sakamoto, M., Kiyonaga, A., Shindo, M. et al. (1998). Intravenous glucose tolerance test-derived glucose effectiveness in strength-trained humans. Metabolism, 47, 874-877.
10. Gippini, A., Mato, A., Pazos, R., Suarez, B., Vila, B., Gayoso, P. et al. (2002). Effect of long-term strength training on glucose metabolism: Implications for individual impact of high lean mass and high fat mass on relationship between BMI and insulin sensitivity. Journal of Endocrinological Investigation, 25, 520-525.
11. Goodyear, L. J., & Kahn, B. B. (1998). Exercise, glucose transport, and insulin sensitivity. Annual Review of Medicine, 49, 235-261.
12. Gutt, M., Davis, C. L., Spitzer, S. B., Llabre, M. M., Kumar, M., Czarnecki, E. M. et al. (2000). Validation of the insulin sensitivity index (ISI(0,120)): Comparison with other measures. Diabetes Research and Clinical Practice, 47, 177-184.
13. Henriksen, E. J. (2002). Effects of acute exercise and exercise training on insulin resistance. Journal of Applied Physiology, 93, 788-796.
14. Holten, M. K., Zacho, M., Gaster, M., Juel, C., Wojtaszewski, J. F., & Dela, F. (2004). Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes, 53, 294-305.
15. Ishii, T., Yamakita, T., Sato, T., Tanaka, S., & Fujii, S. (1998). Resistance training improves insulin sensitivity in NIDDM subjects without altering maximal oxygen uptake. Diabetes Care, 21, 1353-1355.
16. Katz, A., Nambi, S. S., Mather, K., Baron, A. D., Follmann, D. A., Sullivan, G. et al. (2000). Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans. Journal of Clinical Endocrinology and Metabolism, 85, 2402-2410.
17. King, D. S., Dalsky, G. P., Staten, M. A., Clutter, W. E., Van Houten, D. R., & Holloszy, J. O. (1987). Insulin action and secretion in endurance-trained and untrained humans. Journal of Applied Physiology, 63, 2247-2252.
18. Levine, R., & Haft, D. E. (1970). Carbohydrate homeostasis. New England Journal of Medicine, 283, 237-246.
19. Lohmann, D., Liebold, F., Heilmann, W., Senger, H., & Pohl, A. (1978). Diminished insulin response in highly trained athletes. Metabolism, 27, 521-524.
20. Matsuda, M., & DeFronzo, R. A. (1999). Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp. Diabetes Care, 22, 1462-1470.
21. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985). Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419.
22. Miller, J. P., Pratley, R. E., Goldberg, A. P., Gordon, P., Rubin, M., Treuth, M. S. et al. (1994). Strength training increases insulin action in healthy 50- to 65-yr-old men. Journal of Applied Physiology, 77, 1122-1127.
23. Poehlman, E. T., Dvorak, R. V., DeNino, W. F., Brochu, M., & Ades, P. A. (2000). Effects of resistance training and endurance training on insulin sensitivity in nonobese, young women: A controlled randomized trial. Journal of Clinical Endocrinology and Metabolism, 85, 2463-2468.
24. Reynolds, T. H., Supiano, M. A., & Dengel, D. R. (2004). Resistance training enhances insulin-mediated glucose disposal with minimal effect on the tumor necrosis factor-α system in older hypertensives. Metabolism, 53, 397-402.
25. Ryan, A. S., Pratley, R. E., Goldberg, A. P., & Elahi, D. (1996). Resistive training increases insulin action in postmenopausal women. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 51, M199-M205.
26. Seltzer, H. S., Allen, E. W., Herron, A. L., Jr., & Brennan, M. T. (1967). Insulin secretion in response to glycemic stimulus: Relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus. Journal of Clinical Investigation, 46, 323-335.
27. Takala, T. O., Nuutila, P., Knuuti, J., Luotolahti, M., & Yki-Jarvinen, H. (1999). Insulin action on heart and skeletal muscle glucose uptake in weight lifters and endurance athletes. American Journal of Physiology, 276, E706-E711.
28. Wojtaszewski, J. F., Jorgensen, S. B., Frosig, C., MacDonald, C., Birk, J. B., & Richter, E. A. (2003). Insulin signalling: Effects of prior exercise. Acta Physiologica Scandinavica, 178, 321-328.
29. Yki-Jarvinen, H. and Koivisto, V. A. (1983). Effects of body composition on insulin sensitivity. Diabetes, 32, 965-969.
30. Zachwieja, J. J., Toffolo, G., Cobelli, C., Bier, D. M., & Yarasheski, K. E. (1996). Resistance exercise and growth hormone administration in older men: Effects on insulin sensitivity and secretion during a stable-label intravenous glucose tolerance test. Metabolism, 45, 254-260.