Alkoxyresorufin-O-deethylase activities and polychlorinated biphenyl patterns in shrews as biomarkers in environmental risk assessments: Sensitivity and specificity

Environmental Science and Technology

Volumn 39, Issue 18, 2005, Pages 7337-7343

  Van Den Brink, Nico W ^a   Bosveld, Albertus T C ^a,b  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b SETAC Europe   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOMARKERS;

AROD; DIOXIN-LIKE COMPOUNDS; GENDER-SPECIFIC INDUCTION; POLYCHLORINATED BIPHENYL (PCB);

ENZYMES;

BIOLOGICAL MARKER; DIOXIN; ETHOXYRESORUFIN DEETHYLASE; ORGANOCHLORINE DERIVATIVE; POLYCHLORINATED BIPHENYL;

BIOINDICATOR; BIOMARKER; ENVIRONMENTAL RISK; INSECTIVORE; PCB; RISK ASSESSMENT;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; ENZYME SPECIFICITY; EVALUATION; FEMALE; FIELD EXPERIMENT; IN VIVO STUDY; INSECTIVORE; LOGISTIC REGRESSION ANALYSIS; MALE; METABOLISM; NONHUMAN; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; VALIDATION PROCESS;

ANIMALS; BIOLOGICAL MARKERS; CHLORINE; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FEMALE; LIPIDS; LOGISTIC MODELS; MALE; MODELS, THEORETICAL; POLYCHLORINATED BIPHENYLS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEX FACTORS; SHREWS;

ANIMALIA; SORICIDAE;

EID: 25144464507     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es0504688     Document Type: Article

References (35)

1. Calow, P. Environmental risk assessment and management: The whats, whys and hows? In Handbook of Environmental Risk Assessment and Management; Calow, P., Ed.; Blackwell Science: Oxford, U.K., 1998.
2. Morgan, A. J.; Morgan, J. E.; Turner, M.; Winters, C.; Yarwood, A. Metal relationships of earthworms. In Ecotoxicology of Metals in Invertebrates; Dallinger, R., Rainbow, P. S., Eds.; Lewis Publishers: Boca Raton, FL, 1993.
3. Van den Brink, N. W.; Groen, N. M.; De Jonge, J.; Bosveld, A. T. C. Ecotoxicological suitability of floodplain habitats in The Netherlands for the little owl (Athene noctua vidalli). Environ. Fallut. 2003, 122 (1), 127-134.
4. Goszczynski, J.; Jedrzejewska, B.; Jedrzejewski, W. Diet composition of badgers (Meles meles) in a pristine forest and rural habitats of Poland compared to other European populations. J. Zool. 2000, 250 (4), 495-505.
5. Butterfield, J.; Coulson, J. C.; Wanless, S. Studies on the distribution, food, breeding biology and relative abundance of the pygme and sorex shrews (Sorex minutus and S. araneus) in upland areas of northern England. J. Zool. 1981, 195, 169-180.
6. Saarikko, J. Foraging behavior of shrews. Ann. Bot. Fenn. 1989, 26, 441-423.
7. Ma, W. C.; Denneman, W.; Faber, J. Hazardous exposure of ground-living small mammals to cadmium and lead in contaminated terrestrial ecosystems. Arch. Environ. Contam. Toxicol. 1991, 20 (2), 266-270.
8. Hamers, T.; Smit, L. A. M.; Bosveld, A. T. C.; van den Berg, J. H. J.; Koeman, J. H.; van Schooten, F. J.; Murk, A. J. Lack of a distinct gradient in biomarker responses in small mammals collected at different distances from a highway. Arch. Environ. Contam. Toxicol. 2002, 43 (3), 345-355.
9. Reinecke, A. J.; Reinecke, S. A.; Musilbono, D. E.; Chapman, A. The transfer of lead (Pb) from earthworms to shrews (Myosorex varius). Arch. Environ. Contam. Toxicol. 2000, 39 (3), 392-397.
10. Russell, J. S.; Halbrook, R. S.; Woolf, A.; French, J. B.; Melancon, MJ. Blarina brevicauda as biological monitor of polychlorinated biphenyls: Evaluation of hepatic cytochrome P450 induction. Environ. Toxicol. Chem. 2004, 23 (8), 1867-1873.
11. Van der Oost, R.; Beyer, J.; Vermeulen, N. P. E. Fish bioaccumulation and biomarkers in environmental risk assessment: A review. Environ. Toxicol. Pharmacol. 2003, 13 (2), 57-149.
12. Blankenship, A. L.; Giesy, J. P. Use of biomarkers of exposure and vertebrate tissue residues in the hazard characterization of PCBs at contaminated sites-Application to birds and mammals. Environ. Anal. Contam. Sites 2002, 153-180.
13. Van den Brink, N. W.; De Ruiter Dijkman, E. M.; Broekhuizen, S.; Reijnders, P. J. H.; Bosveld, A. T. C. Polychlorinated biphenyls pattern analysis: Potential nondestructive biomarker in vertebrates for exposure to cytochrome P450-inducing organochlorines. Environ. Toxicol. Chem. 2000, 19 (3), 575-581.
14. Boon, J. P.; Van der Meer, J.; Allchin, C. R.; Law, R. J.; Klungsøyr, J.; Leonards, P. E. G.; Spliid, H.; Storr-Hansen, E.; Mckenzie, C.; Wells, D. E. Concentration-dependent changes of PCB patterns in fish-eating mammals: structural evidence for induction of cytochrome P450. Arch. Environ. Contam. Toxicol. 1997, 33, 298-311.
15. Shimada, T.; Sawabe, Y. Activation of 3,4,3′,4′- tetrachlorobiphenyl to protein-bound metabolites by rat liver microsomal cytochrom P448 containing monooxygenase system. Toxicol. Appl. Pharmacol. 1983, 70, 486-943.
16. Murk, A. J.; Morse, D.; Boon, J. P.; Brouwer, A. In vitro metabolism of 3,3′,4,4′-tetrachlorobiphenyl in relation to ethoxyresorufin-O- deethylase activity in liver microsomes of some wildlife species and rat. Eur. J. Pharmacol., Environ. Toxicol. Pharmacol. Sect. 1994, 3 (2-3), 253-261.
17. Heidmann, W. A.; Staats de Yanes, G.; Büthe, A.; Rüssel-Sinn, H. Correlation between concentration and composition of PCB mixtures in seals (Phoca vitulina). Chem.-Eur. J. 1992, 24, 1111-1117.
18. Van den Brink, N. W.; Bosveld, A. T. C. PCB concentrations and metabolism patterns in common terns (Sterna hirundo) from different breeding colonies in The Netherlands. Mar. Pollut. Bull. 2001, 42 (4), 280-285.
19. Kennedy, S. W.; Lorenzen, A. A fluorescence-based protein assay for use with a microplate reader. Anal. Biochem. 1993, 214, 346-348.
20. Lane, P. W. Regression analysis. In Genstat 5, Release 3: Reference Manual; Genstat 5 Committee, Ed.; Oxford Science Publications: Oxford, U.K., 1993.
21. Payne, R. W. Design and analysis of experiments. In Genstat 5, Releases: Reference Manual; Genstat 5 Committee, Ed.; Oxford Science Publications: Oxford, U.K., 1993.
22. Brunstrom, B.; Lund, B. O.; Bergman, A.; Asplund, L.; Athanassiadis, I.; Athanasiadou, M.; Jensen, S.; Orberg, J. Reproductive toxicity in mink (Mustela vison) chronically exposed to environmentally relevant polychlorinated biphenyl concentrations. Environ. Toxicol. Chem. 2001, 20 (10), 2318-2327.
23. Halbrook, R. S.; Aulerich, R. J.; Bursian, S. J.; Lewis, L. Ecological risk assessment in a large river-reservoir: 8. Experimental study of the effects of polychlorinated biphenyls on reproductive success in mink. Environ. Toxicol. Chem. 1999, 18 (4), 649-654.
24. Nims Raymond, W.; Lubet Ronald, A. Induction of cytochrome P-450 in the Norway rat, Rattus norvegicus, following exposure to potential environmental contaminants. J. Toxicol. Environ. Health 1995, 46 (3), 271-292.
25. Nerurkar, P. V.; Park, S. S.; Thomas, P. E.; Nims, R. W.; Lubet, R. A. Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem. Pharmacol. 1993, 46 (5), 933-943.
26. Quails, C. W.; Lubet, R. A.; Lochmiller, R. L.; Elangbam, C. S.; Lish, J. W.; Nims, R. W. Cytochrome P450 induction in feral Cricetid rodents: a review of field and laboratory investigations. Comp. Biochem. Physiol., Part C: Pharmacol., Toxicol. Endocrinol. 1998, 121 (1-3), 55-63.
27. Jones, C. R.; Lubet, R. A.; Henneman, J. R.; Nims, R. W. Dose-response relationships for cytochrome P450 induction by phenobarbital in the cotton rat (Sigmodon hispidus). Comp. Biochem. Physiol., Part C: Pharmacol., Toxicol. Endocrinol. 1998, 121 (1-3), 197-203.
28. Lewis, D. F. V.; Lake, B. G.; Parke, D. V. Molecular orbital-generated QSARs in a homologous series of alkoxyresorufins and studies of their interactive docking with P450s. Xenobiotica 1995, 25 (12), 1355-1369.
29. Kaminsky, L. S.; Kennedy, M. W.; Adams, S. M.; Guengerich, F. P. Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P-450. Biochemistry 1981, 20, 7379-7384.
30. Mills, R. A.; Millis, C. D.; Dannan, G. A.; Guengerich, F. P.; Aust, S. D. Studies on the structure-activity relationships for the metabolism of polybrominated biphenyls by rat liver microsomes. Toxicol. Appl. Pharmacol. 1985, 78 (1), 96-104.
31. Hendriks, A. J.; Ma, W. C.; Brouns, J. J.; De, R. D. E. M.; Gast, R. Modelling and monitoring organochlorine and heavy metal accumulation in soils, earthworms and shrews in rhine-delta floodplains. Arch. Environ. Contain. Toxicol. 1995, 29 (1), 115-127.
32. Blaich, G.; Goettlicher, M.; Cikryt, P.; Metzler, M. Induction of P-450 isoenzyme activities in Syrian golden hamster liver compared to rat liver as probed by the rate of 7-alkoxyresorufin-O-dealkylation. Chem. Biol. Interact. 1988, 67 (1-2), 129-138.
33. Mahnke, A.; Strotkamp, D.; Roos, P. H.; Hanstein, W. G.; Chabot, G. G.; Nef, P. Expression and inducibility of cytochrome P450 3A9 (CYP3A9) and other members of the CYP3A subfamily in rat liver. Arch. Biochem. Biophys. 1997, 337 (1), 62-68.
34. Van den Brink, N. W.; Lee-de Groot, M. B. E.; De Bie, P. A. F.; Bosveld, A. T. C. Enzyme markers in frogs (Rana spp.) for monitoring risk of aquatic pollution. Aquat. Ecosyst. Health Manage. 2003, 6 (4), 441-448.
35. Van den Brink, N. W.; Van Franeker, J. A.; De Ruiter-Dijkman, E. M. Fluctuating concentrations of organochlorine pollutants during a breeding season in two Antarctic seabirds: Adelie penguin and southern fulmar. Environ. Toxicol. Chem. 1998, 17 (4), 702-709.