Combined use of tacrolimus and sirolimus in de novo renal transplant patients: Current data

Transplantation Proceedings

Volumn 37, Issue 6, 2005, Pages 2813-2816

  Ribes, D ^a   Kamar, N ^a   Esposito, L ^a   Rostaing, L ^a,b  

^a TOULOUSE UNIVERSITY HOSPITAL   (France)

^b CHU RANGUEIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS;

ACUTE GRAFT REJECTION; ACUTE KIDNEY TUBULE NECROSIS; ANEMIA; CONFERENCE PAPER; DIARRHEA; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; PRIORITY JOURNAL; WOUND HEALING; WOUND HEALING IMPAIRMENT;

EID: 25144463601     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2005.05.029     Document Type: Article

References (16)

1. M.E. Cardenas, D. Zhu, J. Heitman Molecular mechanisms of immunosuppression by cyclosporine, FK 506, and rapamycin Curr Opin Nephrol Hyperten 6 1995 472 477
2. H. Podder, S.M. Stepkowski, K.L. Napoli Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations J Am Soc Nephrol 5 2001 1059 1071
3. R. Oberbauer, H. Kreis, R.W. Johnson Rapamune Maintenance Regimen Study Group Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients 2-year results of the Rapamune Maintenance Regimen Study Group Transplantation 76 2003 364
4. A. Mota, M. Arias, E.I. Taskinen Rapamune Maintenance Regimen Trial Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years Am J Transplant 4 2004 953
5. S. Vitko, R. Margreiter, W. Weimar Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients Transplantation 78 2004 1532
6. S. Vitko, H. Tedesco, J. Eris Everolimus with optimized cyclosporine dosing in renal transplant recipients 6-month safety and efficacy results of two randomized study Am J Transplant 4 2004 626
7. N.A. Undre Pharmacokinetics of tacrolimus-based combination therapies Nephrol Dial Transplant 18 Suppl 1 2003 i12
8. J.P. Van Hoff, J.P. Squifflet, Z. Wlodarczyk A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients Transplantation 75 2003 1934
9. T. Gonwa, R. Mendez, H.C. Yang Prograf Study Group Randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation results at 6 month Transplantation 75 2003 1213
10. G. Cianco, G.W. Burke, J.J. Gaynor A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (NEORAL) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year Transplantation 77 2004 244
11. G. Cianco, G.W. Burke, J.J. Gaynor A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year Transplantation 77 2004 252
12. th International Congress of the Transplantation Society, 5-10 Sept 2004, Vienna. Abstract book, p 112 (O286)
13. J.F. Valente, D. Hricik, K. Weigel Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation Am J Transplant 3 2003 1128
14. C. Troppman, J.L. Pierce, M.M. Gandkhi Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation a matched-pair pilot study Transplantation 76 2003 426
15. Y. Akselband, M.W. Harding, P.A. Nelson Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts Transplant Proc 23 1991 2833
16. R. Humar, F.N. Kiefer, H. Berns Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependant signaling FASEB J 16 2002 771