Cerebrospinal fluid levels of neurofilament light in chronic experimental autoimmune encephalomyelitis

Brain Research Bulletin

Volumn 67, Issue 4, 2005, Pages 264-268

  Norgren, N ^a   Edelstam, A ^a   Stigbrand, T ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Autoimmune; Cerebrospinal fluid; Encephalomyelitis

Indexed keywords

MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE COURSE; FEMALE; IMMUNIZATION; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; MEASUREMENT; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; BLOTTING, WESTERN; CHRONIC DISEASE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; MYELIN-ASSOCIATED GLYCOPROTEIN; NEUROFILAMENT PROTEINS; RATS; SPINAL CORD; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 25144444459     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.06.031     Document Type: Article

References (24)

1. M. Adelmann, J. Wood, I. Benzel, P. Fiori, H. Lassmann, J.M. Matthieu, M.V. Gardinier, K. Dornmair, and C. Linington The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat J. Neuroimmunol. 63 1995 17 27
2. A.R. Consiglio, and A.B. Lucion Technique for collecting cerebrospinal fluid in the cisterna magna of non-anesthetized rats Brain Res. Brain Res. Protoc. 5 2000 109 114
3. I. Dahlman, E. Wallstrom, R. Weissert, M. Storch, B. Kornek, L. Jacobsson, C. Linington, H. Luthman, H. Lassmann, and T. Olsson Linkage analysis of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the rat identifies a locus controlling demyelination on chromosome 18 Hum. Mol. Genet. 8 1999 2183 2190
4. C. Funchal, L.M. de Almeida, S. Oliveira Loureiro, L. Vivian, P. de Lima Pelaez, F. Dall Bello Pessutto, A.M. Rosa, M. Wajner, and R. Pessoa Pureur In vitro phosphorylation of cytoskeletal proteins from cerebral cortex of rats Brain Res. Brain Res. Protoc. 11 2003 111 118
5. T.G. Johns, N. Kerlero de Rosbo, K.K. Menon, S. Abo, M.F. Gonzales, and C.C. Bernard Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis J. Immunol. 154 1995 5536 5541
6. J.P. Julien, and W.E. Mushynski Neurofilaments in health and disease Prog. Nucleic Acid Res. Mol. Biol. 61 1998 1 23
7. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
8. R.C. Lariviere, and J.P. Julien Functions of intermediate filaments in neuronal development and disease J. Neurobiol. 58 2004 131 148
9. H. Link, and B.G. Xiao Rat models as tool to develop new immunotherapies Immunol. Rev. 184 2001 117 128
10. J.N. Lycke, J.E. Karlsson, O. Andersen, and L.E. Rosengren Neurofilament protein in cerebrospinal fluid: a potential marker of activity in multiple sclerosis J. Neurol. Neurosurg. Psychiatry 64 1998 402 404
11. C. Malmeström, S. Haghighi, L. Rosengren, O. Andersen, and J. Lycke Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS Neurology 61 2003 1720 1725
12. N. Norgren, J.E. Karlsson, L. Rosengren, and T. Stigbrand Monoclonal antibodies selective for low molecular weight neurofilaments Hybrid. Hybridomics 21 2002 53 59
13. N. Norgren, L. Rosengren, and T. Stigbrand Elevated neurofilament levels in neurological diseases Brain Res. 987 2003 25 31
14. N. Norgren, P. Sundström, A. Svenningsson, L. Rosengren, T. Stigbrand, and M. Gunnarsson Neurofilament and glial fibrillary acidic protein in multiple sclerosis Neurology 63 2004 1586 1590
15. K. Nylen, J.E. Karlsson, C. Blomstrand, A. Tarkowski, E. Trysberg, and L.E. Rosengren Cerebrospinal fluid neurofilament and glial fibrillary acidic protein in patients with cerebral vasculitis J. Neurosci. Res. 67 2002 844 851
16. A. Petzold, G. Keir, A.J. Green, G. Giovannoni, and E.J. Thompson A specific ELISA for measuring neurofilament heavy chain phosphoforms J. Immunol. Methods 278 2003 179 190
17. A. Petzold, M.J. Eikelenboom, G. Keir, D. Grant, R.H. Lazeron, C.H. Polman, B.M. Uitdehaag, E.J. Thompson, and G. Giovannoni Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study J. Neurol. Neurosurg. Psychiatry 76 2005 206 211
18. T.M. Rivers, D.H. Sprunt, and G.P. Berry Observations on attempts to produce acute disseminated encephalomyelitis in monkeys J. Exp. Med. 58 1933 39 53
19. L.E. Rosengren, J.E. Karlsson, J.O. Karlsson, L.I. Persson, and C. Wikkelso Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF J. Neurochem. 67 1996 2013 2018
20. L. Steinman Multiple sclerosis: a two-stage disease Nat. Immunol. 2 2001 762 764
21. M.K. Storch, A. Stefferl, U. Brehm, R. Weissert, E. Wallstrom, M. Kerschensteiner, T. Olsson, C. Linington, and H. Lassmann Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology Brain Pathol. 8 1998 681 694
22. H. Towbin, T. Staehelin, and J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl. Acad. Sci. U.S.A. 76 1979 4350 4354
23. I. Tsunoda, and R.S. Fujinami Two models for multiple sclerosis: experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus J. Neuropathol. Exp. Neurol. 55 1996 673 686
24. J.R. Wujek, C. Bjartmar, E. Richer, R.M. Ransohoff, M. Yu, V.K. Tuohy, and B.D. Trapp Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis J. Neuropathol. Exp. Neurol. 61 2002 23 32