-
2
-
-
0033003074
-
Molecular pathogenesis of chronic myeloid leukemia: Implications for new therapeutic strategies
-
M. Warmuth, S. Danhauser-Riedl, and M. Hallek Molecular pathogenesis of chronic myeloid leukemia: implications for new therapeutic strategies Ann. Hematol. 78 1999 49 64
-
(1999)
Ann. Hematol.
, vol.78
, pp. 49-64
-
-
Warmuth, M.1
Danhauser-Riedl, S.2
Hallek, M.3
-
3
-
-
16844366670
-
ABL oncogenes and phosphoinositide 3-kinase: Mechanism of activation and downstream effectors
-
M.G. Kharas, and D.A. Fruman ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors Cancer Res. 65 2005 2047 2053
-
(2005)
Cancer Res.
, vol.65
, pp. 2047-2053
-
-
Kharas, M.G.1
Fruman, D.A.2
-
4
-
-
2942648711
-
Signal transduction pathways in Bcr-Abl transformed cells
-
R. Arlinghaus, and T. Sun Signal transduction pathways in Bcr-Abl transformed cells Cancer Treat Res. 119 2004 239 270
-
(2004)
Cancer Treat Res.
, vol.119
, pp. 239-270
-
-
Arlinghaus, R.1
Sun, T.2
-
5
-
-
0032556921
-
BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner
-
N. Cambier, R. Chopra, A. Strasser, D. Metcalf, and A.G. Elefanty BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner Oncogene 16 1998 335 348
-
(1998)
Oncogene
, vol.16
, pp. 335-348
-
-
Cambier, N.1
Chopra, R.2
Strasser, A.3
Metcalf, D.4
Elefanty, A.G.5
-
7
-
-
0028147448
-
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway
-
L. Puil, J. Liu, G. Gish, G. Mbamalu, D. Bowtell, P.G. Pelicci, R. Arlinghaus, and T. Pawson Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway EMBO J. 13 1994 764 773
-
(1994)
EMBO J.
, vol.13
, pp. 764-773
-
-
Puil, L.1
Liu, J.2
Gish, G.3
Mbamalu, G.4
Bowtell, D.5
Pelicci, P.G.6
Arlinghaus, R.7
Pawson, T.8
-
8
-
-
0035803494
-
Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: A novel regulatory mechanism for tyrosine kinase signaling
-
S. Li, A.D. Couvillon, B.B. Brasher, and R.A. Van Etten Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling EMBO J. 20 2001 6793 6804
-
(2001)
EMBO J.
, vol.20
, pp. 6793-6804
-
-
Li, S.1
Couvillon, A.D.2
Brasher, B.B.3
Van Etten, R.A.4
-
9
-
-
0028980342
-
Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis
-
D. Cortez, L. Kadlec, and A.M. Pendergast Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis Mol. Cell. Biol. 15 1995 5531 5541
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5531-5541
-
-
Cortez, D.1
Kadlec, L.2
Pendergast, A.M.3
-
10
-
-
0034665903
-
CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs
-
G. Fang, C.N. Kim, C.L. Perkins, N. Ramadevi, E. Winton, S. Wittmann, and K.N. Bhalla CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs Blood 96 2000 2246 2253
-
(2000)
Blood
, vol.96
, pp. 2246-2253
-
-
Fang, G.1
Kim, C.N.2
Perkins, C.L.3
Ramadevi, N.4
Winton, E.5
Wittmann, S.6
Bhalla, K.N.7
-
11
-
-
7644244868
-
FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism
-
S. Fernandez de Mattos, A. Essafi, I. Soeiro, A.M. Pietersen, K.U. Birkenkamp, C.S. Edwards, A. Martino, B.H. Nelson, J.M. Francis, M.C. Jones, J.J. Brosens, P.J. Coffer, and E.W. Lam FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism Mol. Cell. Biol. 24 2004 10058 10071
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10058-10071
-
-
Fernandez De Mattos, S.1
Essafi, A.2
Soeiro, I.3
Pietersen, A.M.4
Birkenkamp, K.U.5
Edwards, C.S.6
Martino, A.7
Nelson, B.H.8
Francis, J.M.9
Jones, M.C.10
Brosens, J.J.11
Coffer, P.J.12
Lam, E.W.13
-
12
-
-
10744220576
-
BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression
-
Y. Parada, L. Banerji, J. Glassford, N.C. Lea, M. Collado, C. Rivas, J.L. Lewis, M.Y. Gordon, N.S. Thomas, and E.W. Lam BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression J. Biol. Chem. 276 2001 23572 23580
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23572-23580
-
-
Parada, Y.1
Banerji, L.2
Glassford, J.3
Lea, N.C.4
Collado, M.5
Rivas, C.6
Lewis, J.L.7
Gordon, M.Y.8
Thomas, N.S.9
Lam, E.W.10
-
13
-
-
0037330625
-
Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
-
A.L. Gartel, and K. Shchors Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes Exp. Cell Res. 283 2003 17 21
-
(2003)
Exp. Cell Res.
, vol.283
, pp. 17-21
-
-
Gartel, A.L.1
Shchors, K.2
-
14
-
-
0037737498
-
Switching from life to death: The Miz-ing link between Myc and p53
-
K.H. Vousden Switching from life to death: the Miz-ing link between Myc and p53 Cancer Cell 2 2002 351 352
-
(2002)
Cancer Cell
, vol.2
, pp. 351-352
-
-
Vousden, K.H.1
-
15
-
-
0037464449
-
Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli
-
G. Brumatti, R. Weinlich, C.F. Chehab, M. Yon, and G.P. Amarante-Mendes Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli FEBS Lett. 541 2003 57 63
-
(2003)
FEBS Lett.
, vol.541
, pp. 57-63
-
-
Brumatti, G.1
Weinlich, R.2
Chehab, C.F.3
Yon, M.4
Amarante-Mendes, G.P.5
-
16
-
-
0034665780
-
Bcr/Abl activates transcription of the Bcl-X gene through STAT5
-
F. Gesbert, and J.D. Griffin Bcr/Abl activates transcription of the Bcl-X gene through STAT5 Blood 96 2000 2269 2276
-
(2000)
Blood
, vol.96
, pp. 2269-2276
-
-
Gesbert, F.1
Griffin, J.D.2
-
17
-
-
0032546266
-
Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: Protection is correlated with up regulation of Bcl-xL
-
G.P. Amarante-Mendes, A.J. McGahon, W.K. Nishioka, D.E. Afar, O.N. Witte, and D.R. Green Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL Oncogene 16 1998 1383 1390
-
(1998)
Oncogene
, vol.16
, pp. 1383-1390
-
-
Amarante-Mendes, G.P.1
McGahon, A.J.2
Nishioka, W.K.3
Afar, D.E.4
Witte, O.N.5
Green, D.R.6
-
18
-
-
0037174860
-
An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K
-
H.C. Chen, W.C. Lin, Y.G. Tsay, S.C. Lee, and C.J. Chang An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K J. Biol. Chem. 277 2002 40403 40409
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40403-40409
-
-
Chen, H.C.1
Lin, W.C.2
Tsay, Y.G.3
Lee, S.C.4
Chang, C.J.5
-
19
-
-
0141703274
-
Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase
-
K.N. Mahajan, and B.S. Mitchell Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase Proc. Natl. Acad. Sci. USA 100 2003 10746 10751
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10746-10751
-
-
Mahajan, K.N.1
Mitchell, B.S.2
-
21
-
-
0347481379
-
Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling
-
G. Fusaro, P. Dasgupta, S. Rastogi, B. Joshi, and S. Chellappan Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling J. Biol. Chem. 278 2003 47853 47861
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47853-47861
-
-
Fusaro, G.1
Dasgupta, P.2
Rastogi, S.3
Joshi, B.4
Chellappan, S.5
-
22
-
-
0034733508
-
Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase
-
T. Yokogawa, N. Shimada, N. Takeuchi, L. Benkowski, T. Suzuki, A. Omori, T. Ueda, K. Nishikawa, L.L. Spremulli, and K. Watanabe Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase J. Biol. Chem. 275 2000 19913 19920
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19913-19920
-
-
Yokogawa, T.1
Shimada, N.2
Takeuchi, N.3
Benkowski, L.4
Suzuki, T.5
Omori, A.6
Ueda, T.7
Nishikawa, K.8
Spremulli, L.L.9
Watanabe, K.10
-
23
-
-
0033601303
-
Cytosolic chaperonin is up-regulated during cell growth. Preferential expression and binding to tubulin at G(1)/S transition through early S phase
-
S. Yokota, H. Yanagi, T. Yura, and H. Kubota Cytosolic chaperonin is up-regulated during cell growth. Preferential expression and binding to tubulin at G(1)/S transition through early S phase J. Biol. Chem. 274 1999 37070 37078
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37070-37078
-
-
Yokota, S.1
Yanagi, H.2
Yura, T.3
Kubota, H.4
-
24
-
-
21144450049
-
ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle
-
S.E. Babbitt, A. Kiss, A.E. Deffenbaugh, Y.H. Chang, E. Bailly, H. Erdjument-Bromage, P. Tempst, T. Buranda, L.A. Sklar, J. Baumler, E. Gogol, and D. Skowyra ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle Cell 121 2005 553 565
-
(2005)
Cell
, vol.121
, pp. 553-565
-
-
Babbitt, S.E.1
Kiss, A.2
Deffenbaugh, A.E.3
Chang, Y.H.4
Bailly, E.5
Erdjument-Bromage, H.6
Tempst, P.7
Buranda, T.8
Sklar, L.A.9
Baumler, J.10
Gogol, E.11
Skowyra, D.12
-
25
-
-
2942620845
-
Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome
-
M.K. London, B.I. Keck, P.C. Ramos, and R.J. Dohmen Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome FEBS Lett. 567 2004 259 264
-
(2004)
FEBS Lett.
, vol.567
, pp. 259-264
-
-
London, M.K.1
Keck, B.I.2
Ramos, P.C.3
Dohmen, R.J.4
-
26
-
-
0032146759
-
ERp28, a human endoplasmic-reticulum-lumenal protein is a member of the protein, disulfide isomerase family but lacks a CXXC thioredoxin-box motif
-
D.M. Ferrari, P. Nguyen Van, H.D. Kratzin, and H.D. Soling ERp28, a human endoplasmic-reticulum-lumenal protein is a member of the protein, disulfide isomerase family but lacks a CXXC thioredoxin-box motif Eur. J. Biochem. 255 1998 570 579
-
(1998)
Eur. J. Biochem.
, vol.255
, pp. 570-579
-
-
Ferrari, D.M.1
Nguyen Van, P.2
Kratzin, H.D.3
Soling, H.D.4
-
27
-
-
10344236050
-
The acidic C-terminal domain stabilizes the chaperone function of protein disulfide isomerase
-
R. Tian, S.J. Li, D.L. Wang, Z. Zhao, Y. Liu, and R.Q. He The acidic C-terminal domain stabilizes the chaperone function of protein disulfide isomerase J. Biol. Chem. 279 2004 48830 48835
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48830-48835
-
-
Tian, R.1
Li, S.J.2
Wang, D.L.3
Zhao, Z.4
Liu, Y.5
He, R.Q.6
-
28
-
-
2542451939
-
S-Adenosylhomocysteine hydrolase as a target for intracellular adenosine action
-
D. Kloor, and H. Osswald S-Adenosylhomocysteine hydrolase as a target for intracellular adenosine action Trends Pharmacol. Sci. 25 2004 294 297
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 294-297
-
-
Kloor, D.1
Osswald, H.2
-
29
-
-
0032549664
-
Crystal structure of human recombinant ornithine aminotransferase
-
B.W. Shen, M. Hennig, E. Hohenester, J.N. Jansonius, and T. Schirmer Crystal structure of human recombinant ornithine aminotransferase J. Mol. Biol. 277 1998 81 102
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 81-102
-
-
Shen, B.W.1
Hennig, M.2
Hohenester, E.3
Jansonius, J.N.4
Schirmer, T.5
-
30
-
-
2142695445
-
Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells
-
T. Kawano, J. Horiguchi-Yamada, S. Saito, S. Iwase, Y. Furukawa, Y. Kano, and H. Yamada Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells Leuk. Res. 28 2004 623 629
-
(2004)
Leuk. Res.
, vol.28
, pp. 623-629
-
-
Kawano, T.1
Horiguchi-Yamada, J.2
Saito, S.3
Iwase, S.4
Furukawa, Y.5
Kano, Y.6
Yamada, H.7
-
31
-
-
25144471855
-
Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells
-
K. Kuzelova, D. Grebenova, I. Marinov, and Z. Hrkal Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells J. Cell Biochem. 95 2005 268 280
-
(2005)
J. Cell Biochem.
, vol.95
, pp. 268-280
-
-
Kuzelova, K.1
Grebenova, D.2
Marinov, I.3
Hrkal, Z.4
-
32
-
-
0030893763
-
Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells
-
M. Canelles, M.D. Delgado, K.M. Hyland, A. Lerga, C. Richard, C.V. Dang, and J. Leon Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells Oncogene 14 1997 1315 1327
-
(1997)
Oncogene
, vol.14
, pp. 1315-1327
-
-
Canelles, M.1
Delgado, M.D.2
Hyland, K.M.3
Lerga, A.4
Richard, C.5
Dang, C.V.6
Leon, J.7
-
33
-
-
0034065822
-
Ubiquitin-mediated proteolysis: Biological regulation via destruction
-
A. Ciechanover, A. Orian, and A.L. Schwartz Ubiquitin-mediated proteolysis: biological regulation via destruction Bioessays 22 2000 442 451
-
(2000)
Bioessays
, vol.22
, pp. 442-451
-
-
Ciechanover, A.1
Orian, A.2
Schwartz, A.L.3
-
34
-
-
0037834898
-
Ubiquitin-independent proteolytic functions of the proteasome
-
M. Orlowski, and S. Wilk Ubiquitin-independent proteolytic functions of the proteasome Arch. Biochem. Biophys. 415 2003 1 5
-
(2003)
Arch. Biochem. Biophys.
, vol.415
, pp. 1-5
-
-
Orlowski, M.1
Wilk, S.2
-
35
-
-
17744412856
-
The 26S proteasome system in the signaling pathways of TGF-beta superfamily
-
T. Wang The 26S proteasome system in the signaling pathways of TGF-beta superfamily Front Biosci. 8 2003 1109 1127
-
(2003)
Front Biosci.
, vol.8
, pp. 1109-1127
-
-
Wang, T.1
-
36
-
-
14844333094
-
Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: Identification of the Rho pathway as a target of BCR/ABL
-
R.D. Unwin, D.W. Sternberg, Y. Lu, A. Pierce, D.G. Gilliland, and A.D. Whetton Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL J. Biol. Chem. 280 2005 6316 6326
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6316-6326
-
-
Unwin, R.D.1
Sternberg, D.W.2
Lu, Y.3
Pierce, A.4
Gilliland, D.G.5
Whetton, A.D.6
-
37
-
-
3042626249
-
Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: Implications for adjuvant use of kinase-inhibitory drugs
-
Y.P. Lim, C.Y. Wong, L.L. Ooi, B.J. Druker, and R.J. Epstein Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs Clin. Cancer Res. 10 2004 3980 3987
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3980-3987
-
-
Lim, Y.P.1
Wong, C.Y.2
Ooi, L.L.3
Druker, B.J.4
Epstein, R.J.5
-
38
-
-
1942471909
-
Protein disulfide isomerase suppresses the transcriptional activity of NF-kappaB
-
T. Higuchi, Y. Watanabe, and I. Waga Protein disulfide isomerase suppresses the transcriptional activity of NF-kappaB Biochem. Biophys. Res. Commun. 318 2004 46 52
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 46-52
-
-
Higuchi, T.1
Watanabe, Y.2
Waga, I.3
-
39
-
-
8444243363
-
Targeting Rab GTPases to distinct membrane compartments
-
S. Pfeffer, and D. Aivazian Targeting Rab GTPases to distinct membrane compartments Nat. Rev. Mol. Cell Biol. 5 2004 886 896
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 886-896
-
-
Pfeffer, S.1
Aivazian, D.2
-
40
-
-
3042839349
-
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase
-
C. DerMardirossian, A. Schnelzer, and G.M. Bokoch Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase Mol. Cell 15 2004 117 127
-
(2004)
Mol. Cell
, vol.15
, pp. 117-127
-
-
Dermardirossian, C.1
Schnelzer, A.2
Bokoch, G.M.3
|