Protective effects of γ-aminobutyric acid in rats with streptozotocin-induced diabetes

Journal of Nutritional Science and Vitaminology

Volumn 51, Issue 4, 2005, Pages 278-282

  Nakagawa, Takako ^a   Yokozawa, Takako ^a   Kim, Hyun Ju ^a   Shibahara, Naotoshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Diabetes; Glucose; Glycosylated protein; Thiobarbituric acid reactive substance; aminobutyric acid

Indexed keywords

4 AMINOBUTYRIC ACID; GLUCOSE; GLYCOSYLATED PROTEIN; STREPTOZOCIN; THIOBARBITURIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERTROPHY; KIDNEY MASS; LIVER WEIGHT; MALE; NONHUMAN; RAT; WEIGHT GAIN;

ANIMALIA; RATTUS NORVEGICUS;

EID: 25144432864     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.51.278     Document Type: Article

References (34)

1. The Diabetes Control and Complication Trial Research Group. 1993. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986.
2. Baynes JW. 1991. Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412.
3. Giugliano D, Ceriello A, Paolisso G. 1996. Oxidative stress and diabetic vascular complications. Diabetes Care 19: 257-267.
4. Ha H, Kim KH. 1995. Role of oxidative stress in the development of diabetic nephropathy. Kidney Int 51: s18-s21.
5. Kakimoto M, Inoguchi T, Sonta T, Yu HY, Imamura M, Etoh T, Hashimoto T, Nawata H. 2002. Accumulation of 8-hydroxy-2′-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. Diabetes 51: 1588-1595.
6. Erdo SL. 1985. Peripheral GABAergic mechanisms. Trends Pharmacol Sci 6: 205-208.
7. Fagg GE, Foster AC. 1983. Amino acid neurotransmitters and their pathways in the mammalian central nervous system. Neuroscience 9: 701-719.
8. Antonaccio MJ, Kerwin L, Taylor DG. 1978. Reduction in blood pressure, heart rate and renal sympathetic nerve discharge in cats after the central administration of muscimol, a GABA agonist. Neuropharmacology 17: 783-791.
9. Matheson GK, Freed E, Tunnicliff G. 1986. Novel GABA analogues as hypotensive agents. Neuropharmacology 25: 1191-1195.
10. Loscher W. 1982. Cardiovascular effects of GABA, GABA-aminotransferase inhibitors and valproic acid following systemic administration in rats, cats and dogs: pharmacological approach to localize the site of action. Arch Int Pharmacodyn Ther 257: 32-58.
11. Ishikawa K, Saito S. 1978. Effect of intraventricular γ-aminobutyric acid (GABA) on discrimination learning in rats. Psychopharmacology 56: 127-132.
12. Tsushida T, Murai T, Omori M, Okamoto J. 1987. Production of a new type tea containing a high level of γ-aminobutyric acid. Nippon Nogeikagaku Kaishi 61: 817-822 (in Japanese).
13. Saikusa T, Horino T, Mori Y. 1994. Accumulation of γ-aminobutyric acid (GABA) in the rice germ during water soaking. Biosci Biotechnol Biochem 58: 2291-2292.
14. Hayakawa K, Ueno Y, Kawamura S, Taniguchi R, Oda K. 1997. Production of γ-aminobutyric acid by lactic acid bacteria. Seibutsu Kougaku Kaishi 75: 239-244 (in Japanese).
15. Kono I, Himeno K. 2000. Changes in γ-aminobutyric acid content during beni-koji making. Biosci Biotechnol Biochem 64: 617-619.
16. 1c. FEBS Lett 71: 356-360.
17. Naito C, Yamanaka T. 1978. Atherosclerotic disorder and lipid peroxidation. Jpn J Geriatr 15: 187-191.
18. Johnson D, Lardy H. 1967. Isolation of liver and kidney mitochondria. Methods Enzymol X: 94-96.
19. Jung K, Pergande M. 1985. Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria. FEBS Lett 183: 167-169.
20. Mihara M, Uchiyama M. 1978. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86: 271-278.
21. Itzhaki RF, Gill DM. 1964. A micro-biuret method for estimating proteins. Anal Biochem 9: 401-410.
22. Okada T, Sugishita T, Murakami T, Murai H, Saikusa T, Horino T, Onoda A, Kajimoto O, Takahashi R, Takahashi T. 2000. Effect of the defatted rice germ enriched with GABA for sleeplessness, depression, autonomic disorder by oral administration. Nippon Shokuhin Kagaku Kogaku Kaishi 47: 596-603 (in Japanese).
23. Omori M, Yano T, Okamoto J, Tsushida T, Murai T, Higuchi M. 1987. Effect of anaerobically treated tea (gabaron tea) on blood pressure of spontaneously hypertensive rats. Nippon Nogeikagaku Kaishi 61: 1449-1451 (in Japanese).
24. Tsuji K, Ichikawa T, Tanabe N, Abe S, Tarui S, Nakagawa Y. 1992. Antihyper tensive activities of beni-koji extracts and γ-aminobutyric acid in spontaneously hypertensive rats. Jpn J Nutr Dietetics 50: 285-291.
25. Nakamura T, Matsubayashi T, Kamachi K, Hasegawa T, Ando Y, Omori M. 2000. γ-Aminobutyric acid (GABA)-rich Chlorella depresses the elevation of blood pressure in spontaneously hypertensive rats (SHR). Nippon Nogeikagaku Kaishi 74: 907-909 (in Japanese).
26. Bunn HF, Gabbay KH, Gallop PM. 1978. The glycosylation of hemoglobin: relevance to diabetes mellitus. Science 200: 21-27.
27. McFarland KF, Catalano EW, Day JF, Thorpe SR, Baynes JW. 1979. Nonenzymatic glucosylation of serum proteins in diabetes mellitus. Diabetes 28: 1011-1014.
28. Hunt JV, Bottoms MA, Mitchinson MJ. 1993. Oxidative alterations in the experimental glycation model of diabetes mellitus are due to protein-glucose adduct oxidation. Some fundamental differences in proposed mechanisms of glucose oxidation and oxidant production. Biochem J 291: 529-535.
29. Mullarkey CJ, Edelstein D, Brownlee M. 1990. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun 173: 932-939.
30. Loven D, Schedl H, Wilson H, Daabees TT, Stegink LD, Diekus M, Oberley L. 1986. Effect of insulin and oral glutathione on glutathione levels and superoxide dismutase activities in organs of rats with streptozocin-induced diabetes. Diabetes 35: 503-507.
31. Wohaieb SA, Godin DV. 1987. Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment. Diabetes 36: 1014-1018.
32. Sato Y, Hotta N, Sakamoto N, Matsuoka S, Ohishi N, Yagi K. 1979. Lipid peroxide level in plasma of diabetic patients. Biochem Med 21: 104-107.
33. 2 balance in the diabetic rat: influence of dietary vitamin E. Diabetes 31: 947-951.
34. Nourooz-Zadeh J, Rahimi A, Tajaddini-Sarmadi J, Tritschler H, Rosen P, Halliwell B, Betteridge DJ. 1997. Relationships between plasma measures of oxidative stress and metabolic control in NIDDM. Diabetologia 40: 647-653.