Mucin granules are in close contact with tubular elements of the endoplasmic reticulum

Journal of Histochemistry and Cytochemistry

Volumn 53, Issue 10, 2005, Pages 1305-1309

  Perez Vilar, Juan ^a   Ribeiro, Carla M Pedrosa ^a   Salmon, Wendy C ^b   Mabolo, Raean ^a   Boucher, Richard C ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Endoplasmic reticulum; FRAP; Goblet cell; Mucin granule; Mucins; Mucous cell; Organelles

Indexed keywords

MUCIN;

ARTICLE; CANCER CELL CULTURE; CELL GRANULE; CELL ORGANELLE; CELL TYPE; ENDOPLASMIC RETICULUM; GOBLET CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; ENDOSOMES; GOBLET CELLS; GOLGI APPARATUS; GREEN FLUORESCENT PROTEINS; HUMANS; LYSOSOMES; MUCINS; RECOMBINANT FUSION PROTEINS;

EID: 24944582117     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.5B6713.2005     Document Type: Article

References (12)

1. Gerasimenko OV, Gerasimenko JV, Rizzuto RR, Treiman M, Tepikin AV, Petersen OH (2002) The distribution of the endoplasmic reticulum in living pancreatic acinar cells. Cell Calcium 32:261-268
2. Lethem MI, Dowell ML, Van Scott M, Yankaskas JR, Egan T, Boucher RC, Davis CW (1993) Nucleotide regulation of goblet cells in human airway epithelial explants: normal exocytosis in cystic fibrosis. Am J Respir Cell Mol Biol 9:315-322
3. Nakamura N, Lowe M, Levine TP, Rabouille C, Warren G (1997) The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner. Cell 89:445-455
4. Neutra MR, Phillips TL, Phillips TE (1984) Regulation of intestinal goblet cells in situ, in mucosal explants and in the isolated epithelium. Ciba Found Symp 109:20-39
5. 2+. Nature 395:908-912
6. Perez-Vilar J, Olsen JC, Chua VI, Boucher RC (2005) pH-dependent intralummal organization of mucin granules in live human mucous/goblet cells. J Biol Chem 280:16868-16881
7. Phillips TE, Ramos R, Duncan SL (1995) HT29-18N2 differentiation in a protein-free medium. In Vitro Cell Dev Biol Anim 31:421-423
8. Puchelle E, Beorchia A, Menager M, Zahm JM, Ploton I (1991) Three-dimensional imaging of the mucus secretory process in the cryofixed frog respiratory epithelium. Biol Cell 72:159-166
9. 2', signals in human cystic fibrosis airway epithelia. J Biol Chem 280:10202-10209
10. 2+-independent' exocytosis in SPOC1 airway goblet cells. J Physiol 599:555-565
11. Shimomura S, Hisanmatsu K, Fujii Y, Ohno S (1996) An ultrastructural study of goblet cells in rat nasal mucosa as revealed by the quick-freezing method. J Anat 188:651-659
12. Specian RD, Oliver MG (1991) Functional biology of intestinal goblet cells. Am J Physiol 260:183-193