The phenylephrine blood pressure clamp in pharmacologic magnetic resonance imaging: Reduction of systemic confounds and improved detectability of drug-induced BOLD signal changes

Psychopharmacology

Volumn 180, Issue 4, 2005, Pages 774-780

  Kalisch, Raffael ^a,d   Delfino, Marina ^b   Murer, M Gustavo ^c   Auer, Dorothee P ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b Instituto de Investigaciones Farmacologicas   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d WELLCOME TRUST CENTRE FOR NEUROIMAGING   (United Kingdom)

Author keywords

6 OHDA; Apomorphine; Blood pressure; BOLD; Dopamine; Neuroimaging; Pharmacologic MRI; Phenylephrine; Rat; Receptor hypersensitivity

Indexed keywords

APOMORPHINE; DOPAMINE RECEPTOR STIMULATING AGENT; PHENYLEPHRINE; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ARTICLE; BLOOD OXYGENATION; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; BRAIN ELECTROPHYSIOLOGY; BRAIN PERFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; MALE; NEUROIMAGING; NEUROPHARMACOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; APOMORPHINE; BLOOD PRESSURE; BRAIN; DOPAMINE AGONISTS; DRUG ADMINISTRATION ROUTES; DRUG INTERACTIONS; FUNCTIONAL LATERALITY; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PHENYLEPHRINE; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS;

EID: 24944542333     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-005-2252-0     Document Type: Article

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