Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver

DNA Repair

Volumn 4, Issue 10, 2005, Pages 1099-1110

  Rusyn, Ivan ^a   Asakura, Shoji ^a,b   Li, Yutai ^a   Kosyk, Oksana ^a   Koc, Hasan ^a   Nakamura, Jun ^a   Upton, Patricia B ^a   Swenberg, James A ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b EISAI CO LTD   (Japan)

Author keywords

Brain; DNA damage; Ethylene; Ethylene oxide; Liver; Spleen

Indexed keywords

3 METHYLADENINE DEOXYRIBONUCLEIC ACID GLYCOSYLASE; 7 (2 HYDROXYETHYL)GUANINE; 8 OXOGUANINE DNA GLYCOSYLASE; ALDEHYDE; ALKYLGUANINE METHYLTRANSFERASE; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; ETHYLENE; ETHYLENE OXIDE; GLOBIN; METHYLTRANSFERASE; N7 (2 HYDROXYETHYL)VALINE; UNCLASSIFIED DRUG; VALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APURINIC SITE; APYRIMIDINIC SITE; ARTICLE; BRAIN TISSUE; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; EXPERIMENT; EXPOSURE; GENE EXPRESSION; INHALATION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPLEEN; TARGET ORGAN; TIME;

ADMINISTRATION, INHALATION; ANIMALS; APOPTOSIS; BRAIN; BRAIN CHEMISTRY; DNA; DNA ADDUCTS; DNA REPAIR; ETHYLENE OXIDE; ETHYLENES; GENE EXPRESSION; GUANINE; LIVER; MALE; RATS; RATS, INBRED F344; SPLEEN;

ANIMALIA;

EID: 24944529168     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2005.05.009     Document Type: Article

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