Intracapsular clear cell renal carcinoma: Ploidy status improves the prognostic value of the 2002 TNM classification

Journal of Urology

Volumn 174, Issue 4 I, 2005, Pages 1203-1207

  Minervini, Andrea ^a,c   Di Cristofano, Claudio ^b   Collecchi, Paola ^b   Salinitri, Giuseppe ^b   Selli, Cesare ^b   Bevilacqua, Generoso ^b   Minervini, Riccardo ^b   Cavazzana, Andrea ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Adenocarcinoma, clear cell; Carcinoma, renal cell; Cell proliferation; Kidney; Ploidies

Indexed keywords

DNA; KI 67 ANTIGEN;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER SURVIVAL; CELL CYCLE S PHASE; CLEAR CELL CARCINOMA; DNA CONTENT; EVALUATION; HIGH RISK POPULATION; HUMAN; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; METASTASIS; PLOIDY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PUBLICATION; VALIDATION PROCESS;

EID: 24944515386     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000173638.55569.79     Document Type: Article

References (20)

1. Fuhrman, S. A., Lasky, L. C. and Limas, C.: Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol, 6: 655, 1982
2. Gelb, A. B., Sudilovsky, D., Wu, C. D., Weiss, L. M. and Medeiros, L. J.: Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma. Cancer, 80: 1768, 1997
3. Minervini, A., Lilas, L., Minervini, R. and Selli, C.: Prognostic value of nuclear grading in patients with intracapsular (pT1-pT2) renal cell carcinoma. Long-term analysis in 213 patients. Cancer, 94: 2590, 2002
4. Cheville, J. C., Blute, M. L., Zincke, H., Lohse, C. M. and Weaver, A. L.: Stage pT1 conventional (clear cell) renal cell carcinoma: pathological features associated with cancer specific survival. J Urol, 166: 453, 2001
5. Sobin, L. H. and Wittekind, Ch.: International Union Against Cancer (UICC). TNM Classification of Malignant Tumours, 5th ed. New York: Wiley-Liss Publications, 1997
6. Sobin, L. and Wittekind, Ch.: International Union Against Cancer (UICC). TNM Classification of Malignant Tumours, 6th ed. New York: Wiley-Liss, 2002
7. Di Silverio, F., Casale, P., Colella, D., Andrea, L., Seccareccia, F. and Sciarra, A.: Independent value of tumor size and DNA ploidy for the prediction of disease progression in patients with organ-confined renal cell carcinoma. Cancer, 88: 835, 2000
8. Minervini, R., Minervini, A., Fontana, N., Traversi, C. and Cristofani, R.: Evaluation of the 1997 tumour, nodes and metastases classification of renal cell carcinoma: experience in 172 patients. BJU Int, 86: 199, 2000
9. Ficarra, V., Prayer-Galletti, T., Novara, G., Bratti, E., Zanolla, L., Dal Bianco, M. et al: Tumor-size breakpoint for prognostic stratification of localized renal cell carcinoma. Urology, 63: 235, 2004
10. Zisman, A., Pantuck, A. J., Chao, D., Dorey, F., Said, J. W., Gitlitz, B. J. et al: Reevaluation of the 1997 TNM classification for renal cell carcinoma: T1 and T2 cutoff point at 4.5 rather than 7 cm. better correlates with clinical outcome. J Urol, 166: 54, 2001
11. Abou-Rebyeh, H., Borgmann, V., Nagel, R. and Al-Abadi, H.: DNA ploidy is a valuable predictor for prognosis of patients with resected renal cell carcinoma. Cancer, 92: 2280, 2001
12. Cheville, J. C., Zincke, H., Lohse, C. M., Sebo, T. J., Riehle, D., Weaver, A. L. et al: pT1 clear cell renal cell carcinoma: a study of the association between MIB-1 proliferative activity and pathologic features and cancer specific survival. Cancer, 94: 2180, 2002
13. Cavazzana, A. O., Prayer-Galetti, T., Sangiorgio, A., Fassina, A. S., Panozzo, M., Zucchetta, P. et al: DNA content, nuclear grading and early tumor progression in renal cell cancer: a prospective study on frozen specimens. Eur Urol, 22:311, 1992
14. Storkel, S., Eble, J. N., Adlakha, K., Amin, M., Blute, M. L., Bostwick, D. G. et al: Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer, 80: 987, 1997
15. Moch, H., Gasser, T., Amin, M. B., Torhorst, J., Sauter, G. and Mihatsch, M. J.: Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma: a Swiss experience with 588 tumors. Cancer, 89: 604, 2000
16. Ficarra, V., Novara, G., Galfano, A., Novella, G., Schiavone, D. and Artibani, W.: Application of TNM, 2002 version, in localized renal cell carcinoma: is it able to predict different cancer-specific survival probability? Urology, 63: 1050, 2004
17. Ruiz-Cerda, J. L., Hernandez, M., Gomis, F., Vera, C. D., Kimler, B. F., O'Connor, J. E. et al: Value of deoxyribonucleic acid ploidy and nuclear morphometry for prediction of disease progression in renal cell carcinoma. J Urol, 155: 459, 1996
18. Shalev, M., Gdor, Y., Leventis, A., Radnay, J., Shapiro, H., Bernheim, J. et al: The prognostic value of DNA ploidy in small renal cell carcinoma. Pathol Res Pract, 197: 7, 2001
19. Currin, S. M., Lee, S. E. and Walther, P. J.: Flow cytometric assessment of deoxyribonucleic acid content in renal adenocarcinoma: does ploidy status enhance prognostic stratification over stage alone? J Urol, 143: 458, 1990
20. Ljungberg, B., Mehle, C., Stenling, R. and Roos, G.: Heterogeneity in renal cell carcinoma and its impact no prognosis - a flow cytometric study. Br J Cancer, 74: 123, 1996