Crystal structure of the antibiotic SY-1 (20-deoxy-salinomycin): Sodium 2-(6-[2-(5-ethyl-5-hydroxy-6-methyl-tetrahydro-pyran-2-yl)-2,10,12-trimethyl-1, 6,8-trioxa-dispiro[4.1.5.3]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxo- heptyl-5-methyl-tetrahydro-pyran-2-yl)-butyrate - Methanol solvate (1:0.69), C42H69NaO10 · 0.69CH3OH

Zeitschrift fur Kristallographie - New Crystal Structures

Volumn 218, Issue 4, 2003, Pages 575-577

  Paulus, E F ^a   Vertesy L ^b  

^a GOETHE UNIVERSITY   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 24944487512     PISSN: 14337266     EISSN: None     Source Type: Journal    
DOI: 10.1524/ncrs.2003.218.4.575     Document Type: Article

References (10)

1. Westley, J. W.; Blount, J. F.; Evans Jr., R. H.; Liu, Ch.-M.: C-17 Epimers of Deoxy-(O-8)-Salinomycin from Streptomyces albus (ATCC 21838). J. Antibiotics 30 (1977) 610-612.
2. Miyazaki, Y.; Shibata, A.; Tsuda, K.; Kinashi, H.; Otake, N.: Studies on the ionophorous antibiotics. Isolation, characterisation and structure of SY-1. Agric. Biol. Chem. 42 (1978), 2129.
3. Flack, H. D.; Bemardinelli, G.: Absolute structure and absolute configuration. Acta Crystallogr. A55 (1999) 908-915.
4. Hamilton, W. C.: Significance Tests on the Crystallographic R Factors. Acta Crystallogr. 18 (1965) 502-510.
5. Kinashi, H.; Otake, N.; Yonehara, H.; Sato, S.; Saito, Y.: Studies on the Ionophorous Antibiotics. I. The Crystal and Molecular Structure of Salino-mycin p-Iodophenacyl Ester. Acta Crystallogr. B31 (1975) 2411-2415.
6. Paulus, E. F.; Kurz, M.; Matter, H.; Vértesy, L.: Solid-State and Solution Structure of the Salinomycin-Sodium Complex: Stabilization of Different Conformers for an Ionophore in Different Environments. J. Am. Chem. Soc. 120 (1998) 8209-8221.
7. Paulus, E. F.; Vértesy, L.: The Antibiotic Salinomycin and another three Derivatives. Lecture MS2.6-6, 17th European Crystallographic Meeting, Lisboa 1997; Poster, Computing School on Practical Aspects of Charge Density Determination, Berlin 1997.
8. Sheldrick, G. M.: SHELXS-97. Program for the Solution of Crystal Structures. University of Göttingen, Germany 1997.
9. Sheldrick, G. M.: SHELXL-97. Program for the Refinement of Crystal Structures. University of Göttingen, Germany 1997.
10. Sheldrick, G. M.: SHELXTL-plus, Release 5.10. An Integrated System for Solving, Refining and Displaying Crystal Structures from Diffraction Data. Bruker Analytical Systems, Madison, Wisconsin, USA 1997.