Stimulation of cell surface plasminogen activation by membrane-bound melanotransferrin: A key phenomenon for cell invasion

Experimental Cell Research

Volumn 308, Issue 2, 2005, Pages 479-490

  Michaud Levesque, Jonathan ^a   Demeule, Michel ^a   Béliveau, Richard ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

Cell invasion; Cell migration; Cell motility; Melanotransferrin; Plasminogen; Plasminogen activation; Plasminogen receptor

Indexed keywords

CELL RECEPTOR; COMPLEMENTARY DNA; MELANOTRANSFERRIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY L235; PLASMINOGEN; TRANSFERRIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; MELANOMA SPECIFIC ANTIGENS; MELANOMA-SPECIFIC ANTIGENS; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR, UROKINASE RECEPTORS; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL STIMULATION; CELL SURFACE; CHO CELL; CONTROLLED STUDY; GENETIC TRANSFECTION; MELANOMA CELL; MEMBRANE BINDING; NONHUMAN; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; SOLUBILITY; ANIMAL; CANCER INVASION; CELL MEMBRANE; CELL MOTION; DRUG ANTAGONISM; GENETICS; HAMSTER; HUMAN; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; UPREGULATION;

ANIMALIA; CRICETULUS GRISEUS;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL MEMBRANE; CELL MOVEMENT; CHO CELLS; CRICETINAE; DNA, COMPLEMENTARY; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PLASMINOGEN; PLASMINOGEN ACTIVATORS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; TRANSFECTION; UP-REGULATION;

EID: 24944475751     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.05.004     Document Type: Article

References (45)

1. M. Ranson, N.M. Andronicos, M.J. O'Mullane, and M.S. Baker Increased plasminogen binding is associated with metastatic breast cancer cells: differential expression of plasminogen binding proteins Br. J. Cancer 77 1998 1586 1597
2. M. Ranson, and N.M. Andronicos Plasminogen binding and cancer: promises and pitfalls Front. Biosci. 8 2003 s294 s304
3. T. Herren, C. Swaisgood, and E.F. Plow Regulation of plasminogen receptors Front. Biosci. 8 2003 d1 d8
4. C. Longstaff Plasminogen activation on the cell surface Front. Biosci. 7 2002 d244 d255
5. S. Gately, P. Twardowski, M.S. Stack, D.L. Cundiff, D. Grella, F.J. Castellino, J. Enghild, H.C. Kwaan, F. Lee, R.A. Kramer, O. Volpert, N. Bouck, and G.A. Soff The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin Proc. Natl. Acad. Sci. U. S. A. 94 1997 10868 10872
6. Y. Gong, S.O. Kim, J. Felez, D.K. Grella, F.J. Castellino, and L.A. Miles Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface J. Biol. Chem. 276 2001 19078 19083
7. K.A. Hajjar, A.T. Jacovina, and J. Chacko An endothelial cell receptor for plasminogen/tissue plasminogen activator: I. Identity with annexin II J. Biol. Chem. 269 1994 21191 21197
8. K.A. Hajjar Cellular receptors in the regulation of plasmin generation Thromb. Haemostasis 74 1995 294 301
9. J.M. Rakic, C. Maillard, M. Jost, K. Bajou, V. Masson, L. Devy, V. Lambert, J.M. Foidart, and A. Noel Role of plasminogen activator-plasmin system in tumor angiogenesis Cell Mol. Life Sci. 60 2003 463 473
10. P.A. Andreasen, R. Egelund, and H.H. Petersen The plasminogen activation system in tumor growth, invasion, and metastasis Cell Mol. Life Sci. 57 2000 25 40
11. J.P. Brown, R.M. Hewick, I. Hellstrom, K.E. Hellstrom, R.F. Doolittle, and W.J. Dreyer Human melanoma-associated antigen p97 is structurally and functionally related to transferrin Nature 296 1982 171 173
12. J.P. Brown, R.G. Woodbury, C.E. Hart, I. Hellstrom, and K.E. Hellstrom Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues Proc. Natl. Acad. Sci. U. S. A. 78 1981 539 543
13. E.N. Baker, H.M. Baker, C.A. Smith, M.R. Stebbins, M. Kahn, K.E. Hellstrom, and I. Hellstrom Human melanotransferrin (p97) has only one functional iron-binding site FEBS Lett. 298 1992 215 218
14. T.M. Rose, G.D. Plowman, D.B. Teplow, W.J. Dreyer, K.E. Hellstrom, and J.P. Brown Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence Proc. Natl. Acad. Sci. U. S. A. 83 1986 1261 1265
15. R.G. Woodbury, J.P. Brown, S.M. Loop, K.E. Hellstrom, and I. Hellstrom Analysis of normal neoplastic human tissues for the tumor-associated protein p97 Int. J. Cancer 27 1981 145 149
16. R.G. Woodbury, J.P. Brown, M.Y. Yeh, I. Hellstrom, and K.E. Hellstrom Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms Proc. Natl. Acad. Sci. U. S. A. 77 1980 2183 2187
17. R. Sciot, R. de Vos, P. van Eyken, K. van der Steen, P. Moerman, and V.J. Desmet In situ localization of melanotransferrin (melanoma-associated antigen P97) in human liver. A light- and electronmicroscopic immunohistochemical study Liver 9 1989 110 119
18. R. Alemany, M.R. Vila, C. Franci, G. Egea, F.X. Real, and T.M. Thomson Glycosyl phosphatidylinositol membrane anchoring of melanotransferrin (p97): apical compartmentalization in intestinal epithelial cells J. Cell Sci. 104 Pt. 4 1993 1155 1162
19. S. Rothenberger, M.R. Food, R. Gabathuler, M.L. Kennard, T. Yamada, O. Yasuhara, P.L. McGeer, and W.A. Jefferies Coincident expression and distribution of melanotransferrin and transferrin receptor in human brain capillary endothelium Brain Res. 712 1996 117 121
20. T. Kawamoto, H. Pan, W. Yan, H. Ishida, E. Usui, R. Oda, K. Nakamasu, M. Noshiro, Y. Kawashima-Ohya, M. Fujii, H. Shintani, Y. Okada, and Y. Kato Expression of membrane-bound transferrin-like protein p97 on the cell surface of chondrocytes Eur. J. Biochem. 256 1998 503 509
21. M.R. Food, S. Rothenberger, R. Gabathuler, I.D. Haidl, G. Reid, and W.A. Jefferies Transport and expression in human melanomas of a transferrin-like glycosylphosphatidylinositol-anchored protein J. Biol. Chem. 269 1994 3034 3040
22. E. Sekyere, M.R. Food, and D.R. Richardson A second melanotransferrin gene (MTf2) and a novel protein isoform: explanation for the membrane-bound and soluble forms of melanotransferrin? FEBS Lett. 512 2002 350 352
23. K. Kriegerbeckova, and J. Kovar Role of melanotransferrin (p97) in non-transferrin iron uptake by HeLa and K562 cells Folia Biol. (Praha) 46 2000 77 81
24. D.R. Richardson The role of the membrane-bound tumour antigen, melanotransferrin (p97), in iron uptake by the human malignant melanoma cell Eur. J. Biochem. 267 2000 1290 1298
25. E. Sekyere, and D.R. Richardson The membrane-bound transferrin homologue melanotransferrin: roles other than iron transport? FEBS Lett. 483 2000 11 16
26. M.R. Food, E.O. Sekyere, and D.R. Richardson The soluble form of the membrane-bound transferrin homologue, melanotransferrin, inefficiently donates iron to cells via nonspecific internalization and degradation of the protein Eur. J. Biochem. 269 2002 4435 4445
27. M. Demeule, Y. Bertrand, J. Michaud-Levesque, J. Jodoin, Y. Rolland, R. Gabathuler, and R. Beliveau Regulation of plasminogen activation: a role for melanotransferrin (p97) in cell migration Blood 102 2003 1723 1731
28. J. Michaud-Levesque, Y. Rolland, M. Demeule, Y. Bertrand, and R. Béliveau Inhibition of endothelial cell movement and tubulogenesis by human recombinant soluble melanotransferrin: involvement of the u-PAR/LRP plasminolytic system Biochim. Biophys. Acta (BBA)-Mol. Cell Res. 1743 2005 243 253
29. J. Yang, J. Tiong, M. Kennard, and W.A. Jefferies Deletion of the GPI pre-anchor sequence in human p97-A general approach for generating the soluble form of GPI-linked proteins Protein Expr. Purif. 34 2004 28 48
30. M.L. Kennard, D.R. Richardson, R. Gabathuler, P. Ponka, and W.A. Jefferies A novel iron uptake mechanism mediated by GPI-anchored human p97 EMBO J. 14 1995 4178 4186
31. E.F. Plow, D.E. Freaney, J. Plescia, and L.A. Miles The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type J. Cell Biol. 103 1986 2411 2420
32. D.J. Falcone, W. Borth, K.M. Khan, and K.A. Hajjar Plasminogen-mediated matrix invasion and degradation by macrophages is dependent on surface expression of annexin II Blood 97 2001 777 784
33. K.A. Hajjar, P.C. Harpel, E.A. Jaffe, and R.L. Nachman Binding of plasminogen to cultured human endothelial cells J. Biol. Chem. 261 1986 11656 11662
34. K.A. Hajjar, and R.L. Nachman Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface J. Clin. Invest. 82 1988 1769 1778
35. J.P. Brown, K. Nishiyama, I. Hellstrom, and K.E. Hellstrom Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies J. Immunol. 127 1981 539 546
36. P.A. Andreasen, L. Kjoller, L. Christensen, and M.J. Duffy The urokinase-type plasminogen activator system in cancer metastasis: a review Int. J. Cancer 72 1997 1 22
37. L.A. Miles, C.M. Dahlberg, J. Plescia, J. Felez, K. Kato, and E.F. Plow Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor Biochemistry 30 1991 1682 1691
38. E.F. Plow, T. Herren, A. Redlitz, L.A. Miles, and J.L. Hoover-Plow The cell biology of the plasminogen system FASEB J. 9 1995 939 945
39. L.F. Lin, A. Houng, and G.L. Reed Epsilon amino caproic acid inhibits streptokinase-plasminogen activator complex formation and substrate binding through kringle-dependent mechanisms Biochemistry 39 2000 4740 4745
40. Z. Sun, Y.H. Chen, P. Wang, J. Zhang, V. Gurewich, P. Zhang, and J.N. Liu The blockage of the high-affinity lysine binding sites of plasminogen by EACA significantly inhibits prourokinase-induced plasminogen activation Biochim. Biophys. Acta 1596 2002 182 192
41. L.A. Liotta, P.S. Steeg, and W.G. Stetler-Stevenson Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation Cell 64 1991 327 336
42. K. Dano, P.A. Andreasen, J. Grondahl-Hansen, P. Kristensen, L.S. Nielsen, and L. Skriver Plasminogen activators, tissue degradation, and cancer Adv. Cancer Res. 44 1985 139 266
43. T. Tarui, M. Majumdar, L.A. Miles, W. Ruf, and Y. Takada Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin J. Biol. Chem. 277 2002 33564 33570
44. G. Brunner, K. Reimbold, A. Meissauer, V. Schirrmacher, and L.J. Erkell Sulfated glycosaminoglycans enhance tumor cell invasion in vitro by stimulating plasminogen activation Exp. Cell Res. 239 1998 301 310
45. A. Reijerkerk, E.E. Voest, and M.F. Gebbink No grip, no growth: the conceptual basis of excessive proteolysis in the treatment of cancer Eur. J. Cancer 36 2000 1695 1705