A molecular epidemiologic study of point mutations for pyrimethamine- sulfadoxine resistance of Plasmodium falciparum isolates from Lao PDR

Southeast Asian Journal of Tropical Medicine and Public Health

Volumn 36, Issue 3, 2005, Pages 602-604

  Toma, Hiromu ^a   Imada, Yumi ^a   Vannachone, Bouakham ^b   Miyagi, Mio ^a   Kobayashi, Jun ^c   Uechi, Gen Ichiro ^a   Pethuvang, Rattanasay ^b   Manivong, Khemphavanh ^d   Phompida, Samlane ^b   Sato, Yoshiya ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b Centre of Malariology   (Laos)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^d Malaria Station   (Laos)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 24944471389     PISSN: 01251562     EISSN: 26975718     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Biswas S, Escalante A, Chaiyaroj S, Angkasekwinai P, Lal AA. Prevalence of point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum isolates from India and Thailand: a molecular epidemiologic study. Trop Med Int Health 2000; 5: 737-43.
2. Giboda M, Pholsena K, Hongvathong B, Gutvirth J, Rubik I. Malariometric survey in Keoudom District, Lao PDR: sensitivity of Plasmodium falciparum to anti-malarials and automedication with chloroquine. Southeast Asian J Trop Med Public Health 1992; 23: 383-8.
3. Peterson DS, Walliker D, Wellems TE. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci USA 1988; 85: 9114-8.
4. Pholsena K. The malaria situation and anti-malaria program in Lao PDR. Southest Asian J Trop Med Public Health 1992; 23S: 39-42.
5. Pillai DR, Labbé AC, Vanisaveth V, et al. Plasmodium falciparum malaria in Lao PDR: chloroquine treatment outcome and predictive value of molecular markers. J Infect Dis 2001; 183: 789-95.
6. Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems TE. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Afirica. Am J Trop Med Hyg 1995; 52: 565-8.
7. Toma H, Kobayashi J, Imada Y, et al. Field application and evaluation of a rapid immunochromatographic test for detection of Plasmodium falciparum infection among the inhabitants of Lao PDR. Southest Asian J Trop Med Public Health 2003; 34: 43-7.
8. Triglia T, Menting JGT, Wilson C, Cowman AF. Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci USA 1997; 94: 13944-9.
9. Wang P, Brooks DR, Sims PFG, Hyde JE. Mutation-specific PCR system to detect sequence variation in dihydropteroate synthetase gene of Plasmodium falciparum. Mol Biochem Parasitol 1995; 71: 115-25.