Promoter analysis of cytolethal distending toxin genes (cdtA, B, and C) and effect of a luxS mutation on CDT production in Campylobacter jejuni

Microbiology and Immunology

Volumn 49, Issue 7, 2005, Pages 599-603

  Jeon, Byeonghwa ^a   Itoh, Kikuji ^a   Ryu, Sangryeol ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b Seoul National University   (South Korea)

Author keywords

Campylobacter jejuni; Cytolethal distending toxin; luxS

Indexed keywords

BACTERIAL TOXIN;

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CAMPYLOBACTER JEJUNI; CELL COUNT; CELL CYCLE G2 PHASE; CELL FREE SYSTEM; CISTRON; CONTROLLED STUDY; FLOW CYTOMETRY; GENE CONTROL; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; LUX S GENE; MITOSIS INHIBITION; MUTATIONAL ANALYSIS; NONHUMAN; OPERON; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WILD TYPE;

BACTERIA (MICROORGANISMS); CAMPYLOBACTER JEJUNI;

EID: 24744472240     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2005.tb03651.x     Document Type: Article

References (25)

1. Bang, D.D., Scheutz, F., Ahrens, P., Pedersen, K., Blom, J., and Madsen, M. 2001. Prevalence of cytolethal distending toxin (cdt) genes and CDT production in Campylobacter spp. isolated from Danish broilers. J. Med. Microbiol. 50: 1087-1094.
2. Bassler, B.L. 2002. Small talk: cell-to-cell communication in bacteria. Cell 109: 421-424.
3. Chen, X., Schauder, S., Potier, N., Van Dorsselaer, A., Pelczer, I., Bassler, B.L., and Hughson, F.M. 2002. Structural identification of a bacterial quorum-sensing signal containing boron. Nature 415: 545-549.
4. Cope, L.D., Lumbley, S., Latimer, J.L., Klesney-Tait, J., Stevens, M.K., Johnson, L.S., Purven, M., Jr., Munson, R.S., Lagergard, T., Radolf, J.D., and Hansen, E.J. 1997. A diffusible cytotoxin of Haemophilus ducreyi. Proc. Natl. Acad. Sci. U.S.A. 94: 4056-4061.
5. Elvers, K.T., and Park, S.F. 2002. Quorum sensing in Campylobacter jejuni: detection of a luxS encoded signalling molecule. Microbiology 148: 1475-1481.
6. Eyigor, A., Dawson, K.A., Langlois, B.E., and Pickett, C.L. 1999. Detection of cytolethal distending toxin activity and cdt genes in Campylobacter spp. isolated from chicken carcasses. Appl. Environ. Microbiol. 65: 1501-1505.
7. Hickey, T.E., McVeigh, A.L., Scott, D.A., Michielutti, R.E., Bixby, A., Carroll, S.A., Bourgeois, A.L., and Guerry, P. 2000. Campylobacter jejuni cytolethal distending toxin mediates release of interleukin-8 from intestinal epithelial cells. Infect. Immun. 68: 6535-6541.
8. Jeon, B., Itoh, K., Misawa, N., and Ryu, S. 2003. Effects of quorum sensing on flaA transcription and autoagglutination in Campylobacter jejuni. Microbiol. Immunol. 47: 833-839.
9. Johnson, W.M., and Lior, H. 1988. A new heat-labile cytolethal distending toxin (CLDT) produced by Campylobacter spp. Microb. Pathog. 4: 115-126.
10. Ketley, J.M. 1997. Pathogenesis of enteric infection by Campylobacter. Microbiology 143: 5-21.
11. Krishan, A. 1975. Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J. Cell Biol. 66: 188-193.
12. Lara-Tejero, M., and Galán, J.E. 2000. A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein. Science 290: 354-357.
13. Lara-Tejero, M., and Galán, J.E. 2001. CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect. Immun. 69: 4358-4365.
14. Okuda, J., Fukumoto, M., Takeda, Y., and Nishibuchi, M. 1997. Examination of diarrheagenicity of cytolethal distending toxin: suckling mouse response to the products of the cdtABC genes of Shigella dysenteriae. Infect. Immun. 65: 428-433.
15. Palmer, S.R., Gully, P.R., White, J.M., Pearson, A.D., Suckling, W.G., Jones, D.M., Rawes, J.C.L., and Penner, J.L. 1983. Water-borne outbreak of Campylobacter gastroenteritis. Lancet i: 287-290.
16. Parkhill, J., Wren, B.W., Mungall, K., Ketley, J.M., Churcher, C., Basham, D., Chillingworth, T., Davies, R.M., Feltwell, T., Holroyd, S., Jagels, K., Karlyshev, A.V., Moule, S., Pallen, M.J., Penn, C.W., Quail, M.A., Rajandream, M.A., Rutherford, K.M., van Vliet, A.H.M., Whitehead, S., and Barrell, B.G. 2000. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403: 665-668.
17. Pickett, C.L., Cottle, D.L., Pesci, E.C., and Bikah, G. 1994. Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes. Infect. Immun. 62: 1046-1051.
18. Pickett, C.L., Pesci, E.C., Cottle, D.L., Russell, G., Erdem, A.N., and Zeytin, H. 1996. Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB gene. Infect. Immun. 64: 2070-2078.
19. Pickett, C.L., and Whitehouse, C.A. 1999. The cytolethal distending toxin family. Trends. Microbiol. 7: 292-297.
20. Purdy, D., Buswell, C.M., Hodgson, A.E., McAlpine, K., Henderson, I., and Leach, S.A. 2000. Characterisation of cytolethal distending toxin (CDT) mutants of Campylobacter jejuni. J. Med. Microbiol. 49: 473-479.
21. Ryu, S., and Garges, S. 1994. Promoter switch in the Escherichia coli pts operon. J. Biol. Chem. 269: 4767-4772.
22. Schauder, S., and Bassler, B.L. 2001. The languages of bacteria. Genes Dev. 15: 1468-1480.
23. 2 arrest of the cell cycle in human T cells. J. Immunol. 165: 2612-2618.
24. 2-phase cell cycle block. Infect. Immun. 66: 1934-1940.
25. Wösten, M.M., Boeve, M., Koot, M.G., van Nuene, A.C., and van der Zeijst, B.A. 1998. Identification of Campylobacter jejuni promoter sequences. J. Bacteriol. 180: 594-599.