Neutralizing effects of an anti-vascular endothelial growth factor antibody on tooth movement

Angle Orthodontist

Volumn 75, Issue 5, 2005, Pages 797-804

  Kohno, Shinya ^a,b   Kaku, Masato ^b   Kawata, Toshitsugu ^b   Fujita, Tadashi ^b   Tsutsui, Keisuke ^a   Ohtani, Junji ^b   Tenjo, Kaoru ^b   Tohma, Yuiko ^b   Motokawa, Masahide ^b   Shigekawa, Mao ^b   Kamada, Hiroko ^b   Tanne, Kazuo ^b  

^a HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Anti VEGF polyclonal antibody; Bone remodeling; Experimental tooth movement; Osteoclast; VEGF

Indexed keywords

EID: 24744466569     PISSN: 00033219     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Igarashi K, Mitani H, Adachi H, Shinoda H. Anchorage and retentive effects of a bisphosphonate (AHBuBP) on tooth movements in rats. Am J Orthod Dentofacial Orthop. 1994;106:279-289.
2. Adachi H, Igarashi K, Mitani H, Shinoda H. Effects of topical administration of a bisphosphonate (risedronate) on orthodontic tooth movements in rats. J Dent Res. 1994;73:1478-1486.
3. Lee K, Sugiyama H, Imoto S, Tanne K. Effects of bisphosphonate on the remodeling of rat sagittal suture after rapid expansion. Angle Orthod. 2001;71:265-273.
4. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989;246:1306-1309.
5. Niida S, Kaku M, Amano H, Yoshida H, Kataoka H, Nishikawa S. Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med. 1999;190:293-298.
6. Kaku M, Niida S, Kawata T, Maeda N, Tanne K. Dose- and time-dependent changes in osteoclast induction after a single injection of vascular endothelial growth factor in osteopetrotic mice. Biomed Res. 2000;21:67-72.
7. Marks SC Jr, Lane PW. Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse. J Hered. 1976;67:1-18.
8. Marks SC Jr. Morphological evidence of reduced bone resorption in osteopetrotic (op) mice. Am J Anat. 1982;163:157-167.
9. Wiktor-Jedrzejczak W, Ahmed A, Szczylk C, Skelly RR. Hematological characterization of congenital osteopetrosis in op/op mouse. J Exp Med. 1982;156:1516-1527.
10. Felix R, Cecchini MG, Hofstetter W, Elford PR, Stutzer A, Freisch H. Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse. J Bone Miner Res. 1990;5:781-789.
11. Felix R, Cecchini MG, Freisch H. Macrophage colony-stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology. 1990;127:2592-2594.
12. Yoshida H, Hayashi S, Kunisada T, Ogawa H, Nishikawa S, Okamura H. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature. 1990;345:442-444.
13. Kaku M, Kohno S, Kawata T, Fujita T, Tokimasa C, Tsutsui K, Tanne K. Effects of vascular endothelial growth factor on osteoclast induction during tooth movement in mice. J Dent Res. 2001;80:1880-1883.
14. Kohno S, Kaku M, Tsutsui K, et al. Expression of vascular endothelial growth factor and the effects on bone remodeling during experimental tooth movement. J Dent Res. 2003;82:177-182.
15. Yoshino H, Morita I, Murota SI, Ishikawa I. Mechanical stress induces production of angiogenic regulators in cultured human gingival and periodontal ligament fibroblasts. J Periodontal Res. 2003;38:405-410.
16. Hammarström LE, Hanker JS, Toverud SU. Cellular differences in acid phosphatase isoenzymes in bone and teeth. Clin Orthop. 1971;78:151-167.
17. Olson TA, Mohanraj D, Ramakrishnan S. In Vivo neutralization of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) inhibits ovarian carcinoma-associated ascites formation and tumor growth. Int J Oncol. 1996;8:505-511.
18. Kim KJ, Li B, Houck K, Winer J, Ferrara N. The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors. 1992;7:53-64.
19. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature. 1993;362:841-844.
20. Kondo S, Asano M, Suzuki H. Significance of vascular endothelial growth factor/vascular permeability factor for solid tumor growth, and its inhibition by the antibody. Biochem Biophys Res Commun. 1993;194:1234-1241.
21. Takahashi Y, Mai M. Significance of angiogenesis and clinical application of anti-angiogenesis. Nippon Geka Gakkai Zasshi. 2001;102:381-384.