An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets

Basic and Clinical Pharmacology and Toxicology

Volumn 97, Issue 3, 2005, Pages 162-167

  Jin, Yong Ri ^a   Cho, Mi Ra ^a   Lee, Kyung Sup ^a   Lee, Jung Jin ^a   Lim, Yong ^a   Han, Xiang Hua ^a   Oh, Ki Wan ^a   Hong, Jin Tae ^a   Yoo, Hwan Soo ^a   Yun, Yeo Pyo ^a  

^a Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE; 12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 CHLORO 3 (4 ACETOPHENYL)AMINO 1,4 NAPHTHOQUINONE; ANTICOAGULANT AGENT; ARACHIDONIC ACID; CALCIUM ION; COLLAGEN; NQ 301; PROSTAGLANDIN H2; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR STIMULATING AGENT; THROMBOXANE B2; THROMBOXANE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTITHROMBOTIC ACTIVITY; ARTICLE; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG ACTIVITY; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; NONHUMAN; PRIORITY JOURNAL; RABBIT; THROMBOCYTE; THROMBOCYTE AGGREGATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; ARACHIDONIC ACID; BLOOD PLATELETS; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRINOLYTIC AGENTS; INHIBITORY CONCENTRATION 50; NAPHTHOQUINONES; PLATELET AGGREGATION INHIBITORS; PROSTAGLANDIN D2; RABBITS; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

ORYCTOLAGUS CUNICULUS;

EID: 24744464104     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto_973123.x     Document Type: Article

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