In vivo distribution of bismuth in the mouse brain: Influence of long-term survival and intracranial placement on the uptake and transport of bismuth in neuronal tissue

Basic and Clinical Pharmacology and Toxicology

Volumn 97, Issue 3, 2005, Pages 188-196

  Larsen, Agnete ^a   Stoltenberg, Meredin ^a   Søndergaard, Chris ^a   Bruhn, Mikkel ^a   Danscher, Gorm ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BISMUTH; HEAVY METAL; LEAD; LUBRICATING AGENT; MERCURY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOMETALLOGRAPHY; BLOOD BRAIN BARRIER; BRAIN TISSUE; BRAIN TOXICITY; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG DISTRIBUTION; GASTROINTESTINAL DISEASE; HYPOGLOSSAL NUCLEUS; HYPOTHALAMUS; IN VIVO STUDY; METAL BINDING; MOUSE; NERVE FIBER TRANSPORT; NERVOUS TISSUE; NEUROTOXICITY; NONHUMAN; OCULOMOTOR NUCLEUS; PRIORITY JOURNAL; PURKINJE CELL; RETICULUM CELL; SURVIVAL TIME;

ANIMALS; AXONAL TRANSPORT; AXONS; BISMUTH; BRAIN; BRAIN CHEMISTRY; ENVIRONMENTAL POLLUTANTS; INJECTIONS, INTRAPERITONEAL; LYSOSOMES; MICE; MICE, INBRED C57BL; MOTOR NEURONS; TISSUE DISTRIBUTION;

HELICOBACTER PYLORI;

EID: 24744456908     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto_973132.x     Document Type: Article

References (25)

1. Cowan, K., D. Conklin & M. Aschner: Metallothionein induction by bismuth in neonatal rat primary astrocyte cultures. Brain Res. 1996, 732, 106-112.
2. Danscher, G.: The autometallographic zinc-sulphide method. A new approach involving in vivo creation of nanometer-sized zinc sulphide crystal lattices in zinc-enriched synaptic and secretory vesicles. Histochem. J. 1996, 28, 361-373.
3. Danscher, G., M. Stoltenberg, K. Kemp & R. Pamphlett: Bismuth autometallography: Protocol, specificity and differentiation. J. Histochem. Cytochem. 2000, 48, 1503-1510.
4. Imam, S. K.: Advancements in cancer therapy with alpha-emitters: a review. Int. J. Radiat. Oncol. Biol. Phys. 2001, 51, 271-278.
5. Larsen, A., M. Stoltenberg, M. J. West & G. Danscher: Influence of bismuth on the number of neurons in cerebellum and hippocampus of normal and hypoxia-exposed mouse brain: A stereological study. J. Appl. Toxicol. 2005, in press.
6. Martin-Bouyer, G., G. Foulon, H. Guerbois & C. Barin: Epidemiological study of encephopathies following bismuth administration per os. Characteristics of intoxicated subjects: comparison with a control group. Clin. Toxicol. 1981, 11, 1277-1283.
7. Møller-Madsen, B.: Localization of mercury in CNS of the rat. An autometallographic study. Pharmacology & Toxicology 1994, 75 Suppl 1, 1-41.
8. Pamphlett, R., G. Danscher, J. Rungby & M. Stoltenberg: Tissue uptake of bismuth from shotgun pellets. Environ. Res. Section A 2000a, 82, 258-262.
9. Pamphlett, R., M. Stoltenberg, J. Rungby & G. Danscher: Uptake of bismuth in motor neurons of mice after single oral doses of bismuth compounds. Neurotoxicol. Teratol. 2000b, 22, 559-563.
10. Paxinos, B. J. & G. T. Frankling: The mouse brain in Stereotaxic coordinates, second ed. Elsevier Science, USA, 1997.
11. Pounder, R. E.: New developments in Helicobacter pylori eradication therapy. Scand. J. Gastroenterol. 1997, 32 Suppl 223, 43-45.
12. Qvigstad, G. & H. L. Waldum: Vismut. Tidsskr. Nor. Lægeforen. 1995, 115, 1353-1357.
13. Rodilla, V., A. T. Miles, W. Jenner & G. M. Hawksworth: Exposure of cultured human proximal tubular cells to cadmium, mercury, zinc and bismuth: toxicity and metallothionein induction. Chem. Biol. Interact. 1998, 115, 71-832.
14. Ross, J. F., R. D. Broadwell, M. R. Poston & G. T. Lawhorn. Highest brain bismuth levels and neuropathology are adjacent to fenestrated blood vessels in mouse brain after intra-peritoneal dosing of bismuth subnitrate. Toxicol. Appl. Pharmacol. 1994, 124, 191-200.
15. Ross, J. E., R. C. Switzer, M. R. Poston & G. T. Lawhorn: Distribution of bismuth in the brain after introperitoneal dosing of bismuth subnitrate in mice: implications for routes of entry of xenobiotic metals into the brain. Brain Res. 1996, 725, 137-154.
16. Rungby, J.: An experimental study on silver in the nervous system and on aspects of its general cellular toxicity. Dan. Med. Bull. 1990, 37, 442-449.
17. Slikkerveer, A. & F. A. de Wolff: Pharmacokinetics and toxicity of bismuth compounds. Toxicol Management Rev. 1989, 4, 303-323.
18. Stoltenberg, M., J.-A. Hogenhuis, J.-J. Hauw & G. Danscher: Autometallographic tracing of bismuth in human brain autopsies. J. Neuropathol. Exp. Neurol. 2001a, 60, 705-710.
19. Stoltenberg, M., J. D. Schiønning & G. Danscher: Retrograde axonal transport of bismuth: an autometallographic study. Acta Neuropathol 2001b, 101, 123-128.
20. Stoltenberg, M., A. Larsen, M. Zhao, G. Danscher & U. T. Brunk: Bismuth-induced lysosomal rupture in J774 cells. APMIS 2002, 110, 396-402.
21. Stoltenberg, M., J. D. Schiønning, M. J. West & G. Danscher: Bismuth-induced neuronal cell death in rat dorsal root ganglion. A stereological study. Acta neuropathol. 2003a, 105, 351-357.
22. Stoltenberg, M., L. Locht, A. Larsen, D. Jensen & G. Danscher: In vivo cellular uptake of bismuth ions from shotgun pellets. Histol. Histopathol. 2003b, 18, 781-785.
23. Sun, H., H. Li, I. Harvey & P. J. Sadler: Interactions of bismuth complexes with metallothionein (II). J. Biol. Chem. 1999, 274, 29094-29101.
24. Sun, H., H. Li, A. B. Mason, R. C. Woodworth & P. J. Sadler: Competitive binding of bismuth to transferring and albumin in aqueous solution and in blood plasma. J. Biol. Chem. 2001, 276, 8829-8835.
25. Tiekink, E. R.: Antimony and bismuth compounds in oncology. Crit. Rev. Oncol. Hematol. 2002, 42, 217-224.