Fully informed consent is impossible in surgical clinical trials

Canadian Journal of Surgery

Volumn 48, Issue 4, 2005, Pages 271-272

  Bernstein, Mark ^a  

^a TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BRACHYTHERAPY; CLINICAL PRACTICE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; ESOPHAGUS CANCER; FAMILY; GENE TRANSFER; GLIOBLASTOMA; HUMAN; INFORMED CONSENT; INTERPERSONAL COMMUNICATION; MEDICAL ERROR; METHODOLOGY; MIDDLE CEREBRAL ARTERY OCCLUSION; OUTCOMES RESEARCH; PATIENT CARE; PHYSICIAN; PRACTICE GUIDELINE; PROGNOSIS; PSYCHOLOGICAL ASPECT; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; SHORT SURVEY; STROKE; SURGICAL PATIENT; SURGICAL RISK; SURVIVAL RATE;

CLINICAL TRIALS; COMPREHENSION; HUMANS; INFORMED CONSENT; PATIENT ACCEPTANCE OF HEALTH CARE; SURGICAL PROCEDURES, OPERATIVE; TRUST; TRUTH DISCLOSURE;

EID: 24744452847     PISSN: 0008428X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (9)

1. Gardner MJ, Brophy RH, Demetrakopoulos D, Koob J, Hong R, Rana A, et al. Interventions to improve osteoporosis treatment following hip fracture. A prospective randomized trial. J Bone Joint Surg Am 2005;87:3-7.
2. Laperriere NJ, Leung PM, McKenzie S, Milosevic M, Wong S, Glen J, et al. Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. Int J Radiat Oncol Biol Phys 1998;41:1005-11.
3. Etchells E. Informed consent in surgical trials. World J Surg 1999;23:1215-9.
4. Bernstein M, Lumley M, Davidson G, Laperriere N, Leung P. Intracranial arterial occlusion due to high-activity iodine-125 brachytherapy for glioblastoma. J Neurooncol 1993;17:253-60.
5. Kimmelman J, Palmour N. Therapeutic optimism in the consent form of phase I gene transfer trials: an empirical analysis. J Med Ethics 2005;31:209-14.
6. Henderson GE, Davis AM, King NM, Easter MM, Zimmer CR, Rothschild BB, et al. Uncertain benefit: investigators' views and communications in early phase gene transfer trials. Mol Ther 2004;10:225-31.
7. McKneally MF, Martin DK. An entrustment model of consent for surgical treatment of life-threatening illness: perspective of patients requiring esophagectomy. J Thorac Cardiovasc Surg 2000;120:264-9.
8. Bernstein M, Potvin D, Martin DK. A qualitative study of attitudes toward error in patients facing brain tumour surgery. Can J Neurol Sci 2004;31:208-12.
9. Bernstein M. Conflict of interest: It is ethical for an investigator to also be the care-giver in a clinical trial. J Neurooncol 2003; 63:107-8.