Glycoprotein Ia 807TT/873AA genotype is not associated with myocardial infarction

Anadolu Kardiyoloji Dergisi

Volumn 5, Issue 3, 2005, Pages 182-186

  Kömürcü, Evrim ^a   Işsever, Halim ^a   Erginel Ünaltuna, Nihan ^a,b  

^a ISTANBUL UNIVERSITY   (Turkey)

^b NONE   (Turkey)

Author keywords

Dimorphism; Gycoprotein la; Myocardial infarction

Indexed keywords

ALPHA2 INTEGRIN; COLLAGEN RECEPTOR; DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; THROMBOCYTE RECEPTOR;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENOTYPE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TURKEY (REPUBLIC);

ADULT; CASE-CONTROL STUDIES; DNA PRIMERS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HUMANS; INTEGRIN ALPHA2BETA1; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; TURKEY;

EID: 24744431909     PISSN: 13028723     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. Hereditary variation in platelet integrin α2β1 density is associated with two silent polymorphisms in the α2 gene coding sequence. Blood 1997; 89: 1939-43.
2. Kritzik M, Savage B, Nugent DJ, et al. Nucleotide polymorphisms in the α2 gene define multiple alleles that are associated with differences in platelet α2β1 density. Blood 1998; 92: 2382-8.
3. Moshfegh K, Wuillemin WA, Redondo M, et al. Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: a case-control study. Lancet 1999; 353: 351-4.
4. Dinauer DM, Friedman KD, Hessner MJ. Allelic distribution of the glycoprotein Ia (α2-integrin) C807T/G873A dimorphisms among Caucasian venous thrombosis patients and six racial groups. Br J Haematol. 1999; 107: 563-5.
5. Croft SA, Hampton KK, Sorrell JA, et al. The GPIa C807T dimorphism associated with platelet collagen receptor density is not a risk for myocardial infarction. Br J Haematol. 1999; 106: 771-6.
6. Santoso S, Kunicki TJ, Kroll H, Haberbosch W, Gardemann A. Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood 1999; 93: 2449-53.
7. Carlsson LE, Santoso S, Spitzer C, Kessler C, Greinacher A. The α2 gene coding sequence T807/A873 of the platelet collagen receptor integrin α2β1 might be a genetic risk factor for the development of stroke in younger patients. Blood 1999; 93: 3583-6.
8. Kawasaki ES. Sample preparation from blood, cells and other fluids. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, editors. PCR Protocols: A Guide to Methods and Applications. San Diego, CA, USA: Academic; 1990. p146.
9. Komurcu E, Erginel-Unaltuna N. Platelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey. Am J Hematol. 2002; 69: 83-4.
10. Casorelli I, De Stefano V, Leone AM, et al. The C807T/G873A polymorphism in the platelet glycoprotein Ia gene and the risk of acute coronary syndrome in the Italian population. Br J Haematol 2001; 114: 150-4.
11. Leone AM, De Stefano V, Burzotta F, et al. Glycoprotein Ia C807T gene polymorphism and increased risk of recurrent acute coronary syndromes: a five year follow up. Heart 2004; 90: 567-9.
12. Roest M, Banga JD, Grobbee DE, et al. Homozygosity for 807 T polymorphism in α2 subunit of platelet α2β1 is associated with increased risk of cardiovascular mortality in high-risk women. Circulation 2000; 102: 1645-50.
13. Park S, Park HY, Park C, et al. Association of the gene polymorphisms of platelet glycoprotein Ia and IIb/IIIa with myocardial infarction and extent of coronary artery disease in the Korean population.Yonsei Med J 2004; 45: 428-34.
14. Anvari A, Janisiw M, Turel Z, et al. Platelet glycoprotein Ia gene dimorphism α2-807 in malignant arrhythmia in coronary artery disease. Thromb Res 2000; 98: 281-6.
15. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 1977; 62: 707-14.
16. Hokanson JE, Austin MA. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies. J Cardiovasc Risk 1996; 3: 213-9.
17. Bersot TP, Palaoglu KE, Mahley RW. Managing dyslipidemia in Turkey: suggested guidelines for a population characterized by low levels of high density lipoprotein cholesterol. Anadolu Kardiyol Derg 2002; 2: 315-22.
18. Onat A. Risk factors and cardiovascular disease in Turkey. Atherosclerosis 2001; 156: 1-10.
19. Onat A. Lipids, lipoproteins and apolipoproteins among Turks, and impact on coronary heart disease. Anadolu Kardiyol Derg 2004; 4: 236-45.