Lack of survival advantage in patients with advanced, resectable squamous cell carcinoma of the oral cavity receiving induction chemotherapy with cisplatin (CDDP), docetaxel (TXT) and 5-fluorouracil (5FU)

Kobe Journal of Medical Sciences

Volumn 50, Issue 6, 2004, Pages 189-196

  Umeda, Masahiro ^a   Komatsubara, Hideki ^a   Ojima, Yasutaka ^a   Minamikawa, Tsutomu ^a   Shigeta, Takashi ^a   Shibuya, Yasuyuki ^a   Yokoo, Satoshi ^a   Komori, Takahide ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cisplatin; Docetaxel; Induction chemotherapy; Oral cancer

Indexed keywords

CISPLATIN; DOCETAXEL; FLUOROURACIL; GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ADVANCED CANCER; AGED; ALOPECIA; ARTICLE; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER SURGERY; CANCER SURVIVAL; CHEMOTHERAPY INDUCED EMESIS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIZZINESS; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; LEUKOPENIA; MALE; MOUTH CARCINOMA; NAUSEA; NEUTROPENIA; PROGNOSIS; SQUAMOUS CELL CARCINOMA; STOMATITIS; SURVIVAL RATE; SURVIVAL TIME; THROMBOCYTOPENIA;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; FEMALE; FLUOROURACIL; HUMANS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NEOADJUVANT THERAPY; PROGNOSIS; SURVIVAL RATE; TAXOIDS;

EID: 24644525003     PISSN: 00232513     EISSN: 18830498     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Al-Sarraf, M., LeBlanc, M., Giri, P.G., Fu, K.K., Cooper, J., Vuong, T., Furastiere, A.A., Adams, G., Sakr, W.A., Schuller, D.E., and Ensley, J.F. 1998. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized intergroup study. J Clin Oncol 16: 1310-1317.
2. Basu, S., Khanra, M., Dash, B., Majumdar, J,, Biswas, J., and Chaudhuri, P. 1999. The role of neoadjuvant and adjuvant chemotherapy regimens consisting of different combinations of drugs in the treatment of advanced oral cancer. Med Oncol 16: 199-203.
3. Clayman, G.L., Weber, K.S., Guillamondegui, O., Byers, R.M., Wolf, P.F., Frankenthaler, R.A., Morrison, W.H., Garden, A.S., Hong, W.K., and Goepfert, H. 1995. Laryngeal preservation for advanced laryngeal and hypopharyngeal cancers. Arch Otolaryngol Head Neck Surg 121: 219-223.
4. Earle, A.S., Adelstein, D.J., Vlastou, C., Sharan, V.M., and Indresano, A.T. 1990. Treatment of oral squamous cell carcinoma with simultaneous chemotherapy ans radiation: results and surgical implications. J Oral Maxillofac Surg 48: 367-372.
5. Giralt, J.L., Gonzalez, J., del Campo, J.M., Maldonado, J., Sanz, X., Pamias, J., Eraso, A., Bescos, S., and Raspall, G. 2000. Preoperative induction chemotherapy followed by concurrent chemoradiotherapy in advanced carcinoma of the oral cavity and oropharynx. Cancer 89: 939-945.
6. Grau, J.J., Estape, J., Blanch, J.L., Vilalta, A., Castro, V., Biete, A., and Daniels, M. 1996. Neoadjuvant and adjuvant chemotherapy in the multidisciplinary treatment of oral cancer stage III or IV. Eur J Cancer B Oral Oncol 32B: 238-241.
7. Hill, B.T., and Price, L.A. 1994. Lack of survival advantage in patients with advanced squamous cell carcinomas of the oral cavity receiving neoadjuvant chemotherapy prior to local therapy, despite achieving an initial high clinical complete remission rate. Am J Clin Oncol 17: 1-5.
8. Hong, W.K., Lippman, S.M., and Wolf, G.T. 1993. Recent advances in head and neck cancer -Laryngeal preservation and cancer chemoprevention; seventeenth annual Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res 53: 5113-5120.
9. International Nasopharynx Cancer Study Group. 1996. Preliminary results of randomized trial comparing neoadjuvant chemotherapy (cisplatin, epirubicin, bleomycin) plus radiotherapy vs. radiotherapy alone in nstage IV (>N2, M0) undifferentiated nasopharyngeal carcinoma: A positive effect on progression-free survival. Int J Radiat Oncol Phys 35: 463-469.
10. Kirita, T., Ohgi, K., Kawakami, M., Miyawaki, S., Okamoto, M., Yamanama, Y., and Sugimura, M. 2002. Primary tumour resection of tongue carcinoma based on response to preoperative therapy. Int J Oral Maxillofac Surg 31: 267-272.
11. Kohno, N., Ichimawa, G., Nakazawa, E., Kusunoki, M., and Nishiya, M. 1995. Induction chemotherapy with cisplatin, etoposide, and mitomycin-C (PEM) regimen in advanced cases with cancer of pharynx and oral cavity. Auris Nasus Larynx 22: 49-52.
12. Mazeron, J.J., Martin, M., Brun, B., Grimard, L., Lelievre, G., Vergnes, L., Haddad, E., Feuilhade, F., Piedbois, P., and Strunski, W. 1992. Induction chemotherapy in head and neck cancer: results of a phase III trial. Head Neck 14: 85-91.
13. Nishioka, T., Shirato, H., Kitahara, T., Nishiyama, N., Inuyama, Y., and Fukuda, S. 1996. Treatment results of nasopharyngeal carcinoma: Effect of neoadjuvant chemotherapy. Head and Neck Cancer 22: 135-138.
14. Okura, M., Hiranuma, T., Adachi, T., Ogura, T., Aikawa, T., Yoshioka, H., Hayashido, Y., Kogo, M., and Matsuya, T. 1998. Induction chemotherapy is associated with an increase in the incidence of locoregional recurrence in patients with carcinoma of the oral cavity: results from a single institution. Cancer 82: 804-815.
15. Schuller, D.E., Metch, B., Stein, D.W., Mattox, D., and McCracken, J.D. 1988. Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group. Laryngoscope 98: 1205-1211.
16. Shimasato, Y., Oboshi, S., and Baba, K. 1971. Histological evaluation of effects of radiotherapy and chemotherapy for carcinomas. Jpn J Clin Oncol 1: 19-35.
17. The Department of Veterans Affairs Laryngeal Study Group. 1991. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 324: 1685-1690.