Humoral immune response to rotavirus NSP4 enterotoxin in Spanish children

Journal of Medical Virology

Volumn 77, Issue 2, 2005, Pages 317-322

  Rodríguez Díaz, Jesús ^a   Montava, Rebeca ^a   García Díaz, Ana ^a   Buesa, Javier ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

Antibodies; Enterotoxin; Non structural protein 4; Rotavirus gastroenteritis

Indexed keywords

ENTEROTOXIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PROTEIN NSP4; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ADULT; ANIMAL CELL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN RECOGNITION; ARTICLE; BACULOVIRUS; CLINICAL ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DIARRHEA; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROENTERITIS; GENOTYPE; HUMAN; HUMORAL IMMUNITY; NONHUMAN; PRESCHOOL CHILD; PROTEIN EXPRESSION; ROTAVIRUS; SERUM; SPAIN; VIRUS RECOMBINANT; VIRUS STRAIN;

ADULT; ANTIBODIES, VIRAL; CHILD, PRESCHOOL; ENTEROTOXINS; GLYCOPROTEINS; HUMANS; INFANT; ROTAVIRUS; ROTAVIRUS INFECTIONS; SPAIN; TOXINS, BIOLOGICAL; VIRAL NONSTRUCTURAL PROTEINS;

ROTAVIRUS;

EID: 24644451072     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20450     Document Type: Article

References (44)

1. Ball JM, Tian P, Zeng CQ, Morris AP, Estes MK. 1996. Age-dependent diarrhoea induced by a rotaviral nonstructural glycoprotein. Science 272:101-104.
2. Barnes GL, Lund JS, Mitchell SV, De Bruyn L, Piggford L, Smith AL, Furmedge J, Masendycz PJ, Bugg HC, Bogdanovic-Sakran N, Carlin JB, Bishop RF. 2002. Early phase II trial of human rotavirus vaccine candidate RV3. Vaccine 20:2950-2956.
3. Berkova Z, Morris AP, Estes MK. 2003. Cytoplasmic calcium measurement in rotavirus enterotoxin-enhanced green fluorescent protein (NSP4-EGFP) expressing cells loaded with Fura-2. Cell Calcium 34: 55-68.
4. Bern C, Glass RI. 1994. Viral infections of gastrointestinal tract. In: Kapikian A, editor. Impact of diarrhoeal deseases worldwide. New York: Marcel Dekker, Inc. pp 1-26.
5. Bishop RF. 1996. Natural history of human rotavirus infections. Arch Virol Suppl 12:119-128.
6. Borgan MA, Mori Y, Ito N, Sugiyama M, Minamoto N. 2003. Antigenic analysis of nonstructural protein (NSP) 4 of group A avian rotavirus strain PO-13. Microbiol Immunol 47:661-668.
7. Browne EP, Bellamy AR, Taylor JA. 2000. Membrane-destabilizing activity of rotavirus NSP4 is mediated by a membrane-proximal amphipathic domain. J Gen Virol 81:1955-1959.
8. Cao XR, Akihara S, Fang ZY, Nakagomi O, Ushijima H. 1999. Genetic variation in the VP4 and NSP4 genes of human rotavirus serotype 3 (G3 type) isolated in China and Japan. Microbiol Immunol 43: 171-175.
9. Ciarlet M, Liprandi F, Conner ME, Estes MK. 2000. Species specificity and interspecies relatedness of NSP4 genetic groups by comparative NSP4 sequence analyses of animal rotaviruses. Arch Virol 145: 371-383.
10. Colomina J, Gil MT, Codoñer P, Buesa J. 1998. Viral proteins VP2, VP6 and NSP2 are strongly precipitated by serum and fecal antibodies from children with rotavirus infection. J Med Virol 56:58-65.
11. Conner ME, Crawford SE, Barone C, Estes MK. 1993. Rotavirus vaccine administered parenterally induces protective immunity. J Virol 67:6633-6641.
12. Contreras JF, Menchaca GE, Padilla-Noriega L, Tamez RS, Greenberg HB, Lopez S, Arias CF. 1995. Heterogeneity of VP4 neutralization epitopes among serotype P1A human rotavirus strains. Clin Diagn Lab Immunol 2:506-508.
13. Coulson BS. 1993. Typing of human rotavirus VP4 by an enzyme immunoassay using monoclonal antibodies. J Clin Microbiol 31: 1-8.
14. Crawford SE, Estes MK, Ciarlet M, Barone C, O'Neal CM, Cohen J, Conner ME. 1999. Heterotypic protection and induction of a broad heterotypic neutralization response by rotavirus-like particles. J Virol 73:4813-4822.
15. Cunliffe NA, Woods PA, Leite JP, Das BK, Ramachandran M, Bhan MK, Hart CA, Glass RI, Gentsch JR. 1997. Sequence analysis of NSP4 gene of human rotavirus allows classification into two main genetic groups. J Med Virol 53:41-50.
16. Dong Y, Zeng CQ, Ball JM, Estes MK, Morris AP. 1997. The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate production. Proc Natl Acad Sci USA 94:3960-965.
17. Estes MK. 2001. Rotaviruses and their replication. In: Knipe DM, Howley PM, editors. Fields virology, 4th edition. Philadelphia: Lippincott, Williams and Wilkins. pp 1747-1785.
18. Estes MK. 2003. The rotavirus NSP4 enterotoxin: Current status and challenges. In: Gray J, Desselberger U, editors. Viral gastroenteritis. Amsterdam: Elsevier. pp 207-224.
19. Gorrell RJ, Bishop RF. 1997. Production of reassortant viruses containing human rotavirus VP4 and SA11 VP7 for measuring neutralizing antibody following natural infection. Clin Diagn Lab Immunol 4:509-514.
20. Halaihel N, Lievin V, Ball JM, Estes MK, Alvarado F, Vasseur M. 2000. Direct inhibitory effect of rotavirus NSP4(114-135) peptide on the Na(+)-D-glucose symporter of rabbit intestinal brush border membrane. J Virol 74:9464-9470.
21. Herrmann JE, Chen SC, Jones DH, Tinsley-Bown A, Fynan EF, Greenberg HB, Farrar GH. 1999. Immune responses and protection obtained by oral immunization with rotavirus VP4 and VP7 DNA vaccines encapsulated in microparticles. Virology 259:148-153.
22. Horie Y, Nakagomi O, Koshimura Y, Nakagomi T, Suzuki Y, Oka T, Sasaki S, Matsuda Y, Watanabe S. 1999. Diarrhoea induction by rotavirus NSP4 in the homologous mouse model system. Virology 262:398-407.
23. Huang H, Schroeder F, Zeng C, Estes MK, Schoer JK, Ball JM. 2001. Membrane interactions of a novel viral enterotoxin: Rotavirus nonstructural glycoprotein NSP4. Biochemistry 40:4169-4180.
24. Huang H, Schroeder F, Estes MK, McPherson T, Ball JM. 2004. The interaction(s) of rotavirus NSP4 C-terminal peptides with model membranes. Biochem J 380:723-733.
25. Iturriza-Gomara M, Anderton E, Kang G, Gallimore C, Phillips W, Desselberger U, Gray J. 2003. Evidence for genetic linkage between the gene segments encoding NSP4 and VP6 proteins in common and reassortant human rotavirus strains. J Clin Microbiol 41:3566-3573.
26. Jiang B, Gentsch JR, Glass RI. 2002. The role of serum antibodies in the protection against rotavirus disease: An overview. Clin Infect Dis 34:1351-1361.
27. Johansen K, Hinkula J, Espinoza F, Levi M, Zeng C, Ruden U, Vesikari T, Estes M, Svensson L. 1999. Humoral and cell-mediated immune responses in humans to the NSP4 enterotoxin of rotavirus. J Med Virol 59:369-377.
28. Kapikian AK, Hoshino Y, Chanock RM. 2001. Rotaviruses. In: Knipe DM, Howley PM, editors. Fields virology, 4th edition. Philadelphia: Lippincott, Williams and Wilkins. pp 1787-1883.
29. Kirkwood CD, Palombo EA. 1997. Genetic characterization of the rotavirus nonstructural protein, NSP4. Virology 236:258-265.
30. Mori Y, Borgan MA, Ito N, Sugiyama M, Minamoto N. 2002. Sequential analysis of nonstructural protein NSP4s derived from group A avian rotaviruses. Virus Res 89:145-151.
31. Morris AP, Scott JK, Ball JM, Zeng CQ, O'Neal WK, Estes MK. 1999. NSP4 elicits age-dependent diarrhoea and Ca(2+)mediated I(-) influx into intestinal crypts of CF mice. Am J Physiol 277:G431-G444.
32. Offit PA. 2002. The future of rotavirus vaccines. Semin Pediatr Infect Dis 13:190-195.
33. Parashar U, Bresee J, Glass R. 2003a. The global burden of diarrhoeal disease in children. Bull World Health Organ 81:236.
34. Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass RI. 2003b. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 9:565-572.
35. Ray P, Malik J, Singh RK, Bhatnagar S, Bahl R, Kumar R, Bhan MK. 2003. Rotavirus nonstructural protein NSP4 induces heterotypic antibody responses during natural infection in children. J Infect Dis 187:1786-1793.
36. Richardson SC, Grimwood K, Bishop RF. 1993. Analysis of homotypic and heterotypic serum immune responses to rotavirus proteins following primary rotavirus infection by using the radioimmunoprecipitation technique. J Clin Microbiol 31:377-385.
37. Rodríguez-Díaz J, López-Andújar P, García-Díaz A, Cuenca J, Montava R, Buesa J. 2003. Expression and purification of polyhistidine-tagged rotavirus NSP4 proteins in insect cells. Protein Expr Purif 31:207-212.
38. Rodríguez-Díaz J, Monedero V, Pérez-Martínez G, Buesa J. 2004. Single-chain variable fragment (scFv) antibodies against rotavirus NSP4 enterotoxin generated by phage display. J Virol Methods 121: 231-238.
39. Tian P, Hu Y, Schilling WP, Lindsay DA, Eiden J, Estes MK. 1994. The nonstructural glycoprotein of rotavirus affects intracellular calcium levels. J Virol 68:251-257.
40. Tian P, Estes MK, Hu Y, Ball JM, Zeng CQ, Schilling WP. 1995. The rotavirus nonstructural glycoprotein NSP4 mobilizes Ca2+ from the endoplasmic reticulum. J Virol 69:5763-5772.
41. Tian P, Ball JM, Zeng CQ, Estes MK. 1996. The rotavirus nonstructural glycoprotein NSP4 possesses membrane destabilization activity. J Virol 70:6973-6981.
42. Yu J, Langridge WH. 2001. A plant-based multicomponent vaccine protects mice from enteric diseases. Nat Biotechnol 19:548-552.
43. Yuan L, Ishida SI, Honma S, Patton JT, Hodgins DC, Kapikian AZ. 2004. Homotypic and heterotypic serum isotype-specific antibody responses to rotavirus nonstructural protein 4 and viral protein (VP) 4, VP6 and VP7 in infants who received selected live oral rotavirus vaccines. J Infect Dis 189:1834-1845.
44. Zhang M, Zeng CQ-Y, Morris MP, Estes MK. 2000. A functional NSP4 enterotoxin peptide secreted from rotavirus-infected cells. J Virol 74:11663-11670.