Following directed evolution with crystallography: Structural changes observed in changing the substrate specificity of dienelactone hydrolase

Acta Crystallographica Section D: Biological Crystallography

Volumn 61, Issue 7, 2005, Pages 920-931

  Kim, Hye Kyung ^a   Liu, Jian Wei ^a   Carr, Paul D ^a   Ollis, David L ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHYL ACETATE; ALPHA-NAPHTHYL ACETATE; BENZYLSULFONYL FLUORIDE; CARBOXYLESTERASE; CARBOXYMETHYLENEBUTENOLIDASE; NAPHTHOL DERIVATIVE;

ARTICLE; BINDING SITE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; DRUG ANTAGONISM; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; METHODOLOGY; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CARBOXYLIC ESTER HYDROLASES; CRYSTALLOGRAPHY, X-RAY; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; NAPHTHOLS; PHENYLMETHYLSULFONYL FLUORIDE; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY;

EID: 24644450583     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444905009042     Document Type: Article

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