Lacrimal gland involvement in graft-versus-host disease: A murine model

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 8, 2005, Pages 2692-2697

  Hassan, Adam S ^a   Clouthier, Shawn G ^b   Ferrara, James L M ^b   Stepan, Alexandra ^a   Mian, Shahzad I ^a   Ahmad, Amjad Z ^a   Elner, Victor M ^a,b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LACRIMAL GLAND; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; ACUTE DISEASE; ALLOTRANSPLANTATION; ANIMAL; BONE MARROW; BONE MARROW TRANSPLANTATION; C57BL MOUSE; DISEASE MODEL; FEMALE; FIBROSIS; IMMUNOLOGY; IMMUNOPHENOTYPING; LACRIMAL APPARATUS; LACRIMAL GLAND DISEASE; MOUSE; PATHOLOGY;

ACUTE DISEASE; ANIMALS; BONE MARROW; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; GRAFT VS HOST DISEASE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LACRIMAL APPARATUS; LACRIMAL APPARATUS DISEASES; MICE; MICE, INBRED C57BL; TRANSPLANTATION, HOMOLOGOUS;

EID: 24644433967     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-0040     Document Type: Article

References (31)

1. Jack MK, Jack G, Sale GE, Shulman. HM, Sullivan KM. Ocular manifestations of graft-v-host disease. Arch Ophthalmol. 1983;101:1080-1084.
2. Kerty E, Vigander K, Flage T, et al. Ocular findings in allogeneic stem cell transplantation without total body irradiation. Ophthalmology. 1999;106:1334-1338.
3. Jabs DA, Wingard J, Green WR, et al. The eye in bone marrow transplantation. III. Conjunctival graft-vs-host disease. Arch Ophthalmol. 1989;107:1343-1348.
4. Saito T, Shinagawa K, Takenaka K, et al. Ocular manifestation of acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. Int J Hematol. 2002;75:332-334.
5. Janin A, Facon T, Gastier P, et al. Pseudomembranous conjunctivitis following bone marrow transplantation: immunopathological and ultrastructural study of one case. Hum Pathol. 1996;27:307-309.
6. Kim RY, Anderlini P, Nader AA, et al. Scleritis as the initial clinical manifestation of graft-versus-host disease after allogeneic bone marrow transplantation. Am J Ophthalmol. 2002;133:843-845.
7. Mencucci R, Rossi Ferrini C, Bosi A, et al. Ophthalmological aspects in allogeneic bone marrow transplantation: Sjogren-like syndrome in graft-versus-host disease. Eur J Ophthalmol. 1997;7:13-18.
8. Ogawa Y, Okamoto S, Wakui M, et al. Dry eye after haematopoietic stem cell transplantation. Br J Ophthalmol. 1999;83:1125-1130.
9. Franklin RM, Kenyon KR, Tutschka PJ, et al. Ocular manifestation of graft-vs-host disease. Ophthalmology. 1983;90:4-13.
10. Tichelli A, Duell T, Weiss M, et al. Late-onset keratoconjuctivitis sicca syndrome after bone marrow transplantation: incidence and risk factors. European Group or Blood and Marrow Transplantation (EBMT) Working Party on Late Effects. Bone Marrow Transplant. 1996;17:1105-1111.
11. Jabs DA, Hirst LW, Green WR, et al. The eye in bone marrow transplantation. II. Histopathology. Arch of Ophthalmol. 1983;101:585-590.
12. Gratwhol AA, Moutsopoulos HM, Chused TM, et al. Sjogren-type syndrome after allogeneic bone marrow transplantation. Ann of Int Med. 1977;87:703-706.
13. Ogawa Y, Kuwana M, Yamazaki K, et al. Periductal area as the primary site for T-cell activation in lacrimal gland chronic graft-versus-host disease. Invest Ophthalmol Vis Sci. 2003;44:1888-1896.
14. Hill GR, Crawford JM, Cooke KJ, et al. Total body irradiation effects on acute graft versus host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood. 1997;90:3204-3213.
15. Cooke KR, Gerbitz A, Crawford JM, et al. LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation. J Clin Invest. 2001;107:1581-1589.
16. Cooke KR, Kobzik L, Martin TR, et al. An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation, I: the roles of minor H antigens and endotoxin. Blood. 1996;8:3230-3239.
17. Blatter DD, Crawford JM, Ferrara JLM. Nuclear magnetic resonance of hepatic graft-versus-host disease in mice. Transplantation (Baltimore). 1990;50:1011-1018.
18. Snover DC, Weisdorf SA, Vercellotti GM, Rank B, Hutton S, McGlave P. A histopathologic study of gastric and small intestinal graft-versus-host disease following allogeneic bone marrow transplantation. Hum Pathol. 1985;15:387-392.
19. Snover DC, Weisdorf SA, Ramsay NK, McGlave P, Kersey JH. Hepatic graft-versus-host disease: a study of the predictive value of liver biopsy in diagnosis. Hepatology. 1984;4:123-130.
20. Antin JH, Ferrara JL. Cytokine dysregulation and acute graft-versus-host disease. Blood. 1992;80:2964-2968.
21. Abhyankar S, Gilliland DG, Ferrara JL. Interleukin-1 is a critical effector molecule during cytokine dysregulation in graft versus host disease to minor histocompatibility antigens. Transplantation. 1993;56:1518-1523.
22. Xun C, Brown SA, Jennings CD, et al. Acute graft-versus-host-like disease induced by transplantation of human activated natural killer cells into SCID mice. Transplantation. 1993;56:409-417.
23. O'Garra A, Murphy K. Role of cytokines in determining T-lymphocyte function. Curr Opin Immun. 1994;6:458-466.
24. Swain SL, Bradley LM, Croft M, et al. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev. 1991;123:115-144.
25. Bekkum DW, Roodenburg J, Heidt PJ, van der Waaij D. Mitigation of secondary disease of allogeneic mouse radiation chimeras by modification of the intestinal micro flora. J Nat Canc Inst. 1974; 52:40140-40144.
26. Matuschak GM, Mattingly ME, Tredway TL, Lechner AJ. Liver-lung interactions during E. coli endotoxemia: TNF-alpha:leukotriene axis. Am J Resp Crit Care Med. 1994;149:41-49.
27. Ichiba T, Teshima T, Kuick R, et al. Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays. Blood. 2003;102:763-771.
28. Slayback DL, Dobkins JA, Harper JM, Allen RD. Genetic factors influencing the development of chronic graft-versus-host disease in a murine model. Bone Marrow Transplant. 2000;26:931-938.
29. Peszkowski MJ, Fujiwara K, Warfvinge G, Larsson A. Experimental graft versus host disease in the (B NxLEW) F1 rat hybrid as a model for autoimmune disease: study of early adenitis in lacrimal and salivary glands. Autoimmunity. 1996;24:101-111.
30. Ogawa Y, Yamazaki K, Kuwana M, et al. A significant role of stromal fibroblasts in rapidly progressive dry eye in patients with chronic GVHD. Invest Ophthalmol Vis Sci. 2001;42:111-119.
31. Ogawa Y, Kuwana M. Dry eye as a major complication associated with chronic graft-versus-host disease after hematopoietic stem cell transplantation. Cornea. 2003;22:S19-S27.